Skip to content

What is the Best Form of Copper Supplement to Take?

4 min read

While severe copper deficiency is uncommon, certain health conditions or long-term high-dose zinc supplementation can compromise copper status. For those requiring additional intake, knowing what is the best form of copper supplement to take is crucial for effective and safe mineral absorption.

Quick Summary

Copper bisglycinate is considered the most highly absorbable form due to its chelated structure, while other forms like citrate and oxide offer varying degrees of bioavailability.

Key Points

  • Bisglycinate Is Best for Absorption: Copper bisglycinate, a chelated form, has high bioavailability and is the most recommended copper supplement for effective absorption.

  • Avoid Copper Sulfate: Copper sulfate is toxic and should never be ingested as a supplement.

  • Bioavailability Varies Greatly: Not all copper forms are equal; forms like copper oxide have poor utilization by the body, making them a less effective choice.

  • Balance Copper and Zinc: Long-term, high-dose zinc supplementation can lead to copper deficiency by inhibiting its absorption, highlighting the importance of balanced intake.

  • Food Sources are Key: For those who don't need supplements, excellent dietary sources of copper include shellfish, liver, nuts, and dark chocolate.

  • Be Mindful of Toxicity: Excess copper can be harmful. The tolerable upper intake level (UL) for adults is 10 mg per day.

  • Consult a Doctor: Individuals with certain genetic disorders, like Wilson's disease, must avoid copper supplements unless directed by a doctor.

In This Article

Why Copper is an Essential Mineral

Copper is a trace mineral that plays a vital role in numerous physiological processes. Despite only being needed in small amounts, its functions are extensive and critical for overall health.

Key roles of copper include:

  • Energy Production: It is a cofactor for enzymes that produce energy at the cellular level.
  • Iron Metabolism: Copper works with iron to help the body form red blood cells and effectively transport iron throughout the body.
  • Connective Tissue Formation: It is essential for the formation of collagen and elastin, which maintain the strength of connective tissues in bones, blood vessels, and the heart.
  • Antioxidant Defense: Copper is a component of the antioxidant enzyme superoxide dismutase, which helps protect cells from oxidative stress and free radical damage.
  • Immune Function: Proper copper levels support the immune system and prevent neutropenia, a low white blood cell count.

Understanding Bioavailability

Bioavailability refers to the proportion of a nutrient that is absorbed from the diet or a supplement and used by the body. For copper, which is naturally hard to absorb, bioavailability is a key factor in choosing an effective supplement. Different forms of copper have varying absorption rates, which is why the source of the mineral is so important. Chelated forms, for example, are minerals bound to an amino acid, which can improve absorption by allowing them to be transported through the intestinal wall more easily.

Forms of Copper Supplements Compared

Copper supplements are available in several forms, each with distinct absorption characteristics. The following table provides a comparison of the most common types.

Form of Copper Bioavailability Common Uses Notes
Copper Bisglycinate High General supplementation, improving absorption A chelated form bound to glycine, often considered the most absorbable. Good for those with potential absorption issues.
Copper Gluconate Medium to High General supplementation A chelated form widely available for oral use, though some studies show inconsistent effects.
Copper Citrate Variable Common and inexpensive general supplementation Bioavailability may be lower or inconsistent for some individuals compared to chelated forms.
Copper Sulfate None (Toxic) Industrial use, not for human consumption WARNING: This form is a toxin and should NEVER be ingested as a supplement.
Copper Oxide Poor Often included in multivitamins Considered poorly utilized and minimally absorbed by the body.
Copper Hydrosol Variable (Claims High) High-end, often liquid, supplements Some brands claim high bioavailability by offering a mix of copper states, though more research may be needed.

The Verdict: The Best Option for Most

Based on current research and expert consensus, copper bisglycinate stands out as the best form of copper supplement to take for optimal absorption. Its chelated structure ensures it is well-tolerated and effectively absorbed by the body, even for individuals with compromised gut lining or general absorption issues. This makes it a more reliable choice than common but potentially less bioavailable forms like copper citrate or the poorly absorbed copper oxide. For those looking to increase their copper levels safely and efficiently through supplementation, a product containing bisglycinate is the superior option.

Risks, Interactions, and Considerations

While copper is essential, excessive intake can lead to toxicity, which can cause severe side effects like liver damage and digestive distress. The tolerable upper intake level (UL) for adults is 10 mg per day from all sources, including food and supplements. Anyone with a genetic condition like Wilson's disease should avoid copper supplements unless under strict medical supervision.

Furthermore, copper interacts significantly with other minerals, particularly zinc. Long-term, high-dose zinc supplementation can induce a copper deficiency by hindering its absorption. Therefore, it is wise to balance supplementation or take copper and zinc at separate times to ensure proper absorption of both. If you are supplementing with zinc, it is a good practice to take a copper supplement as well to maintain a healthy balance. For individuals without a diagnosed deficiency, a balanced diet rich in copper-containing foods is often sufficient.

Food Sources Rich in Copper

Before reaching for a supplement, consider incorporating more copper-rich foods into your diet. Excellent sources include:

  • Oysters and other shellfish
  • Beef liver
  • Nuts (cashews, pecans) and seeds (sunflower, sesame)
  • Dark chocolate
  • Whole grains and legumes
  • Potatoes, mushrooms, and avocados

Conclusion

In summary, while dietary intake from nutrient-dense foods like liver, shellfish, nuts, and seeds is the preferred route for most, those with specific needs or deficiencies often require supplementation. When choosing a supplement, the bioavailability of the form is paramount. The chelated form, copper bisglycinate, is the best form of copper supplement to take due to its superior absorption and tolerability. In contrast, forms like copper oxide are poorly utilized, and the highly toxic copper sulfate must be avoided. Remember to adhere to recommended dosages and consult a healthcare professional to determine if supplementation is necessary for you. For more detailed information on mineral requirements, visit the NIH Office of Dietary Supplements website.

NIH Office of Dietary Supplements - Copper

Navigating Your Supplement Choices

To ensure you are choosing the right copper supplement, prioritize those with high bioavailability to maximize the benefits. Copper bisglycinate is the most reliable option for absorption and tolerability. Always check the supplement label to identify the specific form of copper used, and avoid products containing the toxic copper sulfate. For anyone taking a high dose of zinc, a balanced copper supplement is particularly important to prevent deficiency. Prioritizing whole-food sources of copper is the best way to maintain healthy levels for those without a diagnosed deficiency.

The Final Word on Copper Intake

Whether through diet or supplementation, proper copper intake is essential for maintaining robust health across multiple systems, from energy production to immune function. The choice of supplement form, however, significantly impacts its effectiveness. By selecting highly bioavailable forms like copper bisglycinate, you can ensure your body is receiving and utilizing this crucial trace mineral efficiently. As with any supplement, consulting a healthcare provider is recommended, especially when managing pre-existing conditions or concurrent mineral intake.

Frequently Asked Questions

Copper bisglycinate, a chelated form, is widely considered the most easily and effectively absorbed copper supplement due to its structure, which allows it to be transported across the intestinal wall efficiently.

Copper citrate is a common and affordable form of copper supplement, but its bioavailability can be variable, meaning some individuals may not absorb it as effectively as other forms, such as bisglycinate.

Copper bisglycinate is better because it is a chelated mineral bound to the amino acid glycine, which improves its bioavailability and allows for better absorption and tolerability compared to non-chelated or inorganic forms.

Yes, long-term high-dose zinc supplementation can interfere with copper absorption and lead to a copper deficiency. It is important to balance intake or take these minerals at different times.

Symptoms of acute copper toxicity can include nausea, vomiting, bloody diarrhea, stomach pain, fever, and liver damage. Chronic toxicity can cause liver and kidney damage.

The tolerable upper intake level (UL) for copper for adults is 10 mg per day, including intake from all sources like food, water, and supplements.

While colloidal copper is a form of supplement, there is insufficient evidence to show it is superior to other forms like bisglycinate. For skin application, topical use has shown some benefits, but internal use requires more research.

References

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.