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Which Disease Is Called Marasmus?

4 min read

According to the World Health Organization (WHO), over 50 million children under five are wasted, a condition that can include the severe malnutrition known as marasmus. Marasmus is the formal name for a disease caused by severe and prolonged undernourishment, specifically a deficiency of all macronutrients, which leads to extreme wasting.

Quick Summary

Marasmus is a severe form of protein-energy malnutrition, primarily caused by an overall deficiency of calories and nutrients, resulting in extreme wasting of fat and muscle tissue.

Key Points

  • Protein-Energy Malnutrition: Marasmus is a severe form of protein-energy undernutrition, a deficiency of all major macronutrients.

  • Cause is Starvation: The primary cause is inadequate caloric and nutrient intake, often due to food scarcity, poverty, or chronic illness.

  • Characterized by Wasting: A key sign is the visible wasting of fat and muscle, giving the affected individual an emaciated, 'skin and bones' appearance.

  • Affects Growth and Development: In children, marasmus can cause stunted growth, developmental delays, and a severely compromised immune system.

  • Differs from Kwashiorkor: Unlike kwashiorkor, which features edema (swelling), marasmus is characterized by severe wasting without fluid retention.

  • Treatment Requires Caution: Medical treatment involves a phased approach to nutritional rehabilitation, beginning slowly to prevent dangerous 'refeeding syndrome'.

  • Prevention Focuses on Access: Preventing marasmus relies on improving food security, sanitation, healthcare access, and nutritional education in at-risk communities.

In This Article

What is Marasmus?

Marasmus is a severe form of malnutrition, technically classified as a type of Severe Acute Malnutrition (SAM). The name 'marasmus' comes from the Greek word 'marainein,' which means 'to waste away'. It is characterized by a critical deficiency in all macronutrients—carbohydrates, proteins, and fats—leading to a severe lack of energy. The body's response to this severe deprivation is to consume its own fat and muscle tissues for energy, resulting in a dangerously low body mass and an emaciated, wasted appearance. While it can affect anyone experiencing starvation, it most commonly impacts infants and young children in developing countries where poverty and food scarcity are widespread.

The Body's Reaction to Starvation

When a person suffers from marasmus, their body enters a state of physiological adaptation to survive prolonged hunger. This process includes:

  • Consuming its own tissues: The body first uses up all its fat stores, followed by muscle mass, to generate energy.
  • Slowing metabolic rate: To conserve energy, the body reduces its overall metabolic rate and shuts down certain functions.
  • Compromising the immune system: The immune system is weakened, leaving the person highly vulnerable to infections and diseases.
  • Affecting organ systems: Vital functions are slowed, which can lead to low heart rate, low blood pressure, and low body temperature.

Symptoms and Complications of Marasmus

The signs and symptoms of marasmus are often visibly distressing due to the extreme wasting of body tissues.

Prominent Signs of Marasmus

  • Severe Weight Loss: The most evident sign is a significant loss of weight, leaving the person severely underweight.
  • Wasting of Fat and Muscle: This is the defining feature, leading to a 'skin and bones' appearance where joints and ribs are prominent.
  • Emaciated Appearance: The face may appear shrunken, and in children, can take on an 'old man's face' or 'wizened' look due to the loss of subcutaneous fat.
  • Dry, Wrinkled Skin: The skin often becomes loose and wrinkled, hanging in folds due to the loss of underlying fat.
  • Stunted Growth: In children, prolonged malnutrition severely impacts growth and development, leading to stunting.
  • Apathy and Irritability: The person, especially a child, may appear lethargic, weak, and uninterested in their surroundings, often accompanied by irritability.

Serious Complications

Left untreated, marasmus can lead to a host of serious and potentially fatal complications. These include:

  • Frequent infections due to a severely compromised immune system.
  • Dehydration and electrolyte imbalances.
  • Organ dysfunction, such as heart failure.
  • Delayed intellectual and physical development.
  • Long-term issues such as glucose intolerance and a higher risk of non-communicable diseases.

Distinguishing Marasmus from Kwashiorkor

Marasmus is often discussed alongside another form of severe malnutrition, kwashiorkor. While both result from undernutrition, they have distinct clinical features.

Feature Marasmus Kwashiorkor
Primary Deficiency Severe deficiency of all macronutrients (protein, carbs, fat). Primarily a deficiency of protein.
Physical Appearance Extreme wasting of fat and muscle; emaciated, 'skin and bones' look. Edema (swelling) of the hands, feet, face, and often a distended belly.
Subcutaneous Fat Markedly absent; consumed by the body for energy. Subcutaneous fat may be present, masking the true extent of malnutrition.
Appetite Can be ravenous, though some may have anorexia. Usually poor, with loss of appetite.
Skin & Hair Dry, thin, and wrinkled skin; brittle hair. Skin changes like peeling, lesions, and altered pigmentation; hair changes color and texture.
Age of Onset Most common in infants under 1 year. Typically affects children over 18 months.

Treatment and Prevention of Marasmus

Treating marasmus requires careful medical supervision, especially to avoid refeeding syndrome, a life-threatening complication that can occur when the severely malnourished body is fed too aggressively.

Treatment Stages

  1. Stabilization: The initial stage focuses on correcting dehydration, electrolyte imbalances, and infections. Specialized rehydration solutions may be used.
  2. Nutritional Rehabilitation: In this stage, feeding begins slowly with special liquid formulas that are gradually increased in calories, protein, and fat. Nasogastric tube feeding is often used initially.
  3. Catch-Up Growth and Follow-up: As the person stabilizes, the focus shifts to ensuring they receive enough nutrition for catch-up growth and recovery. Ongoing monitoring and dietary education are crucial to prevent a relapse.

Prevention is Key

Preventing marasmus is a global health priority, with interventions targeting at-risk populations and communities.

  • Ensure Food Security: Addressing the root causes of poverty and food scarcity through sustainable development and aid programs is paramount.
  • Promote Education: Educating parents and caregivers on proper nutrition, breastfeeding practices, and hygiene is vital, particularly in resource-limited settings.
  • Access to Healthcare: Providing access to primary care, vaccinations, and treatment for infectious diseases can prevent the illnesses that often exacerbate malnutrition.
  • Support for Vulnerable Groups: In developed countries, addressing malnutrition in at-risk groups like the elderly or those with eating disorders is crucial.

Conclusion

Marasmus is not a separate, named disease but rather the term for a severe and acute form of malnutrition. It results from a profound deficiency of all caloric intake, leading to the body's self-consumption of fat and muscle tissues. Characterized by severe wasting, stunted growth, and a compromised immune system, it is a life-threatening condition that most often affects infants and children in impoverished regions. However, with careful, supervised nutritional rehabilitation, many individuals can make a full recovery, highlighting the importance of prevention through addressing global food security and improving nutritional education. For further information on the global impact and statistics, consult resources from organizations like UNICEF or WHO.

Frequently Asked Questions

The main difference lies in their primary deficiency and appearance. Marasmus results from a deficiency of all macronutrients (calories, protein, fat) and causes severe wasting, while kwashiorkor is primarily a protein deficiency and causes edema, or fluid-induced swelling.

Marasmus most commonly affects infants and young children under five, especially those in developing countries with high rates of poverty and food scarcity. The elderly and individuals with certain chronic illnesses or eating disorders are also at risk.

Visible signs include severe weight loss, an emaciated 'skin and bones' appearance, dry and wrinkled skin, and a shrunken face. Children may also exhibit stunted growth, lethargy, and irritability.

Doctors diagnose marasmus through a physical examination, looking for visible signs of wasting. They also take anthropometric measurements, such as weight-for-height, and may use blood tests to assess nutritional status and rule out infections.

A major risk is refeeding syndrome, a potentially fatal complication caused by sudden shifts in fluids and electrolytes when a severely undernourished person is fed too rapidly. Treatment must therefore be gradual and medically supervised.

Yes, with proper and timely medical treatment and nutritional rehabilitation, many children can recover fully. However, severe or prolonged cases can lead to long-term health issues, including permanent cognitive or developmental delays.

Long-term effects can include stunted physical growth, chronic health problems, impaired neurodevelopment leading to cognitive deficits, and an increased risk of conditions like glucose intolerance and type 2 diabetes.

Prevention involves ensuring an adequate, balanced diet for at-risk populations. This includes measures like improving food security, promoting nutritional education, and providing access to clean water and healthcare to prevent infectious diseases.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.