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What are the side effects of taking wheat germ?

4 min read

While wheat germ is a nutritional powerhouse rich in fiber and vitamins, it is also a concentrated source of certain compounds that can lead to adverse effects in some people. Being aware of these potential downsides is crucial for safe and beneficial consumption.

Quick Summary

Potential adverse reactions to wheat germ include digestive distress like nausea and diarrhea, allergic responses in sensitive individuals, and potential weight gain due to its high-calorie content. Certain medical conditions and medications also warrant caution.

Key Points

  • Gluten Warning: Wheat germ contains gluten and should be avoided entirely by individuals with celiac disease or gluten intolerance to prevent intestinal damage.

  • Digestive Distress: Common side effects include nausea, diarrhea, gas, and bloating, especially when introduced too quickly or consumed in large amounts.

  • Weight Gain Risk: Due to its high calorie and fat content, excessive wheat germ consumption can contribute to weight gain if not balanced with overall caloric intake.

  • Drug Interactions: Fermented wheat germ extract can interact with certain medications, including immunosuppressants and Vitamin C, and should be used with caution.

  • Allergic Reactions: Beyond gluten, wheat germ can cause allergic reactions in individuals with a wheat allergy, potentially leading to severe symptoms like anaphylaxis.

  • Kidney Stone Concern: The high oxalate content in wheat germ can increase the risk of calcium-oxalate kidney stones in susceptible individuals.

  • Contraindicated for Some: Wheat germ extract should be avoided by organ transplant recipients, and its use during pregnancy and breastfeeding is not well-studied and should be avoided.

In This Article

Introduction to Wheat Germ and Its Potential Issues

Wheat germ is the embryonic core of the wheat kernel, containing concentrated nutrients, vitamins, and fiber. While it's celebrated for its health benefits, including boosting heart health and immune function, it is not suitable for everyone. Its rich composition can be the cause of several side effects, particularly for those with sensitivities or underlying health conditions. The most common issues revolve around digestive problems, allergic reactions, and interactions with other health factors.

Gastrointestinal and Digestive Side Effects

One of the most frequently reported side effects of consuming wheat germ is digestive upset. For those unaccustomed to a high-fiber diet, introducing a large amount of wheat germ too quickly can overwhelm the digestive system. This can lead to a variety of uncomfortable symptoms.

Common Digestive Issues

  • Nausea and Diarrhea: The high fiber content in wheat germ can have a mild laxative effect. For some, this can cause stomach upset, leading to feelings of nausea or soft stools and diarrhea.
  • Gas and Bloating: As the body processes a sudden increase in fiber, gas production can increase, resulting in bloating and flatulence. This effect can be minimized by starting with a small dose and gradually increasing intake.
  • Constipation: Paradoxically, insufficient fluid intake while increasing fiber can lead to constipation instead of preventing it. The fiber absorbs water, and without enough hydration, stool can become dry and hard to pass.

Allergies, Intolerances, and Immune Responses

Because wheat germ is a component of wheat, it contains gluten and can trigger reactions in individuals with specific sensitivities or allergies. It is not a suitable supplement for those with celiac disease or gluten intolerance.

Adverse Reactions to Wheat Germ

  • Gluten Intolerance and Celiac Disease: Wheat germ contains gluten, the protein that triggers an autoimmune response in people with celiac disease. Ingesting wheat germ can cause significant intestinal damage and inflammation in these individuals.
  • Wheat Allergy: Distinct from celiac disease, a wheat allergy causes the immune system to produce antibodies to wheat proteins. Symptoms can include hives, swelling, congestion, or even life-threatening anaphylaxis.
  • Immunosuppressant Interference: Fermented wheat germ extract has been shown to potentially increase immune system activity. This can be a moderate risk for individuals on immunosuppressant medication, as it may reduce the drug's effectiveness. Consult a doctor before combining wheat germ with these medications.

Other Health Considerations

Beyond digestive and allergic issues, other factors make wheat germ a cautious addition to some diets.

High Calorie and Weight Gain Potential

While nutritious, wheat germ is calorie-dense. A single ounce contains over 100 calories. For individuals looking to manage or lose weight, adding wheat germ without adjusting overall caloric intake could lead to unintended weight gain.

Risk of Kidney Stones

Wheat germ is high in oxalates, natural compounds that can bind with calcium. For those predisposed to kidney stones, particularly calcium-oxalate stones, excessive intake could increase risk.

Contraindications and Interactions

Several conditions or situations warrant avoiding or carefully monitoring wheat germ intake.

  • Pregnancy and Breastfeeding: There is insufficient evidence regarding the safety of wheat germ extract for pregnant or breastfeeding women. It is best to avoid medicinal doses.
  • Organ Transplant Recipients: The potential for fermented wheat germ extract to increase immune system activity means it should be avoided by organ transplant recipients.
  • Specific Medications: Besides immunosuppressants, moderate interactions have been noted with ascorbic acid (Vitamin C) and rose hips, with manufacturers recommending a two-hour separation.

Comparison Table: Raw Wheat Germ vs. Fermented Wheat Germ Extract

Feature Raw Wheat Germ Fermented Wheat Germ Extract (Avemar)
Form Flakes or powder Powder, granules, or supplements
Gluten Content High; contains gluten May contain trace amounts; generally considered unsafe for celiacs
Common Side Effects Nausea, gas, bloating, diarrhea Nausea, diarrhea, soft stools
Immunosuppressant Interaction Low risk Moderate risk; increases immune activity
Dosage Guidance Start small and increase gradually Specific medicinal dosages used in studies; consult provider
Weight Gain Risk Yes, due to high calories Less of a concern due to lower, therapeutic doses
Medical Contraindications Celiac disease, wheat allergy Organ transplants, gluten sensitivity, fructose intolerance

Minimizing Risks and Side Effects

For most people, enjoying wheat germ can be a part of a healthy diet, provided a few precautions are taken.

  • Start Small and Go Slow: Begin with a small amount (e.g., one teaspoon) and gradually increase your intake over several weeks. This allows your digestive system to adapt to the higher fiber content.
  • Stay Hydrated: Drink plenty of water throughout the day to support healthy digestion and prevent constipation when increasing fiber intake.
  • Check for Sensitivities: If you have celiac disease, gluten intolerance, or a wheat allergy, avoid wheat germ completely.
  • Consult a Professional: If you are on medication, especially immunosuppressants, or have underlying health conditions, talk to your doctor before adding wheat germ or its extracts to your diet.
  • Store Properly: Wheat germ can go rancid quickly due to its high oil content. Store it in the refrigerator or freezer to maintain freshness.

Conclusion

While wheat germ is packed with nutritional benefits, it is not without potential side effects. Digestive issues like nausea, diarrhea, and bloating are common, especially when starting with a high dose. Individuals with gluten intolerance, celiac disease, or wheat allergies must avoid it entirely due to its gluten content. Furthermore, high calories can lead to weight gain, and interactions with certain medications, particularly immunosuppressants, exist. By being mindful of these risks, paying attention to portion sizes, and consulting a healthcare provider when necessary, most people can safely incorporate wheat germ into their diet. For anyone with a pre-existing condition or who experiences adverse symptoms, it's essential to prioritize caution and discontinue use if needed. For more information on wheat allergies and related conditions, you can consult reputable sources like the Mayo Clinic website.

Frequently Asked Questions

No, people with celiac disease should not eat wheat germ, as it contains gluten and will trigger an autoimmune response that damages the small intestine.

Yes, it can. The high fiber content can cause gas, bloating, and other digestive discomforts, particularly if your body is not used to a high-fiber diet.

Yes, wheat germ is calorie-dense. Consuming large quantities without adjusting your overall diet could lead to unwanted weight gain.

Yes, especially the fermented extract. It can interact with immunosuppressants, potentially decreasing their effectiveness. Interactions with ascorbic acid and rose hips have also been noted.

There is insufficient scientific evidence to confirm the safety of wheat germ extract for pregnant or breastfeeding women. It is best to avoid or consult a healthcare provider.

Individuals with celiac disease, gluten sensitivity, a wheat allergy, fructose intolerance, or those with organ transplants or on immunosuppressant drugs should avoid wheat germ.

Symptoms of a wheat allergy reaction can include swelling, hives, itching in the mouth or throat, nasal congestion, and in severe cases, anaphylaxis.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.