Skip to content

When should you not take multivitamins?

4 min read

Over 50,000 instances of vitamin toxicity were reported to US poison control centers in 2021, a stark reminder that while supplements can be beneficial, they are not without risk. Taking a multivitamin can be a crutch for a poor diet, but there are specific scenarios where it is not only unnecessary but potentially harmful.

Quick Summary

Taking multivitamins is generally unnecessary for healthy individuals with a balanced diet and can be dangerous for certain populations. Risks include interactions with medication, potential toxicity from excess fat-soluble vitamins, and specific dangers for smokers and pregnant women.

Key Points

  • Unnecessary for healthy individuals: For most people with a balanced diet, multivitamins are redundant and potentially lead to consuming excessive nutrients.

  • High-risk groups exist: Smokers, pregnant individuals, and people with conditions like liver or kidney disease face specific dangers from multivitamin use.

  • Beware of fat-soluble vitamins: Vitamins A, D, E, and K can accumulate in the body's tissues and cause toxicity if taken in excess from supplements.

  • Can interact with medications: Multivitamins can interfere with prescriptions like blood thinners, antibiotics, and thyroid medication, altering their effectiveness.

  • Stop before surgery: Supplements should be discontinued 1-2 weeks before elective surgery to prevent complications like excessive bleeding.

  • Children are especially vulnerable: Accidental overdose in children, especially with appealing gummy vitamins, is a serious risk, particularly concerning iron.

  • Prioritize whole foods: Obtaining nutrients from a varied diet is the safest and most effective strategy for most people to maintain optimal health.

In This Article

Multivitamins: Not a 'Health Insurance' Policy

For many, a daily multivitamin is seen as a nutritional safety net, filling in gaps from an imperfect diet. However, for most healthy adults, a balanced diet rich in whole foods provides all the necessary nutrients, rendering multivitamins largely redundant. Taking supplements unnecessarily introduces the risk of consuming excessive amounts of certain vitamins and minerals, which can lead to adverse health effects, a condition known as hypervitaminosis. Unlike water-soluble vitamins, which are generally flushed from the body, fat-soluble vitamins (A, D, E, K) are stored in body fat and the liver, making them more likely to accumulate to toxic levels.

High-Risk Groups Who Should Avoid or Be Cautious

Certain populations face a higher risk from unnecessary multivitamin use and should exercise caution or avoid them altogether without medical supervision. These include:

  • Smokers and former smokers: High doses of beta-carotene and vitamin A have been linked to an increased risk of lung cancer in smokers and those with a history of smoking or asbestos exposure. Smokers should specifically avoid multivitamins with high amounts of these nutrients.
  • Pregnant individuals: Excessive preformed vitamin A (found in supplements) during the first trimester can cause birth defects. Prenatal vitamins, designed with safe levels, are appropriate, but standard multivitamins or additional vitamin A supplements should be avoided.
  • Individuals with certain medical conditions: People with liver or kidney disease may have impaired ability to process and eliminate excess vitamins and minerals, increasing the risk of toxicity. Those with hemochromatosis, an iron storage disorder, should also avoid iron-containing multivitamins.
  • Children: Children are at a higher risk of vitamin toxicity due to their smaller body size and lower tolerance for high doses. Multivitamins, especially appealing gummy vitamins, can lead to accidental overdose, and excessive iron is a leading cause of poisoning in young children.

Potential for Dangerous Drug Interactions

Nutrients in multivitamins can interfere with the effectiveness or absorption of various prescription medications. This can have serious consequences, making it critical to discuss all supplements with a healthcare provider before use.

  • Blood thinners (e.g., Warfarin): The high vitamin K content in some multivitamins can counteract blood-thinning medications, increasing the risk of blood clots.
  • Tetracycline antibiotics: Minerals like calcium, magnesium, and iron can reduce the absorption and effectiveness of tetracycline antibiotics. It is recommended to separate the dose times.
  • Thyroid medications: Iron and calcium can interfere with the absorption of thyroid medications, such as levothyroxine.
  • Cancer treatments: High doses of certain antioxidant vitamins may interact with radiation therapy, potentially reducing its effectiveness.

The Risks of Over-Supplementation

It is entirely possible to get too much of a good thing. Over-supplementation, especially when combining fortified foods with multivitamins or taking multiple supplements, is a significant risk factor for toxicity.

  • Excessive intake of fat-soluble vitamins like A can lead to symptoms such as nausea, dizziness, liver damage, and bone pain.
  • Too much vitamin D can cause hypercalcemia, leading to symptoms like nausea, vomiting, weakness, and potential kidney damage.
  • High doses of certain B vitamins, while water-soluble, are not without risk. For instance, high-dose B6 can cause nerve damage, and excessive niacin can cause liver toxicity.

Stopping Multivitamins Before Surgery

For those preparing for elective surgery, taking multivitamins should generally be stopped in the weeks leading up to the procedure. Supplements can cause complications related to bleeding and drug interactions with anesthesia and other medications.

  • Many healthcare providers, including those at Stanford Medicine, recommend stopping all vitamins, herbs, and diet supplements 7 to 14 days before surgery to reduce the risk of excessive bleeding.
  • The risk of bleeding is a primary concern, as supplements like vitamin E and fish oil can thin the blood.
  • It is vital to inform your surgeon and medical team of all supplements you are taking during pre-operative consultations.
Situation Multivitamin Recommendation Reasoning Potential Risk
Healthy Adult (Balanced Diet) Avoid/Unnecessary Nutrient needs are met through diet; excess intake is possible. Toxicity from fat-soluble vitamins.
Smoker/Former Smoker Avoid high Beta-carotene/Vitamin A Linked to increased risk of lung cancer. Cancer risk.
Pregnant (1st Trimester) Avoid standard multivitamins Excess Vitamin A can cause birth defects. Use a prescribed prenatal. Birth defects.
Taking Blood Thinners Avoid with Vitamin K Vitamin K can counteract medication effects. Increased blood clot risk.
Preparing for Surgery Stop 1-2 weeks prior Many supplements increase bleeding risk and interact with anesthesia. Bleeding complications.
Liver/Kidney Disease Avoid without medical supervision Impaired organ function affects metabolism and excretion. Increased risk of toxicity.
Infants/Children Avoid or give with caution Higher risk of accidental overdose and toxicity due to smaller body size. Iron poisoning, vitamin toxicity.

What to do instead of taking a multivitamin

Rather than relying on a pill, prioritize a balanced diet. Focus on consuming a variety of whole foods to ensure you get a broad spectrum of nutrients naturally. If you suspect a deficiency, a blood test can confirm it, allowing for targeted supplementation of a specific nutrient under a doctor’s care, rather than a broad-spectrum, high-dose multivitamin. Always consult a healthcare professional before starting or stopping any supplement, especially if you have underlying health conditions or are on other medications.

Conclusion

While a multivitamin might seem like a simple solution for nutritional worries, it is not a one-size-fits-all remedy. For most healthy individuals, a balanced diet is sufficient and safer. There are specific circumstances—such as smoking, pregnancy, certain medical conditions, and impending surgery—where taking a multivitamin can pose real risks, from dangerous nutrient overdoses to problematic drug interactions. The best approach is always to seek personalized medical advice to determine your specific nutritional needs and avoid unnecessary supplementation. The guidance from a healthcare professional is your best defense against the potential harm of multivitamin misuse.

Frequently Asked Questions

It is highly unlikely to reach toxic levels of vitamins from consuming food alone. Toxicity from vitamins almost always occurs due to high-dose supplementation.

Initial symptoms can be mild and non-specific, including nausea, vomiting, fatigue, headache, or stomach cramps. For fat-soluble vitamins, signs can include blurred vision or skin issues.

Studies have shown that smokers who take high doses of beta-carotene or vitamin A may have an increased risk of lung cancer. It is crucial for smokers and former smokers to avoid these supplements.

Certain ingredients in multivitamins, such as vitamin E, can have blood-thinning effects, which increases the risk of bleeding during and after surgery. It is standard practice to stop all supplements before elective surgery.

Fat-soluble vitamins (A, D, E, K) are stored in the body's fatty tissues and liver, making them easier to build up to toxic levels. Water-soluble vitamins (B and C) are typically excreted in urine, making toxicity less likely but not impossible at extremely high doses.

If you suspect an overdose, especially in a child, contact a local poison control center immediately by calling 1-800-222-1222 in the United States. Provide the product name, strength, time, and amount swallowed.

Read labels carefully to check dosages and serving sizes, and be aware of fortified foods that contribute to your total intake. Avoid taking multiple supplements with overlapping nutrients, and consult a healthcare provider for personalized advice.

References

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
  7. 7
  8. 8
  9. 9
  10. 10

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.