Skip to content

What is the benefit of calcium glycinate? A guide to superior absorption

4 min read

Did you know that the absorption rate of calcium supplements can vary significantly, with some forms being up to 1.8 times more bioavailable than others? The key to maximizing your calcium intake might lie in understanding what is the benefit of calcium glycinate, a chelated supplement designed for superior absorption and digestive comfort.

Quick Summary

Calcium glycinate is a chelated form of calcium that provides superior bioavailability and absorption compared to other common forms like carbonate. It effectively supports bone density, reduces osteoporosis risk, and is gentler on the digestive system, making it an excellent choice for individuals with sensitive stomachs.

Key Points

  • Superior Absorption: Calcium glycinate is a chelated form, making it significantly more bioavailable and easier for the body to absorb than common alternatives like calcium carbonate.

  • Bone Health: High absorption effectively supports bone mineral density, which is crucial for preventing osteoporosis and maintaining overall skeletal strength.

  • Gentle on Digestion: Its chelated nature means calcium glycinate causes fewer gastrointestinal side effects like constipation and bloating compared to less expensive calcium salts.

  • Nervous System Support: The glycine component provides additional benefits, acting as a calming amino acid that supports a healthy nervous system and muscle function.

  • Optimal Intake: For better absorption, it may be beneficial to take calcium in smaller, split amounts if your daily needs are high.

  • Ideal for Some Conditions: It is an excellent choice for individuals with low stomach acid, inflammatory bowel disease, or a sensitive digestive tract.

In This Article

Before considering calcium glycinate or any dietary supplement, it is important to consult with a healthcare professional to determine if it is appropriate for your individual needs and to discuss potential benefits, risks, and proper usage.

What is Chelation? The Key to Calcium Glycinate's Advantage

Calcium glycinate, or calcium bisglycinate, is a chelated form of calcium. The term "chelate" refers to a chemical process where a mineral, in this case, calcium, is bonded to an amino acid, glycine. This unique bonding process creates a more stable molecule that is recognized and transported more efficiently through the intestinal wall, leading to higher absorption.

Unlike standard calcium salts, the chelated structure protects the calcium from interactions with stomach acid and other nutrients that could otherwise inhibit absorption. This makes calcium glycinate particularly effective for individuals with low stomach acid, a condition common among older adults.

The Primary Benefits of Supplementing with Calcium Glycinate

The chelated structure of calcium glycinate translates into several key health benefits, distinguishing it from less bioavailable alternatives.

  • Superior Bioavailability and Absorption: Studies suggest that calcium glycinate is one of the most soluble and best-absorbed forms of supplemental calcium available. It has been shown to be more effective than both calcium carbonate and calcium citrate, ensuring more of the mineral reaches your bones and tissues.
  • Enhanced Bone Health and Osteoporosis Prevention: Calcium is fundamental for building and maintaining strong bones, and over 99% of the body's calcium is stored in the skeletal system. The high absorption rate of calcium glycinate allows for more effective mineral deposition, which is crucial for increasing bone mineral density and reducing the risk of osteoporosis and fractures.
  • Minimal Gastrointestinal Side Effects: Many people experience constipation, gas, or bloating with calcium carbonate supplements. Calcium glycinate is notably gentler on the digestive system, as the body processes the mineral-amino acid chelate more smoothly, minimizing digestive distress.
  • Supports Muscle and Nervous System Function: Beyond bone health, calcium is vital for proper muscle contraction and nerve signal transmission. The glycine component of this supplement also acts as a calming amino acid and neurotransmitter, supporting overall nervous system health.
  • Contributes to Cardiovascular Health: Calcium plays a role in the function of the heart muscle and in regulating blood pressure. The improved absorption of calcium glycinate ensures that these systems receive the necessary mineral support.

Comparing Calcium Glycinate with Common Alternatives

When choosing a calcium supplement, it's essential to understand the differences in bioavailability and tolerability between the most common forms.

Feature Calcium Glycinate Calcium Citrate Calcium Carbonate
Bioavailability High; significantly higher than citrate and carbonate Moderate; better than carbonate, but less than glycinate Low; requires stomach acid for absorption
Dependence on Food Does not depend on stomach acid; can be taken with or without food Less dependent on food; can be taken anytime Must be taken with food for adequate absorption
GI Side Effects Minimal; known for being gentle on the stomach Less likely to cause GI upset than carbonate Higher risk of constipation, gas, and bloating
Cost Premium; typically more expensive Moderate Economical; typically the least expensive
Absorption Mechanism Chelate structure aids efficient intestinal uptake Organic salt absorbed well, especially with food Inorganic salt relies on stomach acid for dissolution and absorption

Optimal Usage and Considerations

Who Should Consider Calcium Glycinate?

This supplement is a valuable option for several groups of people:

  • Postmenopausal women who are at a higher risk for bone density loss.
  • Individuals with low stomach acid (achlorhydria), as its absorption is not dependent on gastric acid.
  • Those with digestive issues like inflammatory bowel disease (IBD) or a history of gastric bypass surgery, which can affect nutrient absorption.
  • Anyone sensitive to other forms of calcium who experiences uncomfortable side effects like constipation or bloating.
  • Individuals on a vegan diet or who avoid dairy and need an effective calcium source.

Proper Usage

To maximize the effectiveness of any calcium supplement, including calcium glycinate, consider the following guidelines:

  • Splitting Intake: The body's ability to absorb calcium at one time is limited. If your total daily recommended intake is more than this amount, splitting the intake into two or more servings throughout the day may be beneficial.
  • Timing with Other Nutrients: Taking calcium supplements separately from other minerals like iron and zinc by a few hours may be advisable as they can compete for absorption.
  • Avoiding Excessive Intake: While essential, consuming more calcium than recommended daily intakes from all sources combined can lead to potential health risks. Adhering to guidelines and consulting a healthcare professional is important.

Conclusion

Calcium glycinate stands out as a highly effective calcium supplement due to its superior bioavailability and gentle effect on the digestive system. By leveraging the process of chelation, it offers a more efficient path for the body to absorb and utilize this vital mineral, directly supporting stronger bones, better muscle function, and a healthier nervous system. While it may be a more premium option, the enhanced absorption and reduced side effects provide significant value for those seeking to optimize their calcium intake, particularly individuals with specific dietary or digestive sensitivities. As with any supplement, it is best to consult a healthcare professional to determine if calcium glycinate is the right choice for your nutritional needs.

Visit the NIH Office of Dietary Supplements for more information on calcium and health.

Frequently Asked Questions

Yes, calcium glycinate is known for its superior bioavailability and absorption. It has been shown to be better absorbed than both calcium carbonate and calcium citrate due to its chelated structure.

Calcium glycinate is less likely to cause constipation and other digestive issues like gas and bloating compared to calcium carbonate. Its chelated form is gentler on the digestive tract.

Calcium glycinate is a chelated form that offers superior absorption and is less likely to cause GI side effects. Calcium carbonate is an inorganic salt that is less expensive but requires stomach acid for proper absorption and more frequently causes digestive upset.

People with insufficient dietary calcium, individuals at high risk for osteoporosis (especially postmenopausal women), those with low stomach acid, and anyone with sensitive digestion should consider calcium glycinate.

Yes, by providing a highly absorbable source of calcium, glycinate can effectively help maintain bone mineral density and reduce the risk of osteoporosis, especially when combined with vitamin D.

While individual needs vary, splitting calcium intake throughout the day may aid absorption. Consulting a healthcare professional is recommended for personalized advice.

The calcium and glycine components of calcium glycinate are not derived from animal products, making the supplement suitable for vegan and vegetarian diets. Always check the supplement's inactive ingredients to ensure they meet your dietary standards.

Calcium supplements can interact with certain medications, including thyroid hormones and some antibiotics. It is important to consult your doctor or pharmacist to ensure proper timing and avoid drug interactions.

References

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
  7. 7
  8. 8
  9. 9
  10. 10

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.