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Which of the Following Diseases is Caused by Malnutrition?: A Detailed Guide

5 min read

According to the World Health Organization, undernutrition is linked to nearly half of all deaths in children under five. It is a critical risk factor, making children and adults vulnerable to several life-threatening conditions, so understanding which of the following diseases is caused by malnutrition is vital for prevention and health.

Quick Summary

Several diseases, including kwashiorkor, marasmus, and various vitamin deficiencies, are directly caused by malnutrition. These conditions result from insufficient intake of essential nutrients and can lead to severe complications if untreated.

Key Points

  • Kwashiorkor: Caused by severe protein deficiency, this condition is characterized by edema (swelling) and is often seen in weaning children.

  • Marasmus: A severe lack of overall calories, protein, and fat leads to a visibly emaciated and wasted appearance.

  • Scurvy: Results from a prolonged lack of vitamin C, leading to symptoms like bleeding gums and poor wound healing.

  • Rickets: A deficiency of vitamin D and calcium causes weakened bones and skeletal deformities, particularly in children.

  • Pellagra: A niacin (vitamin B3) deficiency, especially common with corn-based diets, presents with diarrhea, dermatitis, and dementia.

  • Beriberi: A thiamine (vitamin B1) deficiency affecting the cardiovascular and nervous systems, often from diets heavy in polished rice.

  • Iron-Deficiency Anemia: A lack of iron impairs red blood cell production, causing fatigue and pale skin.

  • Goiter: The most common cause of this thyroid enlargement worldwide is iodine deficiency.

In This Article

Understanding Malnutrition and Its Consequences

Malnutrition refers to deficiencies, excesses, or imbalances in a person's intake of energy and/or nutrients. It is a broad term encompassing both undernutrition (stunting, wasting, underweight, and micronutrient deficiencies) and overweight/obesity. Inadequate intake of specific vitamins and minerals, often called micronutrients, can severely impair the body's ability to produce enzymes, hormones, and other substances essential for proper growth and development. The resulting conditions can range from relatively mild to life-threatening, affecting all ages but particularly impacting children and pregnant women.

Kwashiorkor: Severe Protein Deficiency

Kwashiorkor is a severe form of protein-energy malnutrition (PEM) resulting from a diet that is very low in protein but high in carbohydrates. The name comes from a Ga language phrase meaning "the sickness the baby gets when the new baby comes," as it often occurs in older infants who are abruptly weaned off protein-rich breast milk when a new sibling is born. A key feature of kwashiorkor is edema (swelling), particularly in the ankles, feet, face, and belly, which can mask the true extent of emaciation.

Common Symptoms of Kwashiorkor:

  • Bloated, distended abdomen due to fluid retention (edema).
  • Dry, brittle hair that may change color.
  • Dermatitis, leading to dry, peeling skin and scaly patches.
  • Enlarged, fatty liver.
  • Muscle wasting, which may be hidden by the edema.
  • Lethargy, irritability, and apathy.

Marasmus: General Calorie and Nutrient Deficiency

Unlike kwashiorkor, marasmus is a deficiency of all macronutrients—protein, carbohydrates, and fats—leading to a severe lack of overall calories. It is characterized by visible wasting of fat and muscle tissue, giving the individual a shrunken, emaciated appearance. The body consumes its own tissues to survive, leading to a significantly low body mass index (BMI). Marasmus can occur in anyone with severe undernutrition but is most common in infants and young children.

Common Symptoms of Marasmus:

  • Severe wasting and emaciation, with visible ribs and a prominent skeleton.
  • The appearance of loose, hanging skin folds.
  • Stunted growth in children.
  • An aged or wizened facial expression.
  • Lethargy, apathy, and weakness.
  • Low body temperature and a slow heart rate.

Comparing Key Malnutrition Diseases

Feature Kwashiorkor Marasmus Scurvy Rickets
Primary Deficiency Severe protein deficiency with relatively adequate carbohydrates. Overall calorie, protein, and fat deficiency. Vitamin C (ascorbic acid) deficiency. Vitamin D and/or calcium deficiency.
Appearance Edema (swelling) of the limbs and face, often with a bloated belly. Emaciated, wasted appearance with loss of muscle and fat. Characterized by bleeding gums, skin hemorrhages, and corkscrew hairs. Softening and weakening of bones, leading to bowed legs and skeletal deformities.
Key Symptoms Edema, fatty liver, dry hair, dermatitis, apathy. Visible wasting, stunted growth, severe weight loss, lethargy. Weakness, joint pain, anemia, poor wound healing. Bone pain, muscle weakness, delayed growth, dental problems.
Population at Risk Weaning children, especially in regions with high-carb, low-protein diets. Infants and young children in impoverished areas; elderly and those with chronic diseases. Individuals with very poor diets lacking fresh fruits and vegetables. Exclusively breastfed infants, darker-skinned children, those with limited sun exposure.

Other Malnutrition-Related Conditions

  • Beriberi: A disease caused by a severe deficiency of thiamine (vitamin B1). It primarily affects the cardiovascular and nervous systems, leading to symptoms like shortness of breath, rapid heart rate (wet beriberi), muscle weakness, and mental confusion (dry beriberi). It is most commonly associated with diets relying heavily on refined white rice and can also affect people with chronic alcoholism.
  • Pellagra: Results from a severe deficiency of niacin (vitamin B3), often affecting populations whose diets consist primarily of corn, as the niacin in corn is poorly absorbed. It is classically associated with the "4 Ds": diarrhea, dermatitis, dementia, and death. The characteristic dermatitis appears on sun-exposed areas.
  • Scurvy: This condition is caused by a severe, prolonged lack of vitamin C, essential for collagen synthesis. Symptoms include general weakness, fatigue, bleeding gums, skin hemorrhages, and impaired wound healing. Scurvy was historically a problem for sailors on long voyages but is now rare in developed nations.
  • Rickets: Occurs due to a vitamin D deficiency, which leads to poor absorption of calcium and phosphorus. This causes the bones to become soft and weak, resulting in skeletal deformities such as bowed legs, bone pain, and delayed growth. The adult equivalent is osteomalacia.
  • Iron-Deficiency Anemia: A lack of sufficient iron prevents the body from producing enough hemoglobin, a protein in red blood cells that carries oxygen. It is the most common type of anemia worldwide and can be caused by low dietary intake, malabsorption, or blood loss. Symptoms include fatigue, pale skin, shortness of breath, and dizziness.
  • Goiter: An irregular growth or enlargement of the thyroid gland, which is most commonly caused by iodine deficiency globally. In iodine-sufficient regions, it can be caused by other thyroid disorders.
  • Night Blindness (Nyctalopia): This symptom, making it hard to see in dim light, can be caused by a vitamin A deficiency. The body needs vitamin A to produce rhodopsin, a protein in the retina that helps with vision in low light. Severe vitamin A deficiency can lead to irreversible blindness.

Prevention and Treatment

Preventing diseases caused by malnutrition relies heavily on a balanced and nutrient-rich diet. Public health measures, such as food fortification (e.g., iodized salt, niacin-enriched cereals) and promoting breastfeeding, have significantly reduced the prevalence of some of these conditions in developed countries. Addressing underlying poverty and food insecurity is crucial for prevention in vulnerable populations globally.

Treatment varies depending on the specific deficiency. For most conditions, supplementation with the missing nutrient is the primary course of action. In severe cases, particularly with kwashiorkor and marasmus, treatment is a carefully managed, multi-stage process to prevent complications like refeeding syndrome. In addition, addressing any underlying infections or other health issues is essential for full recovery. Education on proper nutrition and food preparation is also vital, especially for caregivers.

Conclusion

Malnutrition is not a single condition but a broad state of poor nutrition that manifests as a range of distinct and serious diseases. As this article has highlighted, conditions such as kwashiorkor, marasmus, and deficiencies like pellagra and scurvy are all direct consequences of an inadequate diet. The specific disease depends on the missing nutrient, whether it's protein, a vital vitamin, or overall calories. Recognizing the symptoms and understanding the root causes is the first step toward effective prevention and treatment. A balanced diet and targeted interventions are key to combating these avoidable diseases worldwide. Further information can be found on the World Health Organization's website.

World Health Organization - Malnutrition

Frequently Asked Questions

Marasmus results from a severe deficiency of total calories, protein, and fat, leading to a visibly emaciated appearance. Kwashiorkor is primarily a protein deficiency, even if calorie intake is adequate, and is characterized by edema (swelling) that can hide muscle wasting.

Yes, many vitamin deficiencies are directly caused by malnutrition, particularly micronutrient undernutrition. Examples include scurvy (vitamin C), pellagra (vitamin B3), beriberi (vitamin B1), rickets (vitamin D), and night blindness (vitamin A).

Primary pellagra is caused by a diet lacking sufficient niacin (vitamin B3) and the amino acid tryptophan, often seen in populations where corn is a staple food and not properly processed. Secondary pellagra can be caused by conditions that prevent nutrient absorption, such as alcoholism.

The classic signs of scurvy, caused by severe vitamin C deficiency, include swollen and bleeding gums, easy bruising, skin hemorrhages (red or blue spots), and impaired wound healing.

Rickets is most commonly caused by a vitamin D deficiency, which prevents proper calcium absorption. However, a severe lack of calcium or phosphorus in the diet can also lead to rickets, particularly in children.

Iron-deficiency anemia is typically treated with oral iron supplements, along with dietary adjustments to increase iron-rich foods. In severe cases, intravenous iron or a blood transfusion may be necessary.

The most common cause of goiter globally is a lack of iodine in the diet. In regions where iodized salt is widely used, other thyroid disorders are more likely to be the cause.

Yes, malnutrition can lead to severe psychological symptoms. Conditions like pellagra can cause dementia and confusion, while severe undernutrition can cause apathy, lethargy, and behavioral problems.

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.