Scurvy in a modern context
Scurvy, a disease resulting from severe vitamin C deficiency, was historically associated with sailors on long voyages who lacked fresh produce. However, modern scurvy is not a relic of the past. Although rates are low in the general population, specific groups in the US remain highly vulnerable due to various dietary, medical, and socioeconomic factors. The body’s vitamin C stores become depleted over several months of inadequate intake, leading to symptoms like fatigue, bleeding gums, easy bruising, and poor wound healing. Early recognition is crucial for effective treatment with vitamin C supplementation.
High-risk populations for scurvy in the US
Children with restrictive diets and neurodevelopmental conditions
Childhood scurvy cases have seen a notable increase, often linked to extreme food selectivity. This is particularly common in children with autism spectrum disorder (ASD), where sensory sensitivities can lead to very narrow diets, often excluding fruits and vegetables. Other neurodevelopmental conditions like cerebral palsy can also cause feeding difficulties, putting these children at risk.
- Selective Eating: Children with ASD or Avoidant/Restrictive Food Intake Disorder (ARFID) may consume a diet of only a few preferred items, such as processed foods, eliminating vitamin C-rich options.
- Developmental Delays: Conditions affecting motor skills can impact a child's ability to eat a wide variety of foods, or may be associated with other feeding issues.
- Inadequate Weaning: Infants exclusively fed cow's milk or boiled milk are at risk, as pasteurization destroys vitamin C and these products are not nutritionally complete for infants. Most commercial formulas are fortified, but improper feeding practices can still lead to issues.
The elderly and socially isolated individuals
Older adults face several challenges that increase their risk of poor nutrition and subsequent vitamin C deficiency. Social isolation, reduced appetite, and limited financial resources can all contribute to diets lacking in fresh fruits and vegetables. This pattern is sometimes referred to as the "tea and toast" diet.
Individuals with alcohol use disorder
Chronic alcohol abuse is a significant risk factor for scurvy. This is due to a combination of inadequate dietary intake, impaired nutrient absorption in the gut, and increased metabolic stress. Malnourished alcoholics may present with various signs of nutrient deficiencies, and scurvy can easily be overlooked.
Patients with malabsorption and chronic diseases
Several medical conditions and procedures can interfere with the body's ability to absorb or utilize vitamin C, or increase its requirements.
- Bariatric Surgery: Weight-loss surgeries like gastric bypass or sleeve gastrectomy can significantly alter the gut's anatomy, leading to impaired vitamin C absorption and a higher risk of deficiency.
- Dialysis Patients: Individuals with end-stage renal disease on chronic hemodialysis or peritoneal dialysis are at heightened risk because vitamin C is a water-soluble vitamin that is filtered out during the dialysis process.
- Inflammatory Bowel Disease: Conditions like Crohn's disease and celiac disease can cause poor nutrient absorption due to inflammation in the small intestine, where vitamin C is typically absorbed.
- Iron Overload Disorders: Certain genetic blood disorders like thalassemia can lead to iron overload, which can increase vitamin C consumption.
Other vulnerable groups
Beyond these primary categories, other groups face elevated risk:
- Smokers: Smoking increases the body's oxidative stress, which accelerates the breakdown of vitamin C. As a result, smokers require a higher daily intake of vitamin C than non-smokers to maintain adequate levels.
- Individuals with Mental Illness: Psychiatric conditions such as schizophrenia, depression, or anorexia nervosa can be associated with extremely poor dietary habits and disinterest in self-care, increasing malnutrition risk.
- Low Socioeconomic Status: Limited access to or affordability of fresh fruits and vegetables is a major driver of malnutrition, impacting economically disadvantaged individuals and families.
- Homeless Individuals: This population often has unreliable access to fresh food and adequate nutrition, placing them at significant risk.
Comparison of Historical vs. Modern Scurvy Risk Factors
| Feature | Historical Scurvy (e.g., sailors) | Modern Scurvy (US) |
|---|---|---|
| Primary Cause | Prolonged lack of access to fresh produce during long sea voyages. | Chronic inadequate intake due to a range of dietary, medical, and social issues. |
| Dietary Pattern | Monotonous, non-perishable diet of staples like dried meat and hardtack. | Restrictive diets, high intake of processed foods, low fruit/vegetable consumption. |
| Affected Population | Adult male sailors. | Children, the elderly, individuals with certain chronic illnesses, and those with substance abuse issues. |
| Contributing Factors | Limited knowledge of nutrition, environmental constraints. | Underlying health conditions (ASD, dialysis), socioeconomic barriers, behavioral issues. |
| Prevalence | High mortality rates during voyages. | Rare but with pockets of rising incidence in specific at-risk groups. |
Conclusion: Vigilance and targeted support are key
While scurvy is not a widespread public health crisis in the United States, its persistence among certain vulnerable groups highlights ongoing nutritional disparities. The increasing incidence in the pediatric population, particularly among those with conditions like autism, underscores the need for greater awareness among healthcare providers and caregivers. For adults, factors like alcohol use, bariatric surgery, and dialysis require diligent monitoring and appropriate vitamin C supplementation. By recognizing the specific risk factors that can lead to severe vitamin C deficiency, targeted nutritional education and intervention can effectively prevent and treat this otherwise easily manageable condition.
For more detailed nutritional information, consult the NIH's Vitamin C Fact Sheet.