Skip to content

Which Essential Amino Acids Are Likely to Be Lacking in Corn?

5 min read

While corn is a staple food worldwide, studies have shown that its protein quality is limited due to low levels of specific essential amino acids. This article explores which essential amino acids are likely to be lacking in corn and how this impacts overall nutritional value.

Quick Summary

Corn protein is deficient in the essential amino acids lysine and tryptophan because its primary protein, zein, lacks these crucial nutrients. It is an incomplete protein and should be paired with other foods.

Key Points

  • Lysine and Tryptophan Are Limiting: Normal corn is primarily deficient in these two essential amino acids.

  • Zein Protein Is the Cause: The low protein quality is due to the dominance of zein proteins in the endosperm, which lack these amino acids.

  • Combine with Legumes: Pair corn with legumes like beans or peas to form a complete protein source, as they provide the missing amino acids.

  • Biofortified Corn Exists: "Quality Protein Maize" (QPM) is a biofortified variety bred to have higher levels of lysine and tryptophan.

  • Impacts Monogastric Animals: The deficiency is particularly relevant for monogastric animals (including humans) who cannot synthesize these amino acids.

  • Processing Affects Quality: Refined corn products, which remove the nutrient-rich germ, have even lower lysine content.

  • Historical Context: Traditional diets that combine corn and beans have historically compensated for this nutritional gap.

In This Article

The Missing Links in Corn's Protein Profile

Corn, or maize, is one of the world's most vital cereal crops, serving as a primary energy source for both humans and livestock globally. However, from a nutritional standpoint, its protein quality is considered low when compared to sources like animal products or soybeans. This is because corn is an "incomplete protein," meaning it lacks sufficient amounts of certain essential amino acids that the human body cannot produce on its own. The most significant limiting essential amino acids in corn are lysine and tryptophan.

The Reason for the Deficiency: Zein Proteins

To understand why corn is deficient in specific amino acids, one must look at the structure of its protein. The protein content in a corn kernel is not evenly distributed. The endosperm, which makes up a large portion of the kernel's dry weight, contains a high concentration of storage proteins called zeins. Zein proteins are naturally rich in amino acids like leucine, alanine, and proline, but are severely deficient in lysine and tryptophan. In contrast, the corn germ contains protein of higher quality, but since the endosperm is the dominant component, especially in refined corn products, the overall amino acid profile is skewed. This dominance of low-quality zein protein is the primary reason for the nutritional imbalance.

Limiting Amino Acids in Corn

Based on decades of nutritional research, a clear hierarchy of corn's limiting amino acids has been established, particularly for monogastric animals like humans and pigs.

  • Lysine: This is consistently the most limiting amino acid in corn and other cereal grains. Studies have shown that adding lysine to a corn-based diet significantly improves protein utilization. Refined corn products, where the germ is removed, have an even lower lysine content than whole corn.
  • Tryptophan: Also a major limiting amino acid, tryptophan deficiency often occurs alongside lysine deficiency. In fact, some studies indicate that lysine and tryptophan can be considered co-limiting.
  • Threonine and Isoleucine: While less severely limited than lysine and tryptophan, these amino acids may also be deficient, depending on the specific corn variety and dietary context.

Strategies for Addressing the Deficiency

Because corn is a staple in many diets, it is crucial to address these protein limitations to prevent malnutrition. Fortunately, there are several effective strategies.

  • Complementary Proteins: The most traditional and widespread solution is pairing corn with a food rich in the missing amino acids. Legumes, such as beans, peas, and lentils, are excellent complementary proteins. This pairing is famously seen in many Latin American and Native American cuisines, such as corn tortillas and beans.
  • Adding Protein Sources: In addition to legumes, other protein sources can be added to a corn-based diet to create a complete amino acid profile. Soy, milk, and animal proteins are effective supplements.
  • Quality Protein Maize (QPM): Modern agricultural science has developed genetically modified corn varieties, known as Quality Protein Maize, specifically to address these nutritional gaps. By modifying the genetics, scientists have managed to reduce zein content and increase lysine and tryptophan levels, significantly improving corn's biological value. QPM was developed to help combat malnutrition in maize-dependent communities.

Comparison of Corn vs. Complete Protein Sources

To illustrate the nutritional differences, consider the limiting amino acids compared to a complete protein source like soy.

Feature Normal Corn Soybeans Rationale for Difference
Primary Limiting Amino Acid Lysine and Tryptophan Methionine (less limited) Corn's zein proteins lack these two key amino acids.
Biological Value (Monogastric) Low, often 40-57% High, often considered the best plant protein Corn protein is poorly utilized due to the amino acid imbalance.
Nutritional Quality Incomplete Protein Complete Protein (relative) Soy provides a more balanced amino acid profile, complementing corn's deficiencies.
Primary Protein Type Zeins (in endosperm) Albumins and Globulins Protein composition varies significantly between plants, leading to different amino acid profiles.

Conclusion: A Balanced Approach Is Key

While conventional corn is an excellent source of energy and other nutrients, its incomplete protein profile is a notable nutritional limitation due to its low content of lysine and tryptophan. This is a critical factor for individuals and animals relying on corn as a dietary staple. The deficiency can be easily managed by pairing corn with complementary protein sources like legumes or through the use of modern biofortified varieties like Quality Protein Maize. Understanding these limitations and implementing appropriate dietary strategies ensures a more complete and balanced nutritional intake. For more information on the genetic advancements in maize, see the research published in the National Institutes of Health(https://pmc.ncbi.nlm.nih.gov/articles/PMC7688887/).

Frequently Asked Questions

What essential amino acids are likely to be lacking in corn?

Corn is most commonly deficient in the essential amino acids lysine and tryptophan. Depending on the specific variety and other dietary factors, it may also be low in isoleucine and threonine.

Why is corn an incomplete protein?

Corn is an incomplete protein because its primary storage protein, known as zein, is low in certain essential amino acids, particularly lysine and tryptophan. Essential amino acids must be obtained from the diet, and corn does not provide them in adequate balance.

How can I make a complete protein with corn?

You can make a complete protein with corn by combining it with a complementary protein source. The most common and effective combination is pairing corn with legumes, such as beans, peas, or lentils, which provide the missing lysine and tryptophan.

What is Quality Protein Maize (QPM)?

Quality Protein Maize (QPM) is a genetically biofortified variety of corn developed to have naturally higher levels of the essential amino acids lysine and tryptophan than traditional corn. This makes it a more nutritionally complete food source.

Is the amino acid deficiency in corn a problem for animals?

Yes, the deficiency in lysine and tryptophan is a significant factor in animal nutrition, especially for monogastric animals like pigs and poultry. Animal feed manufacturers must supplement corn with other protein sources to ensure proper growth and health.

Do you have to eat complementary proteins at the same meal?

No, it is not necessary to consume complementary proteins at the same meal to get the nutritional benefits. The body can draw from a pool of amino acids available in the bloodstream for several hours, so eating complementary foods throughout the day is sufficient.

Why are traditional corn and bean dishes so important nutritionally?

Traditional dishes like corn tortillas and beans are nutritionally important because they strategically combine two incomplete proteins to create a complete protein source. This practice has historically ensured that populations relying on these foods receive all necessary essential amino acids.

Frequently Asked Questions

Corn is considered an incomplete protein because its primary storage protein, zein, is low in certain essential amino acids, primarily lysine and tryptophan. Essential amino acids cannot be produced by the body and must be obtained from food.

Corn is most notably deficient in lysine and tryptophan. In some varieties or specific dietary contexts, isoleucine and threonine may also be limiting factors.

Zein proteins are the major storage proteins in corn's endosperm but are notably deficient in lysine and tryptophan, which lowers the overall nutritional value of corn protein.

You can make a complete protein by combining corn with a complementary protein source, such as legumes like beans, peas, or lentils, which are rich in the amino acids that corn lacks.

Quality Protein Maize (QPM) is a genetically biofortified variety of corn with increased levels of lysine and tryptophan to improve its nutritional value. It was developed to provide a more nutritionally complete staple crop.

No, the body maintains a circulating pool of amino acids for several hours after eating. Therefore, consuming complementary protein sources like corn and beans throughout the day is sufficient to meet your essential amino acid needs.

The deficiency is a concern for monogastric animals, including humans, who cannot synthesize these essential amino acids. Ruminants, such as cattle, have different digestive systems that allow them to process protein differently.

References

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.