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What Is the Best Supplement to Take During a Workout?

5 min read

Research consistently shows that supplementing with certain nutrients at the right time can significantly enhance athletic performance, reduce fatigue, and speed up recovery. This guide will help you determine what is the best supplement to take during a workout, based on your training intensity and fitness objectives.

Quick Summary

This guide covers the top science-backed intra-workout supplements, including BCAAs, electrolytes, carbohydrates, and creatine. It details the unique benefits of each to help you select the ideal option for maximizing performance and recovery during exercise.

Key Points

  • Goal-Oriented Supplementation: The best intra-workout supplement depends entirely on your training objective, such as strength, endurance, or hypertrophy.

  • Amino Acids for Muscle Protection: BCAAs or, more comprehensively, EAAs help prevent muscle breakdown during long or intense sessions, especially when training fasted.

  • Carbohydrates for Fuel: Fast-absorbing carbs are crucial for replenishing glycogen stores and sustaining high-volume or endurance performance beyond 60 minutes.

  • Electrolytes for Hydration: Replacing electrolytes lost through sweat is vital for preventing cramps and dehydration during prolonged or intense exercise.

  • Creatine for Explosive Power: For strength training, creatine helps maximize explosive power by rapidly replenishing ATP stores in the muscles.

  • Nitrates for Endurance: Compounds from beetroot juice can improve oxygen delivery and efficiency, benefiting endurance athletes.

  • Hydration is Key: Supplements are secondary to proper hydration with plain water or a balanced electrolyte drink during any workout.

In This Article

Understanding the Concept of Intra-Workout Supplementation

The goal of intra-workout nutrition is to provide your body with the fuel and building blocks it needs to sustain performance throughout your training session. Unlike pre-workout supplements that primarily boost energy and focus, or post-workout products that focus on recovery, intra-workout supplements are designed to be consumed during the exercise itself. This is most beneficial for longer, more intense training sessions lasting 60 minutes or more.

For many casual gym-goers, simple water is sufficient, especially if their diet is already well-structured. However, for serious athletes or those pushing their limits, specific supplements can provide a significant performance edge. The key is to match the supplement to your workout type and duration.

Intra-Workout Supplements for Different Goals

The best intra-workout fuel depends heavily on your training objective. A marathon runner has different needs than a weightlifter.

For Strength and Hypertrophy

  • Branched-Chain Amino Acids (BCAAs) and Essential Amino Acids (EAAs): Comprising leucine, isoleucine, and valine, BCAAs are crucial for stimulating muscle protein synthesis and preventing muscle breakdown during intense sessions. EAAs provide a more complete profile of all nine essential amino acids, which is even more effective for muscle repair and growth. Sipping a BCAA or EAA formula can protect muscles, especially when training in a fasted state.
  • Creatine: While often associated with pre- or post-workout use, creatine can be included in an intra-workout shake to further saturate muscle creatine stores. This helps replenish adenosine triphosphate (ATP), the primary energy source for quick, explosive movements, allowing for greater power and strength output during lifting sets.
  • Fast-Acting Carbohydrates: For higher-volume lifting sessions, fast-absorbing carbohydrates like dextrose or cyclic dextrin can prevent a drop in blood sugar and energy levels. These carbs replenish muscle glycogen, allowing for sustained high-intensity output.

For Endurance and Stamina

  • Electrolytes: Sodium, potassium, magnesium, and calcium are essential for nerve function, muscle contractions, and maintaining fluid balance. When you sweat, you lose electrolytes, and replenishing them during endurance events lasting over 60 minutes is critical to preventing dehydration and muscle cramps. A balanced electrolyte drink is far superior to plain water for prolonged exercise.
  • Fast-Absorbing Carbohydrates: As mentioned above, carbs are paramount for endurance sports. They provide readily available energy to fuel working muscles and prevent fatigue. Many sports drinks and gels are designed specifically for this purpose, providing a quick energy source without causing digestive distress.
  • Nitrates (from Beetroot Juice): Dietary nitrates, found in beetroot juice, are converted into nitric oxide in the body, which improves blood flow and oxygen delivery to muscles. This can enhance endurance and reduce the oxygen cost of exercise. Taking a concentrated beetroot shot 2–3 hours before a long endurance session is a popular strategy among athletes.

The All-in-One Approach and Hydration

Many intra-workout products are now formulated to cover multiple needs by combining several key ingredients into one convenient powder. These blends often feature a mix of amino acids (EAAs or BCAAs), electrolytes, and sometimes a fast-acting carb source. This simplifies the process for athletes who want a comprehensive performance and hydration solution in one bottle.

However, it’s important to read the ingredient list and understand the dosages. Some products may contain minimal amounts of key ingredients, so selecting a high-quality, scientifically dosed product is essential. Regardless of your chosen supplement, maintaining proper hydration is the most fundamental aspect of intra-workout nutrition. The supplement is an add-on, not a replacement for water.

Supplement Comparison Table

Supplement Best For Primary Benefit Timing Key Considerations
EAAs/BCAAs Strength, Hypertrophy, Fasted Cardio Prevents muscle breakdown, promotes recovery Sip throughout workout Ensure adequate protein intake overall for EAAs
Creatine Strength, Explosive Power, HIIT Boosts ATP for maximal effort Can be added to intra-workout drink Needs consistent, daily intake for saturation
Fast-Carbs High-Volume Training, Endurance Sustains energy, replenishes glycogen Sip throughout long/intense sessions Can cause crashes if over-dosed; avoid high sugar
Electrolytes Endurance, High-Sweat Sessions Maintains hydration, prevents cramps Sip throughout workout Essential for workouts over 60 minutes
Nitrates Endurance, Aerobic Efficiency Improves oxygen delivery to muscles 2-3 hours pre-workout Requires loading phase for consistent effect

Conclusion: Tailoring Your Approach

Ultimately, there is no single "best" supplement for every workout. The ideal choice depends on your specific goals, the intensity and duration of your training, and your individual needs. For a quick strength session under 60 minutes, focusing on proper pre-workout nutrition might be enough. For a longer, more grueling workout, an intra-workout drink with a combination of electrolytes and fast-acting carbohydrates can be a game-changer. For those specifically aiming to prevent muscle catabolism, a BCAA or EAA supplement can offer valuable support.

Before incorporating any new supplement into your routine, it is always recommended to consult with a healthcare or fitness professional, especially if you have underlying health conditions or are taking other medications. The market for sports nutrition is vast, but understanding the science behind the most effective ingredients will empower you to make an informed decision that truly helps you meet your fitness goals.

To learn more about the science of sports nutrition, visit the International Society of Sports Nutrition (ISSN) website.

Frequently Asked Questions

What is the most effective intra-workout supplement for muscle growth?

For muscle growth, a combination of fast-acting carbohydrates and essential amino acids (EAAs), particularly leucine, is highly effective during a workout to prevent muscle breakdown and fuel protein synthesis.

Do I really need an intra-workout supplement?

For short-duration or low-intensity workouts, probably not. However, for intense sessions lasting longer than 60 minutes or high-volume training, supplementing can help maintain energy levels, prevent muscle fatigue, and accelerate recovery.

What are electrolytes and why do I need them during exercise?

Electrolytes are essential minerals like sodium, potassium, and magnesium that you lose through sweat. They are crucial for nerve function, muscle contraction, and maintaining proper hydration, especially during long, intense, or hot-weather workouts.

Is it better to take BCAAs or EAAs during a workout?

While BCAAs are popular for muscle preservation, EAAs are generally considered more comprehensive because they provide a complete amino acid profile, offering better overall support for muscle repair and protein synthesis.

Can I just use a sports drink instead of a dedicated intra-workout supplement?

Many traditional sports drinks contain carbohydrates and electrolytes, which can be beneficial. However, dedicated intra-workout products often provide a more optimal balance of fast-absorbing carbs, electrolytes, and amino acids tailored for performance, with less sugar.

How does creatine help during a workout?

When taken consistently, creatine helps increase the body's store of phosphocreatine, which is used to rapidly produce ATP during high-intensity, short-duration activities like lifting heavy weights. This can lead to more reps and increased strength over time.

Are there any supplements I should avoid taking during a workout?

Certain stimulant-heavy supplements, especially those high in caffeine, should be used with caution, as high doses can cause jitters or gastrointestinal discomfort in some individuals. Also, avoid large amounts of slow-digesting proteins or high-fat meals during a workout, as they can cause stomach upset.

Frequently Asked Questions

For muscle growth, a combination of fast-acting carbohydrates and essential amino acids (EAAs), particularly leucine, is highly effective during a workout to prevent muscle breakdown and fuel protein synthesis.

For short-duration or low-intensity workouts, probably not. However, for intense sessions lasting longer than 60 minutes or high-volume training, supplementing can help maintain energy levels, prevent muscle fatigue, and accelerate recovery.

Electrolytes are essential minerals like sodium, potassium, and magnesium that you lose through sweat. They are crucial for nerve function, muscle contraction, and maintaining proper hydration, especially during long, intense, or hot-weather workouts.

While BCAAs are popular for muscle preservation, EAAs are generally considered more comprehensive because they provide a complete amino acid profile, offering better overall support for muscle repair and protein synthesis.

Many traditional sports drinks contain carbohydrates and electrolytes, which can be beneficial. However, dedicated intra-workout products often provide a more optimal balance of fast-absorbing carbs, electrolytes, and amino acids tailored for performance, with less sugar.

When taken consistently, creatine helps increase the body's store of phosphocreatine, which is used to rapidly produce ATP during high-intensity, short-duration activities like lifting heavy weights. This can lead to more reps and increased strength over time.

Certain stimulant-heavy supplements, especially those high in caffeine, should be used with caution, as high doses can cause jitters or gastrointestinal discomfort in some individuals. Also, avoid large amounts of slow-digesting proteins or high-fat meals during a workout, as they can cause stomach upset.

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.