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Who Should Not Take Adaptogens? Understanding the Risks and Contraindications

5 min read

According to a study involving adverse event reports, adaptogens were implicated in 9% of side effects when combined with antidepressants. While adaptogens are widely praised for their stress-reducing benefits, certain populations must exercise extreme caution or avoid them altogether. Knowing who should not take adaptogens is essential for safe and effective use.

Quick Summary

Despite their popularity, adaptogens carry risks for specific groups. Individuals who are pregnant or breastfeeding, have autoimmune conditions, or take certain medications for conditions like diabetes or high blood pressure should consult a healthcare professional. Not all adaptogenic herbs are suitable for everyone.

Key Points

  • Pregnancy and Breastfeeding: Adaptogens are contraindicated for pregnant and breastfeeding individuals due to hormonal risks and insufficient safety data.

  • Autoimmune Conditions: Those with autoimmune diseases should be cautious as adaptogens can modulate the immune system, potentially worsening symptoms.

  • Medication Interactions: Adaptogens can interact with numerous drugs, including blood thinners, immunosuppressants, diabetes, and blood pressure medications.

  • Pre-Surgical Patients: Individuals undergoing surgery should stop taking adaptogens beforehand due to effects on blood clotting and interaction with medications.

  • Specific Herbs to Note: Adaptogens like ginseng, ashwagandha, and rhodiola have specific contraindications that require careful consideration.

In This Article

Who Needs to Avoid Adaptogens? A Closer Look at Contraindications

Adaptogens are a group of non-toxic plants, such as ashwagandha, ginseng, and rhodiola, marketed to help the body resist stressors of all kinds. However, their powerful effects on the body's neuroendocrine and immune systems mean they are not universally safe. Certain populations are at a higher risk of adverse reactions and should approach these supplements with caution, and often avoid them completely.

Pregnancy and Breastfeeding

One of the most significant warnings for adaptogen use is for pregnant and breastfeeding women. The hormonal fluctuations during pregnancy are complex and tightly regulated, and adaptogens can interfere with this delicate balance. Some adaptogens, like ashwagandha, are considered abortifacient and could potentially cause miscarriage. For breastfeeding mothers, there is insufficient data to determine if the compounds pass into breast milk and affect the infant. It is best for pregnant and nursing mothers to err on the side of caution and avoid adaptogens.

Autoimmune Disorders

Individuals with autoimmune diseases such as rheumatoid arthritis, lupus, or multiple sclerosis need to be extremely careful with adaptogens. Many adaptogenic herbs are known for their immune-modulating effects, which can either stimulate or suppress the immune system. In someone with an overactive immune system, certain adaptogens could theoretically exacerbate disease activity. For example, rhodiola and ashwagandha, known immune modulators, could potentially worsen symptoms.

Individuals on Specific Medications

The potential for drug-herb interactions is a critical consideration for anyone taking prescription medication. The following are some key drug classes that can interact with adaptogens:

  • Blood Thinners (Anticoagulants): Certain adaptogens, like ginseng and cordyceps, can interfere with blood clotting, increasing the risk of bleeding when taken with medications such as warfarin.
  • Immunosuppressants: Since some adaptogens enhance immune function, they can counteract the effects of medications designed to suppress the immune system, which is crucial for organ transplant recipients or those with severe autoimmune conditions.
  • Diabetes Medications: Adaptogens like ginseng and reishi can lower blood sugar levels. Combining them with diabetes drugs can lead to hypoglycemia (dangerously low blood sugar).
  • Blood Pressure Medications: Some adaptogens, including rhodiola and ginseng, can affect blood pressure, leading to dangerously low levels if taken with antihypertensive drugs.
  • Antidepressants: A retrospective review found that combining adaptogens like ashwagandha and eleuthero with antidepressants can lead to adverse events due to additive effects or interactions with metabolic pathways.

Before and After Surgery

Because adaptogens can affect blood clotting, blood pressure, and interact with anesthetics and other perioperative medications, they should be discontinued well before any surgical procedure. It is vital to inform your surgeon about all supplements you are taking to ensure a safe procedure and recovery.

Other Health Conditions and Considerations

Beyond specific diseases and medications, other groups should proceed with caution:

  • Children and Adolescents: Adaptogens are not recommended for individuals under 18 due to insufficient research on their long-term effects on developing systems.
  • Thyroid Disorders: Adaptogens like ashwagandha can stimulate thyroid hormone activity. People with hyperthyroidism should avoid it, and those on thyroid medication should consult a doctor before use.
  • Hormone-Sensitive Cancers: Some adaptogens may have hormonal effects. Individuals with hormone-sensitive conditions, such as prostate cancer, should avoid them.

Adaptogen Risk Comparison Table

Health Condition/Group Primary Risk(s) Specific Adaptogens to Watch Recommended Action
Pregnancy/Breastfeeding Hormonal interference, potential abortifacient effects, unknown safety for infant Ashwagandha, Schisandra, Ginseng Avoid completely
Autoimmune Disease Immune system stimulation, exacerbation of symptoms Ashwagandha, Rhodiola, Reishi Consult doctor; proceed with caution
Blood Thinners (e.g., Warfarin) Increased bleeding risk due to anti-clotting effects Ginseng, Cordyceps Avoid completely
Diabetes Medication Risk of hypoglycemia (low blood sugar) Ginseng, Reishi, Rhodiola Consult doctor; monitor blood sugar closely
Blood Pressure Medication Risk of dangerously low blood pressure Ginseng, Rhodiola, Reishi Consult doctor; monitor blood pressure
Immunosuppressants Reduced effectiveness of medication Ginseng, Eleuthero Avoid completely
Antidepressants Adverse effects, including increased sedative or stimulatory effects Ashwagandha, Rhodiola, Eleuthero Consult doctor; risk of severe interactions
Before/After Surgery Interference with blood clotting, blood pressure, and anesthetics Ginseng, Cordyceps, Ashwagandha Discontinue use well in advance
Children under 18 Insufficient safety data for developing bodies All Adaptogens Avoid completely

Conclusion: Prioritize Safety Above All Else

While adaptogens offer a range of potential health benefits, it is crucial to recognize that they are not harmless. For individuals with specific medical conditions, those on certain medications, and during critical life stages like pregnancy, the risks often outweigh the potential benefits. The term “natural” does not equate to “safe for all”. Always consult with a healthcare professional before adding any new supplement to your regimen, especially if you fall into one of the at-risk categories. A thorough discussion with a doctor can prevent potential complications and ensure your health is the top priority. For reliable medical information, consult a resource like MedlinePlus.

Keypoints

  • Pregnancy and Breastfeeding: Adaptogens are contraindicated for pregnant and breastfeeding individuals due to hormonal risks and insufficient safety data.
  • Autoimmune Conditions: Those with autoimmune diseases should be cautious as adaptogens can modulate the immune system, potentially worsening symptoms.
  • Medication Interactions: Adaptogens can interact with numerous drugs, including blood thinners, immunosuppressants, diabetes, and blood pressure medications.
  • Pre-Surgical Patients: Individuals undergoing surgery should stop taking adaptogens beforehand due to effects on blood clotting and interaction with medications.
  • Specific Herbs to Note: Adaptogens like ginseng, ashwagandha, and rhodiola have specific contraindications that require careful consideration.

FAQs

Q: Is it safe for me to take ashwagandha if I have a thyroid condition? A: No, ashwagandha can stimulate thyroid hormone production and should be avoided by people with hyperthyroidism. If you are on thyroid medication, do not combine it with ashwagandha without a doctor's explicit approval.

Q: Can I combine adaptogens with my antidepressant medication? A: No, it is strongly advised against. Combining adaptogens like ashwagandha or eleuthero with antidepressants can lead to severe side effects and metabolic interactions that affect the medication's efficacy.

Q: Are adaptogens safe for children or adolescents? A: No, the use of adaptogens is not recommended for anyone under the age of 18 due to the lack of sufficient safety data regarding their effects on developing bodies.

Q: Can a person with diabetes safely take adaptogens? A: Individuals with diabetes should be cautious and consult their doctor. Certain adaptogens like ginseng can significantly lower blood sugar, which could lead to hypoglycemia when combined with diabetes medications.

Q: What are the risks of taking adaptogens with blood thinners? A: Taking adaptogens with blood-thinning medications like warfarin increases the risk of bleeding. Herbs such as ginseng and cordyceps can interfere with blood clotting and should be avoided.

Q: Should I stop taking adaptogens before surgery? A: Yes. Because adaptogens can affect blood clotting and blood pressure, it is crucial to inform your doctor and stop taking them well in advance of any scheduled surgery.

Q: Do adaptogens have any side effects for generally healthy people? A: Even in healthy individuals, adaptogens can cause side effects, though typically mild. Common side effects can include digestive upset, headaches, or allergic reactions. It's always best to start with a small dose and monitor your body's response.

Frequently Asked Questions

No, ashwagandha can stimulate thyroid hormone production and should be avoided by people with hyperthyroidism. If you are on thyroid medication, do not combine it with ashwagandha without a doctor's explicit approval.

No, it is strongly advised against. Combining adaptogens like ashwagandha or eleuthero with antidepressants can lead to severe side effects and metabolic interactions that affect the medication's efficacy.

No, the use of adaptogens is not recommended for anyone under the age of 18 due to the lack of sufficient safety data regarding their effects on developing bodies.

Individuals with diabetes should be cautious and consult their doctor. Certain adaptogens like ginseng can significantly lower blood sugar, which could lead to hypoglycemia when combined with diabetes medications.

Taking adaptogens with blood-thinning medications like warfarin increases the risk of bleeding. Herbs such as ginseng and cordyceps can interfere with blood clotting and should be avoided.

Yes. Because adaptogens can affect blood clotting and blood pressure, it is crucial to inform your doctor and stop taking them well in advance of any scheduled surgery.

Even in healthy individuals, adaptogens can cause side effects, though typically mild. Common side effects can include digestive upset, headaches, or allergic reactions. It's always best to start with a small dose and monitor your body's response.

No, different adaptogens have unique properties and distinct risk profiles. For example, ashwagandha is associated with thyroid issues and sedative effects, while ginseng has cardiovascular and stimulant effects. It is important to research the specific adaptogen you are considering.

Yes, as with any plant-based substance, adaptogens can cause allergic reactions in some people. Symptoms can include rash, swelling, or breathing issues. Those with a known allergy to other nightshade plants, for example, should be careful with ashwagandha.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.