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What is zinc Bisglycinate used for? Benefits of this Highly Absorbable Form

4 min read

The human body contains over 300 enzymes that require zinc to function properly, highlighting its essential role in cellular metabolism. Zinc bisglycinate is a highly bioavailable, chelated form of this vital mineral, and is used to support immune function, skin health, and overall wellness due to its superior absorption and tolerability.

Quick Summary

Zinc bisglycinate is a chelated form of the mineral, bound to glycine for superior absorption and better tolerance than other forms. It is used to bolster immune function, promote healthy skin and wound healing, support cellular metabolism, and aid reproductive health.

Key Points

  • Superior Absorption: Zinc bisglycinate's chelated form, bound to glycine, significantly enhances its absorption compared to other zinc supplements.

  • Gentle on the Stomach: The chelated structure makes this form of zinc much easier to digest, reducing the risk of nausea and stomach upset.

  • Boosts Immune System: Supplementation with zinc bisglycinate supports the production of key immune cells and can help reduce the duration of illness.

  • Enhances Skin Health: It is used to regulate sebum production, reduce inflammation, and promote the healing of acne and other skin wounds.

  • Supports Overall Wellness: Zinc bisglycinate aids in healthy hair, skin, and nail maintenance, energy metabolism, and reproductive health.

  • Reduces Deficiency Risk: Its high bioavailability helps effectively prevent and correct zinc deficiency, which can cause symptoms like hair loss and poor wound healing.

  • Avoids Interference: The chelated form protects the zinc ion from interacting negatively with other dietary components, ensuring optimal uptake.

In This Article

Understanding Zinc and its Crucial Role

Zinc is an essential trace mineral found in nearly every cell of the body, playing a critical role in numerous physiological processes. It is required for the catalytic activity of more than 100 enzymes, making it fundamental to cellular function. Some of its key functions include supporting a robust immune system, aiding in protein synthesis and DNA formation, promoting wound healing, and maintaining the senses of taste and smell. Without adequate zinc, the body cannot function optimally, leading to potential deficiencies that can manifest as decreased immunity, slow wound healing, or hair loss. While zinc is found in various foods, certain dietary restrictions or health conditions can impact absorption, making supplementation a necessary consideration for some individuals.

What Makes Zinc Bisglycinate Different?

Unlike some other forms of zinc, such as zinc gluconate or zinc oxide, zinc bisglycinate is a chelated mineral. Chelation is a process where the zinc molecule is bound to two molecules of the amino acid glycine. This unique bonding offers several advantages:

  • Enhanced Bioavailability: The chelation process allows zinc bisglycinate to be absorbed more efficiently by the body compared to standard forms. Studies have shown that bisglycinate can increase absorption significantly over zinc gluconate. This is because it is transported through specialized peptide channels in the digestive tract, which are typically used for protein absorption.
  • Superior Tolerability: The chelated structure makes zinc bisglycinate gentler on the digestive system, reducing the likelihood of gastrointestinal discomfort like nausea or stomach cramps that are sometimes associated with other zinc supplements.
  • Reduced Interference: The chelation protects the zinc from dietary interference, ensuring more efficient uptake into the bloodstream. It is also less likely to compete with the absorption of other minerals.

What is Zinc Bisglycinate Used For? Key Applications

Due to its high bioavailability and gentle nature, zinc bisglycinate is a preferred choice for targeted supplementation. Its uses extend across several health areas:

Enhanced Immune Function

Zinc is a critical component of a healthy immune system, and supplementation is often used to boost immune response. It supports the development and function of immune cells, including T-lymphocytes and natural killer cells, which are crucial for fighting off pathogens. Research suggests that zinc supplementation can help reduce the duration of common cold symptoms when taken within 24 hours of onset.

Promoting Skin Health and Wound Healing

Zinc plays a vital role in maintaining skin integrity and repairing damaged tissue. It is particularly beneficial for managing acne, as it helps regulate sebum production and has anti-inflammatory properties. For wound healing, zinc promotes collagen production and is involved in every stage of the healing process, making bisglycinate an effective supplement for faster recovery, especially for those with low zinc levels.

Supporting Overall Wellness

Beyond immunity and skin, zinc bisglycinate is used for a variety of other health benefits, including:

  • Maintaining healthy bones, hair, and nails.
  • Assisting in energy metabolism and tissue formation.
  • Supporting reproductive health, including testosterone production in men.
  • Protecting cells against oxidative stress due to its antioxidant properties.
  • Contributing to normal cognitive function.

Zinc Supplement Comparison: Bisglycinate vs. Other Forms

When choosing a zinc supplement, understanding the differences between common forms is important. The chelated nature of zinc bisglycinate offers significant advantages over more basic salts.

Feature Zinc Bisglycinate Zinc Gluconate Zinc Oxide
Absorption Rate Very High (Chelated) Moderate (Common) Poor (Inorganic)
GI Tolerability Excellent; Gentle on the stomach Fair; Can cause digestive upset Poor; Highest risk of GI upset
Cost Typically higher than gluconate Standard, widely available Low, often used topically
Best For Enhanced absorption, sensitive stomachs, and targeted benefits General maintenance for individuals with adequate dietary intake Topical applications rather than oral supplementation

How to Take Zinc Bisglycinate

To maximize the benefits and minimize the risk of side effects, it's important to follow proper usage guidelines. The recommended daily intake for adults typically ranges from 15 to 30 milligrams of elemental zinc. Dosage should be determined in consultation with a healthcare professional, especially for those with existing conditions, taking other medications, or with diagnosed deficiencies.

Tips for taking zinc bisglycinate:

  • Take with food: To reduce the risk of nausea or stomach upset, it is best to take your supplement with a meal.
  • Consider timing: If taking other medications or supplements, particularly those containing copper or iron, take your zinc supplement a few hours before or after.
  • Stay within safe limits: The tolerable upper intake level for zinc is 40mg per day for adults. Exceeding this can lead to side effects and potentially interfere with copper absorption.

Conclusion: The Case for Zinc Bisglycinate

For those seeking a zinc supplement with high bioavailability and excellent digestive tolerance, zinc bisglycinate is a standout choice. It addresses a wide range of needs, from bolstering the immune system and fighting infections to promoting clear skin and rapid wound healing. By utilizing its unique chelated structure, this form of zinc maximizes the body's ability to absorb and utilize the mineral effectively. However, as with any supplement, it should be part of a balanced nutritional strategy and used with professional medical guidance, particularly for those with underlying health concerns.

For more in-depth information, a study on the superior bioavailability of zinc bisglycinate can be found on the National Institutes of Health website.

Frequently Asked Questions

Chelated zinc bisglycinate is a form of the mineral zinc that has been bonded with two molecules of the amino acid glycine. This chelation process improves its absorption and makes it gentler on the stomach compared to non-chelated forms.

Research indicates that zinc bisglycinate is more effectively absorbed by the body than zinc gluconate. One study showed a 43.4% increase in absorption when comparing the two forms.

Yes, zinc bisglycinate is used for skin health. Zinc helps regulate the hormones that control sebum secretion, reduces inflammation, and promotes the healing of skin damaged by acne.

Individuals with zinc deficiency, sensitive stomachs, restrictive diets (like vegetarians), or specific health goals such as boosting immunity, improving skin health, or supporting reproductive function can benefit from zinc bisglycinate.

While generally well-tolerated, some individuals may experience mild and temporary digestive side effects like nausea, stomach cramps, or diarrhea, especially with high doses. Taking it with food can help mitigate these effects.

Recommended dosages vary based on individual needs and deficiency levels. For adults, the tolerable upper intake level is 40mg of elemental zinc per day. It is best to consult a healthcare provider to determine the appropriate dosage for you.

You should take zinc supplements a few hours before or after taking other medications or supplements, especially those containing iron or copper, as they can interfere with absorption. Always consult your doctor for personalized advice.

Zinc plays a critical role in all phases of wound healing, from inflammation to tissue repair and collagen production. The highly absorbable nature of zinc bisglycinate ensures the body can effectively utilize the mineral for these processes.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.