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What is Isosource HN? A Comprehensive Guide

4 min read

Isosource HN is a nutritionally complete, high-protein liquid formula providing 1.2 calories per mL, formulated for patients with normal or elevated energy and protein needs. This medical nutrition product supports lean body mass and is commonly used for short- or long-term tube feeding under medical supervision.

Quick Summary

Isosource HN is a high-protein, calorie-dense liquid formula for enteral tube feeding, formulated to provide complete nutrition for adults with elevated protein or calorie needs, or malnutrition. Its composition supports lean body mass.

Key Points

  • High-Nitrogen Formula: Isosource HN is a high-protein, nutritionally complete liquid formula providing 1.2 calories per mL for tube feeding.

  • Supports Lean Body Mass: Its high-quality casein and soy protein blend is specifically formulated to help maintain and support lean body mass.

  • For Elevated Needs: It is prescribed for patients with normal or elevated energy and protein requirements due to malnutrition, illness, or surgery.

  • Convenient and Ready-to-Use: The formula comes as a ready-to-use liquid in convenient cartons or closed systems for easy administration.

  • Not for IV Use: Isosource HN is strictly for enteral (tube) feeding and must not be administered intravenously.

  • Requires Medical Supervision: Its use is intended under the strict guidance and supervision of a healthcare professional.

In This Article

Understanding Isosource HN: More Than a Standard Formula

Isosource HN, which stands for "High Nitrogen," is a specialized medical formula designed for enteral feeding, where nutrition is delivered directly into the gastrointestinal tract via a feeding tube. Unlike standard nutritional supplements, its high-protein and calorie-dense profile is specifically tailored to meet the intensified nutritional demands of certain medical conditions. It is part of the Isosource product line developed by Nestlé Health Science and is meant for use under strict medical supervision. The high-quality blend of casein and soy protein is a cornerstone of its formulation, aiming to help support and maintain lean body mass in patients who are unable to meet their nutritional needs through oral intake alone.

Key Nutritional Components and Composition

Isosource HN's specific macronutrient breakdown is crucial to its efficacy. At 1.2 kcal/mL, it offers a concentrated source of energy in a smaller volume, which is particularly useful for patients with fluid restrictions. The formula's protein content is a high 18% of total calories, sourced from a blend of soy protein isolate, sodium caseinate, and calcium caseinate. This balanced protein mixture provides a complete amino acid profile essential for muscle repair and maintenance.

The carbohydrate sources, glucose syrup and maltodextrin, are easily digestible and contribute 52% of the formula's total caloric content. The fat component, making up 30% of the calories, comes primarily from canola oil, known for its monounsaturated fat content and ALA (an omega-3 fatty acid), and a portion of medium-chain triglycerides (MCTs) to aid in rapid and effective fat absorption. Additionally, Isosource HN is fortified with a full spectrum of essential vitamins and minerals, meeting or exceeding 100% of the Daily Recommended Intake for most key micronutrients in a 1250 mL volume.

Medical Indications for Isosource HN

Healthcare professionals often prescribe Isosource HN for specific clinical applications. Its primary uses include:

  • Elevated Protein Needs: Patients who require a higher-than-average protein intake due to conditions such as post-surgery recovery, wounds, or burns.
  • Malnutrition: Providing comprehensive nutritional support for individuals suffering from malnutrition or at risk of it.
  • Inadequate Oral Intake: A sole or supplemental source of nutrition for patients who cannot consume sufficient calories orally.
  • Fluid Restriction: The concentrated caloric density is advantageous for patients with limited fluid intake.
  • Transitional Feeding: Supporting patients as they transition from intravenous (IV) to enteral feeding.
  • Dysphagia: For individuals with difficulty swallowing who require tube-based nourishment.

Comparison of Isosource Formulas

While Isosource HN is a well-established formula, the Isosource product line has evolved. A newer product, Isosource 1.2, has replaced Isosource HN in some markets, and other versions, like Isosource Fibre, exist. Here is a comparison of key features:

Feature Isosource HN (Legacy) Isosource 1.2 (Newer) Isosource Fibre 1.5
Caloric Density 1.2 kcal/mL 1.2 kcal/mL 1.5 kcal/mL
Protein (% of kcal) 18% 18% 18%
Primary Fat Source Canola Oil, MCTs Canola Oil, MCTs Canola Oil, MCTs
Fiber Content Low-residue formula No fiber Yes (contains IS50™ fiber blend)
Lactose-Free Yes* Yes* Yes*
Gluten-Free Yes Yes Yes
Suitable Diets Kosher Kosher Kosher

Note: Not suitable for individuals with galactosemia.

Preparing and Administering Isosource HN

Isosource HN is designed for convenience as a ready-to-use liquid formula, available in cartons or closed feeding systems. It does not require dilution and can be administered at room temperature or chilled.

Best practices for administration include:

  • Storage: Unopened containers should be stored in a cool, dry place. Once opened, they must be refrigerated and used within 24 hours.
  • Shaking: Shake well before use to ensure all ingredients are properly mixed.
  • Not for IV Use: This formula is for enteral use only and should never be administered intravenously.
  • Medical Guidance: Always follow the feeding schedule and rate prescribed by a healthcare professional.

Potential Side Effects and Considerations

While generally well-tolerated, some patients may experience side effects, particularly related to the gastrointestinal system. These can include:

  • Bloating
  • Gas
  • Diarrhea
  • Constipation

Digestive issues may be related to a patient's individual tolerance or the rate of feeding. For those with milk or soy allergies, allergic reactions are possible. It is imperative to monitor patients for any adverse reactions and to follow a healthcare provider's recommendations for managing side effects. High protein intake may also place a strain on the kidneys for individuals with pre-existing renal conditions, a factor a doctor must consider before prescription.

Conclusion

Isosource HN serves a critical role in medical nutrition by providing a comprehensive, high-protein, and calorie-dense formula for patients who require enteral tube feeding. Its specific formulation supports lean body mass and addresses the heightened nutritional needs associated with various health conditions, from malnutrition to post-surgical recovery. While newer iterations and alternatives exist within the Isosource family, the core purpose of delivering complete and specialized nutrition remains the same. As with all medical nutritional products, its use is contingent on the oversight and guidance of a qualified healthcare professional. For more details on the product, you can visit the official Nestlé Medical Hub website.

Frequently Asked Questions

Isosource HN is a high-nitrogen, calorie-dense formula (1.2 kcal/mL), meaning it provides a higher concentration of protein and calories in a smaller volume than many standard formulas. This makes it suitable for patients with elevated protein needs or fluid restrictions.

While primarily designed for tube feeding, some versions of the Isosource product line are also suitable for oral consumption. However, Isosource HN is typically used for enteral feeding, and any oral use should be discussed with a healthcare provider.

Yes, Isosource HN is formulated to be lactose-free and is suitable for individuals with lactose intolerance. However, it is not for those with galactosemia.

The formula contains both milk (sodium and calcium caseinate) and soy (soy protein isolate), which are common allergens. Individuals with allergies to milk or soy should avoid this product.

Unopened containers of Isosource HN should be stored at room temperature. Once opened, any unused formula must be covered, refrigerated, and used within 24 hours to ensure safety.

Due to its high carbohydrate content (glucose syrup, maltodextrin), Isosource HN may not be suitable for individuals with insulin resistance or diabetes. A healthcare provider should be consulted to determine the most appropriate formula for diabetic patients.

Potential side effects include digestive issues like bloating, gas, diarrhea, and constipation. Allergic reactions are also possible, especially in individuals with milk or soy allergies. Any adverse effects should be reported to a healthcare professional.

Isosource HN is a complex nutritional formula with a high concentration of macronutrients that can only be safely absorbed and processed by the gastrointestinal system. Intravenous (IV) use, also known as parenteral administration, requires a different type of formula and carries significant risks if not followed correctly.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.