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What is the management of severe acute malnutrition?

4 min read

Severe acute malnutrition (SAM) affects millions of children under five globally and is a leading cause of childhood mortality. However, effective, phased management strategies have dramatically improved survival rates.

Quick Summary

The management of severe acute malnutrition involves a phased approach: initial stabilization for critically ill patients, followed by a nutritional rehabilitation phase, and finally, outpatient care. Management protocols include medical treatment of complications, rehydration, and therapeutic feeding based on appetite and clinical condition.

Key Points

  • Triage is crucial: The management pathway for severe acute malnutrition (SAM) depends on the child's clinical status and presence of medical complications, determining if they need inpatient or outpatient care.

  • Stabilization first: For complicated cases, hospital-based care focuses on correcting life-threatening conditions like hypoglycaemia, hypothermia, and infection before aggressive feeding begins.

  • Therapeutic feeding is phased: Nutritional treatment starts with a lower-protein, lower-energy formula (F-75) during stabilization, transitioning to a higher-energy formula (F-100) or Ready-to-Use Therapeutic Food (RUTF) for rehabilitation.

  • Community-based management is effective: Most children with uncomplicated SAM can be treated at home with RUTF and a course of oral antibiotics, supported by regular clinic visits.

  • Infection is always assumed: Due to compromised immunity, broad-spectrum antibiotics are given routinely to all children with complicated SAM, even without obvious signs of infection.

  • Electrolytes require careful correction: Fluid and electrolyte imbalances, particularly low potassium and magnesium, are addressed with specially formulated rehydration solutions like ReSoMal, not standard ORS or diuretics.

  • Early stimulation is vital: Providing a stimulating and caring environment throughout the treatment process is important for the child's emotional and sensory development.

In This Article

Understanding the Management Approach to Severe Acute Malnutrition (SAM)

The management of severe acute malnutrition (SAM) is a critical public health priority, guided by evidence-based protocols developed by organizations like the World Health Organization (WHO). The approach is not one-size-fits-all but depends on the child's clinical condition, specifically the presence of medical complications and appetite. The treatment pathway is divided into distinct phases to ensure the child's safety and promote effective recovery. It is a nuanced process that moves from urgent medical stabilization to nutritional rehabilitation and long-term follow-up.

Screening and Triage: Inpatient vs. Outpatient Care

The first step in the management of severe acute malnutrition is a thorough clinical assessment to determine the appropriate care setting. This triage process is vital for separating those who can be treated at home from those requiring intensive hospital care.

Criteria for Inpatient Admission

Children are admitted for inpatient care if they present with specific complications that pose an immediate risk to their lives. These include:

  • Loss of appetite (failing the appetite test).
  • Severe oedema (swelling) of both feet, especially if it extends to the face and limbs.
  • Signs of medical complications, such as shock, hypothermia, hypoglycaemia, severe anemia, or pneumonia.
  • Altered mental status, including lethargy or unconsciousness.
  • Presence of other life-threatening conditions like severe dehydration or sepsis.

Criteria for Outpatient Management

Children with uncomplicated SAM can be managed at home through community-based programs (CMAM). They must meet the following criteria:

  • Good appetite (passing the appetite test).
  • No medical complications present.
  • No or mild oedema (without other complications).
  • Clinically alert and well.

The Three Phases of Inpatient Management

For children requiring hospital admission, the World Health Organization outlines a detailed 10-step approach, divided into three phases: stabilization, transition, and rehabilitation.

Phase 1: Stabilization (1-7 days)

The initial phase focuses on treating immediate life-threatening complications while managing metabolic and physiological disturbances.

  1. Treating and Preventing Hypoglycaemia: Small, frequent feeds with 10% glucose or sucrose are given immediately upon admission.
  2. Treating and Preventing Hypothermia: The child must be kept warm, often using skin-to-skin contact with the mother.
  3. Managing Dehydration: Rehydration is done slowly using a special low-sodium oral rehydration solution (ReSoMal) rather than standard ORS, to avoid fluid overload.
  4. Correcting Electrolyte Imbalance: Severely malnourished children have deficiencies in potassium and magnesium. These are corrected with supplementation, and no diuretics are used for oedema.
  5. Treating Infections: A broad-spectrum antibiotic is administered because signs of infection are often masked.
  6. Providing Micronutrients: High-dose vitamin A is given on day 1 if there are eye signs or a history of measles. Other micronutrients like zinc and folic acid are also supplemented, but iron is withheld until the rehabilitation phase.
  7. Initiating Feeding Carefully: Small, frequent feeds of a therapeutic formula, such as F-75, are given to restore metabolic function without overwhelming the system.

Phase 2: Transition (2-3 days)

This is a short period to move the child from the initial stabilizing formula to one that promotes rapid catch-up growth. F-75 is gradually replaced with F-100 or Ready-to-Use Therapeutic Food (RUTF) over a few days.

Phase 3: Rehabilitation (Several weeks)

This phase focuses on aggressive nutritional recovery and catch-up growth once the child is clinically stable and has regained their appetite.

  1. Catch-up Feeding: High-energy and high-protein therapeutic foods like RUTF are provided ad libitum (as much as the child wants).
  2. Sensory Stimulation: Providing a loving and playful environment is essential for the child's emotional and sensory development.
  3. Preparing for Follow-up and Discharge: Caregivers are educated on proper feeding practices, hygiene, and danger signs before the child is discharged to outpatient care.

Outpatient Treatment: Community-Based Management

For children with uncomplicated SAM, Community-Based Management of Acute Malnutrition (CMAM) is the recommended approach.

  • Children are provided with a supply of Ready-to-Use Therapeutic Food (RUTF), a high-energy paste that can be administered at home.
  • A short course of oral antibiotics (e.g., amoxicillin) is also prescribed to prevent infections.
  • Regular follow-up with a health worker at a local clinic ensures progress is monitored and any complications are addressed promptly.

Inpatient vs. Outpatient Management: A Comparison

Feature Inpatient Management (for complicated SAM) Outpatient Management (for uncomplicated SAM)
Location Hospital or Stabilisation Center Community clinic or home
Patient Condition Poor appetite, severe oedema, medical complications Good appetite, no medical complications
Medical Care Intensive, with monitoring for hypoglycemia, hypothermia, and infection Basic medical care, typically oral antibiotics
Feeding Formula F-75 (stabilization), then F-100 or RUTF (rehabilitation) Ready-to-Use Therapeutic Food (RUTF)
Monitoring Close monitoring of vital signs, fluid balance, and weight gain Periodic follow-up visits to a health worker
Key Focus Immediate survival and correction of metabolic issues Rapid nutritional rehabilitation and catch-up growth

Conclusion

The effective management of severe acute malnutrition is a multi-stage process that combines immediate life-saving care with structured nutritional rehabilitation and community support. By distinguishing between complicated and uncomplicated cases, modern protocols based on WHO guidelines ensure that children receive the right level of care, whether in a hospital or through community-based programs. This comprehensive strategy, utilizing specialized therapeutic foods and targeted medical interventions, has been instrumental in reducing the high mortality rates associated with SAM and improving long-term outcomes for vulnerable children. Continuing to prioritize these evidence-informed approaches is essential for tackling this persistent global health challenge. For more information on the guidelines, refer to the World Health Organization.

Frequently Asked Questions

A child with severe acute malnutrition requires immediate hospitalization if they have a poor appetite (failing the appetite test), severe oedema (+++), or any signs of a medical complication like shock or pneumonia.

Iron supplementation is delayed until the rehabilitation phase because giving it during the initial stabilization phase can worsen existing infections in a compromised system.

F-75 is a lower-protein, lower-energy formula used during the initial stabilization phase. F-100 is a higher-energy and higher-protein formula used in the rehabilitation phase to support rapid catch-up growth.

Yes, CMAM is a highly effective strategy for treating uncomplicated severe acute malnutrition, offering high recovery rates and significantly reducing costs compared to inpatient care for suitable patients.

Dehydration is managed carefully with a specialized, low-sodium rehydration solution called ReSoMal. Rehydration is done slowly to avoid fluid overload, which can be dangerous.

RUTFs are energy-dense, vitamin- and mineral-enriched pastes, like Plumpy'Nut, used to treat uncomplicated severe acute malnutrition in community-based settings.

Refeeding syndrome is a potentially fatal shift in fluid and electrolyte balance that can occur during refeeding after a period of starvation. It is prevented by initiating feeding slowly and cautiously with a low-osmolarity, low-lactose formula like F-75, and closely monitoring the child.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.