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What Are the Side Effects of Mega Cal Calcium?

5 min read

Approximately 14% of people taking calcium supplements experience gastrointestinal issues like bloating and constipation, which can also be side effects of Mega Cal calcium. While intended to support bone health, like any supplement, Mega Cal can cause adverse effects if not taken correctly or if underlying health conditions are present.

Quick Summary

Mega Cal calcium can cause common side effects such as constipation and gas, with more serious risks like hypercalcemia possible at high doses. Understanding proper use and potential drug interactions is crucial for safe supplementation.

Key Points

  • Digestive Issues: Mega Cal can cause common side effects like constipation, gas, and bloating, particularly due to its calcium carbonate content.

  • Hypercalcemia Risk: Overdosing on calcium supplements can lead to abnormally high calcium levels in the blood, known as hypercalcemia, with symptoms like increased thirst, confusion, and nausea.

  • Potential Kidney Stones: High doses of calcium from supplements can increase the risk of developing kidney stones, especially in predisposed individuals.

  • Significant Drug Interactions: Mega Cal can interfere with the absorption and effectiveness of many prescription drugs, including certain antibiotics, thyroid medications, and blood pressure meds.

  • Proper Dosage is Key: To minimize side effects, split doses of calcium throughout the day and take no more than 500-600 mg at once for optimal absorption.

  • Consult a Professional: Always speak with a healthcare provider before starting Mega Cal or any new supplement to ensure it's appropriate for your health and won't interact with other medications.

In This Article

Common Digestive Side Effects

One of the most frequently reported side effects of calcium supplements like Mega Cal is gastrointestinal (GI) discomfort. The specific type of calcium salt used in a supplement can significantly influence the severity of these symptoms. Mega Cal, which includes a complex of calcium carbonate, citrate, malate, fumarate, and succinate, may still cause issues because calcium carbonate is notoriously associated with constipation.

Common GI-related issues include:

  • Constipation: This is the most common side effect reported, particularly with calcium carbonate formulations. Increasing fluid intake and dietary fiber can help manage this condition.
  • Gas and Bloating: Many individuals may experience a feeling of fullness, gas, or bloating, especially when first starting a supplement.
  • Upset Stomach: Nausea and general stomach upset can occur, though it is often mild and resolves with continued use or by taking the supplement with food.

The Risks of Excessive Calcium: Hypercalcemia

While Mega Cal can be an effective way to supplement your diet, taking too much can lead to a condition called hypercalcemia, where calcium levels in the blood become too high. This risk is heightened when exceeding the recommended dosage or if you are already consuming high amounts of dietary calcium. High calcium levels can impact multiple organs, including the heart and kidneys.

Serious signs of hypercalcemia that require immediate medical attention include:

  • Increased thirst and frequent urination.
  • Nausea, vomiting, and loss of appetite.
  • Unusual weakness, fatigue, or tiredness.
  • Bone pain.
  • Confusion, memory problems, or mental/mood changes.
  • Abnormal heart rhythms (arrhythmias).

Potential Complications: Kidney Stones and Cardiac Concerns

Beyond hypercalcemia, excessive or improper calcium supplementation can lead to more serious complications. The risk of developing kidney stones is a known concern, especially for individuals with a history of them. Drinking plenty of water is essential to help prevent stone formation. There is also some mixed research regarding the link between high-dose calcium supplements and heart disease, with some studies suggesting a possible increase in coronary artery calcification. This is why getting calcium primarily from dietary sources, and only supplementing as necessary under a doctor's supervision, is often recommended.

Important Drug Interactions

Calcium supplements can interact with a variety of medications, reducing their absorption or altering their effects. It is critical to inform your healthcare provider about all medications you are taking before starting a Mega Cal regimen.

Medications that may interact with calcium include:

  • Antibiotics: Specifically tetracycline and quinolone antibiotics. Calcium can bind to these drugs, preventing their absorption. They should be taken several hours apart.
  • Thyroid Medication: Levothyroxine, used to treat an underactive thyroid, can have its absorption reduced by calcium. A four-hour gap between doses is recommended.
  • Blood Pressure Medications: Diuretics (thiazide diuretics) and calcium channel blockers (like verapamil and diltiazem) can be affected. Thiazide diuretics, for example, increase calcium levels, and taking extra calcium could cause them to rise too high.
  • Bisphosphonates: These osteoporosis drugs should not be taken at the same time as calcium supplements, as calcium can interfere with their absorption.

Comparison of Calcium Forms

Not all calcium supplements are created equal. Mega Cal is a combination of different calcium salts, but comparing the most common forms highlights why some people may experience more side effects than others.

Feature Calcium Carbonate (in Mega Cal) Calcium Citrate (in Mega Cal)
Elemental Calcium High (approx. 40%) Lower (approx. 21%)
Absorption Best absorbed with food, requires stomach acid Absorbed well with or without food
Side Effects More likely to cause constipation, gas, and bloating Less likely to cause GI side effects
Ideal Users Individuals with sufficient stomach acid; those who don't experience GI issues Individuals with low stomach acid or sensitive stomachs

How to Safely Take Mega Cal

To minimize the risk of side effects and maximize the benefits of Mega Cal, consider these tips:

  1. Follow Dosage Guidelines: Adhere strictly to the recommended daily dosage or your doctor's specific instructions. Do not exceed the Tolerable Upper Intake Level (UL) for your age group.
  2. Split Doses: For better absorption and to reduce side effects like gas and bloating, take smaller doses (500 mg or less) throughout the day, rather than all at once.
  3. Take with Food: Calcium carbonate is best absorbed when taken with meals, which helps the stomach produce acid needed for absorption.
  4. Stay Hydrated: Drinking plenty of water can help prevent constipation and reduce the risk of kidney stones.
  5. Be Aware of Interactions: Separate your supplement intake from interacting medications by several hours as directed by your healthcare provider.

Conclusion: Consult Your Doctor

While Mega Cal can be a valuable supplement, its side effects can range from mild digestive upset to serious conditions like hypercalcemia and kidney stones if taken improperly or in excess. The potential for drug interactions also underscores the importance of medical supervision. A healthcare provider can help determine if Mega Cal is right for you, what dosage is appropriate, and how to manage potential side effects. Always prioritize a well-rounded diet, and use supplements as a tool under professional guidance, not as a replacement for whole foods. For further information on calcium requirements and supplement safety, consult reliable health resources like the National Institutes of Health.

Important Considerations for Safe Supplementation

To ensure safe and effective use, always communicate openly with your healthcare provider about all health conditions and other medications you are taking. This includes disclosing a history of kidney stones, heart disease, or parathyroid issues. They can help you determine the right supplement and schedule, and monitor your health for any adverse effects.


How Mega Cal Compares to Other Supplements

It is important to remember that Mega Cal is a proprietary blend. Different supplements, whether brand name or generic, will have different compositions and absorption rates. For instance, some may only contain calcium citrate, which is often better tolerated by those with sensitive digestive systems, though it contains less elemental calcium by weight than carbonate. The best approach is to discuss your specific needs with a doctor, who can recommend the most suitable option for you based on your diet, health history, and any existing medications. They may also suggest getting as much calcium as possible from dietary sources, reserving supplementation for when it's truly necessary.

Frequently Asked Questions

Mega Cal is a brand of calcium supplement, such as that offered by Jamieson, containing a blend of various calcium sources like carbonate, citrate, and malate, often combined with Vitamin D to aid absorption.

Yes, like many calcium supplements, Mega Cal can cause constipation. The calcium carbonate it contains is a known culprit for this common side effect.

Symptoms of excessive calcium intake, or hypercalcemia, include nausea, vomiting, increased thirst and urination, unusual weakness, bone pain, confusion, and abnormal heart rhythms.

Mega Cal should be taken with food. The calcium carbonate component in the supplement is best absorbed when consumed with a meal, which helps the body produce the necessary stomach acid.

Yes, taking high doses of calcium supplements can increase the risk of kidney stones, particularly in those with a history of them. Staying well-hydrated is a key preventive measure.

Yes, calcium can interfere with the absorption of certain medications, including some antibiotics, thyroid hormones (levothyroxine), and blood pressure drugs. It is crucial to separate the timing of doses.

Individuals with a history of kidney stones, hypercalcemia, certain heart conditions, or those taking specific interacting medications (e.g., digoxin) should consult a doctor before taking Mega Cal.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.