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What are the side effects of citric acid additive?

4 min read

According to industry data, approximately 99% of the citric acid used in foods and beverages is manufactured via fermentation using the mold Aspergillus niger, not from natural citrus fruit. The side effects of citric acid additive can range from minor stomach upset to more serious inflammatory reactions in sensitive individuals.

Quick Summary

Citric acid additive may cause stomach upset, dental enamel erosion, and skin irritation. Allergic or inflammatory responses are also possible, particularly with the manufactured version derived from mold fermentation.

Key Points

  • Manufactured vs. Natural: Most citric acid in products is made from a mold (Aspergillus niger), not from citrus fruits.

  • Dental Risks: The high acidity in citric acid can erode tooth enamel over time, leading to sensitivity and decay.

  • Gastrointestinal Distress: High consumption can cause stomach upset, nausea, vomiting, or abdominal pain in some people.

  • Inflammatory Reactions: Manufactured citric acid may trigger inflammatory responses in sensitive individuals, with symptoms like joint pain and fatigue.

  • Allergic Potential: Rare allergic reactions, including hives and breathing issues, have been reported, possibly due to mold residues.

  • Minimize Intake: Reading labels, reducing processed food consumption, and practicing good oral hygiene can mitigate risks.

In This Article

Understanding Citric Acid

Citric acid is a common food additive found in a wide range of products, from sodas and candies to canned vegetables and frozen foods. It is used as a preservative, a flavoring agent to add a sour taste, and a stabilizer. While naturally present in citrus fruits, most citric acid used commercially is manufactured through a fermentation process involving the fungus Aspergillus niger, also known as black mold. Although the Food and Drug Administration (FDA) generally recognizes it as safe (GRAS), its widespread and high consumption has raised concerns about potential side effects, particularly with the manufactured form.

Manufactured vs. Natural Citric Acid

The key distinction lies in how the citric acid is produced. Natural citric acid is derived directly from fruits like lemons and limes, while manufactured citric acid (MCA) is created in a lab setting through fermentation. Both have the same chemical formula, but some anecdotal evidence and case reports suggest that the manufacturing process for MCA may leave behind mold residues or other impurities. These by-products are believed by some researchers to be the root cause of adverse inflammatory reactions in certain people. Conversely, no such issues are reported with consuming natural citric acid from fruits.

Common Adverse Reactions

Gastrointestinal Distress

Consuming large amounts of citric acid, especially from highly processed foods or certain medications, can lead to stomach-related issues. These can include:

  • Nausea and vomiting
  • Upset stomach or general gastrointestinal issues
  • Abdominal cramping or pain
  • In more severe cases, excessive intake might lead to diarrhea

Dental Erosion

Due to its high acidity, frequent exposure to citric acid is a primary cause of dental enamel erosion. This can lead to increased tooth sensitivity, yellowing of the teeth, and a higher risk of developing cavities. The risk is particularly high with sugary, acidic drinks like soda, where the combination of acid and sugar creates a 'double trouble' for tooth enamel. Enamel does not regrow, so prevention is key.

Skin and Eye Irritation

Concentrated forms of citric acid, often found in cleaning agents, can cause irritation upon contact with the skin or eyes. This can manifest as stinging, redness, and itching. When using products with high concentrations, protective measures like gloves are recommended. In cosmetic products, where concentrations are low, irritation is much less common.

Inflammatory and Allergic Reactions

For a small subset of individuals, ingesting manufactured citric acid may trigger significant inflammatory reactions. Case reports have detailed symptoms such as:

  • Joint pain with swelling and stiffness
  • Muscular pain
  • Difficulty breathing
  • Fatigue
  • Irritable bowel symptoms Allergic reactions, though considered rare, can also occur and may present with hives, swelling, and difficulty breathing.

Respiratory Issues

Inhalation of citric acid in its powdered form, especially in occupational settings, can irritate the respiratory tract. For those with pre-existing respiratory conditions like asthma, this can trigger coughing, sneezing, and shortness of breath.

Tips for Reducing Your Citric Acid Intake

If you are sensitive to citric acid or simply wish to reduce your intake, consider the following steps:

  • Read labels carefully: Pay attention to ingredient lists on processed foods, beverages, and even supplements. Look for the term "citric acid" or "E330".
  • Choose natural options: Opt for whole, natural foods instead of processed alternatives that rely on additives for preservation or flavor.
  • Limit acidic drinks: Reduce consumption of sodas, sports drinks, and certain juices that are high in citric acid. When you do, consider using a straw to minimize contact with your teeth.
  • Practice good dental hygiene: Wait at least 30 minutes after consuming acidic foods or drinks before brushing your teeth to avoid damaging softened enamel. Rinsing with water is helpful.
  • Consult a professional: If you suspect an intolerance or allergy to manufactured citric acid, consult a healthcare provider for proper diagnosis and guidance.
Feature Manufactured Citric Acid Natural Citric Acid
Source Produced via fermentation using the mold Aspergillus niger Derived directly from citrus fruits like lemons and limes
Purity May contain mold residues or impurities from manufacturing Generally considered purer, without fermentation by-products
Cost Less expensive and produced in massive quantities More expensive and has a lower yield
Potential Risks Associated with allergic and inflammatory reactions in sensitive individuals Considered safe, with no reported inflammatory side effects
Common Use Ubiquitous in processed foods, drinks, and supplements Found in whole foods like citrus fruits

Conclusion

While citric acid is a widespread and generally safe food additive, it is important to distinguish between the natural form found in fruits and the manufactured version created via mold fermentation. The acidity of the additive, particularly when consumed in high quantities from processed foods and drinks, poses a clear risk of dental enamel erosion. For a small portion of the population, manufactured citric acid may trigger inflammatory or allergic responses, possibly linked to residual impurities from the manufacturing process. By being mindful of consumption, reading product labels, and practicing good dental hygiene, consumers can better manage their intake and minimize potential side effects associated with citric acid additive.

Learn more about food additive safety from Healthline

Frequently Asked Questions

Yes, citric acid can be harmful to your teeth if consumed frequently or in large amounts. It is highly acidic and can erode tooth enamel, the protective outer layer of your teeth, leading to increased sensitivity and a higher risk of cavities.

Yes, consuming large quantities of citric acid can cause gastrointestinal issues. This may include nausea, vomiting, an upset stomach, or abdominal pain.

Yes, although they have the same chemical structure, there is a key difference in their origin. Natural citric acid comes from fruits, while manufactured citric acid (MCA) is produced via fermentation using a mold called Aspergillus niger. Some reports suggest that residual impurities from the mold in MCA may cause inflammatory reactions in some people.

Allergic or inflammatory reactions to manufactured citric acid have been reported, although they are uncommon. Symptoms can include joint pain, muscle pain, and respiratory issues, which some researchers believe are linked to mold residues from the production process.

Manufactured citric acid is on the FDA's 'generally recognized as safe' (GRAS) list. However, this status was granted decades ago without extensive safety testing for modern consumption levels. Some experts and case reports suggest more research is needed, especially concerning the effects of chronic exposure.

You can protect your teeth by consuming acidic foods and drinks in moderation, using a straw for acidic beverages, and rinsing your mouth with water afterward. Waiting at least 30 minutes before brushing after an acidic meal can also help protect softened enamel.

Manufactured citric acid is used because it is significantly cheaper and can be mass-produced in much larger quantities than it can be extracted from natural fruits, meeting the high demand of the food and beverage industry.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.