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Who should not take cod liver oil? Important contraindications explained

5 min read

While cod liver oil has been a popular dietary supplement for decades, offering benefits from omega-3 fatty acids and vitamins A and D, its high concentration of fat-soluble vitamins and potential blood-thinning effects make it unsuitable for everyone. It is critical to understand the contraindications to avoid potential health risks.

Quick Summary

Cod liver oil is not safe for everyone, especially those on blood thinners, pregnant or breastfeeding women, and individuals with specific health conditions or upcoming surgeries, primarily due to its high vitamin A content and natural blood-thinning properties.

Key Points

  • Pregnant and breastfeeding individuals: Should avoid cod liver oil due to high vitamin A levels, which can cause birth defects.

  • Individuals on blood thinners: The omega-3s in cod liver oil can increase the risk of bleeding in those taking anticoagulant medications.

  • Pre-surgery patients: It is standard practice to stop taking cod liver oil at least two weeks before a scheduled operation to minimize bleeding risks.

  • High-risk of hypervitaminosis: People with elevated vitamin A or D levels should avoid cod liver oil to prevent vitamin toxicity.

  • Bleeding disorders: Individuals with hemophilia or other bleeding disorders should not take cod liver oil due to its blood-thinning properties.

  • Chronic health conditions: People with kidney disease, high blood calcium, or diabetes should consult a doctor before use, as cod liver oil can impact their conditions.

In This Article

What is Cod Liver Oil?

Cod liver oil is a type of fish oil extracted specifically from the livers of cod fish. It is distinct from regular fish oil because of its nutritional profile, which includes significant amounts of naturally occurring vitamins A and D, in addition to omega-3 fatty acids (EPA and DHA). While these nutrients can be beneficial for heart health, bone density, and inflammation, their high concentration, especially vitamin A, can pose serious health risks for certain individuals.

Who Should Not Take Cod Liver Oil?

Several groups of people should avoid or exercise extreme caution when considering cod liver oil supplementation. Always consult a healthcare professional before starting any new supplement regimen.

1. Pregnant or Breastfeeding Individuals

One of the most critical warnings regarding cod liver oil is for pregnant women or those planning a pregnancy. The concern lies with the high concentration of preformed vitamin A (retinol). Excessive intake of vitamin A can be teratogenic, meaning it can cause birth defects, and in severe cases, miscarriage. The risk comes from the liver's ability to store this fat-soluble vitamin, leading to a build-up over time that can cross the placenta and affect fetal development. During pregnancy, most healthcare providers recommend getting omega-3s from purified fish oil (derived from fish flesh, not liver) or algae oil, which contain little to no vitamin A.

  • Recommended Alternatives during Pregnancy:
    • Purified Fish Oil: Provides beneficial omega-3s without the high vitamin A levels.
    • Algae Oil: A vegan source of DHA and EPA, completely free of vitamin A.

2. People on Blood-Thinning Medication

Cod liver oil has natural blood-thinning properties due to its omega-3 fatty acid content. For individuals taking anticoagulant or antiplatelet drugs, such as warfarin, clopidogrel, or even daily aspirin, this can be extremely dangerous. The combined effect could increase the risk of bruising, internal bleeding, or prolonged bleeding from minor cuts. Medical supervision is necessary if an individual on blood thinners insists on taking a fish oil supplement.

3. Individuals with Bleeding Disorders

Similar to those on blood-thinning medication, individuals with existing bleeding disorders like hemophilia should avoid cod liver oil. The potential for increased bleeding is a significant risk that could lead to severe complications. The supplement's impact on platelet aggregation and clotting time can worsen the condition.

4. Patients with Upcoming Surgery

Due to its effect on blood clotting, doctors generally advise patients to stop taking cod liver oil and other omega-3 supplements at least two weeks before any planned surgery, including dental work. This precaution helps to minimize the risk of excessive bleeding during and after the procedure. Recent research has nuanced this view, suggesting moderate doses might not pose a high risk, but standard practice remains cautious.

5. People with Hypervitaminosis A or D

Since vitamins A and D are fat-soluble, they are stored in the body's liver and fat tissues. Taking excessive doses of cod liver oil, especially in combination with other vitamin A or D supplements, can lead to hypervitaminosis, or vitamin toxicity.

  • Hypervitaminosis A symptoms: Severe headaches, blurred vision, dizziness, nausea, and potentially liver damage.
  • Hypervitaminosis D symptoms: Can cause abnormally high levels of calcium in the blood, leading to nausea, vomiting, weakness, and potential kidney problems.

6. Individuals with Specific Medical Conditions

Certain pre-existing health issues warrant careful consideration before taking cod liver oil.

  • Kidney Disease: Individuals with compromised kidney function should consult a doctor, as excessive vitamin A can strain the kidneys.
  • High Blood Calcium/Phosphate: Those with already high levels of calcium or phosphate in their blood (hypercalcemia/hyperphosphatemia) should avoid cod liver oil due to its high vitamin D content, which aids calcium absorption.
  • Diabetes: Cod liver oil can affect blood sugar levels, sometimes causing a drop that could interfere with antidiabetes medications. Diabetics should closely monitor their blood sugar if they choose to supplement with cod liver oil.

Cod Liver Oil vs. Purified Fish Oil: A Comparison

To highlight the key differences, especially for vulnerable populations, consider this comparison table:

Feature Cod Liver Oil Purified Fish Oil Consideration for Special Groups
Source Liver of cod fish Flesh of oily fish (e.g., mackerel, sardines) Cod Liver Oil: Higher risk due to liver sourcing of fat-soluble vitamins. Purified Fish Oil: Safer for pregnant women and those monitoring vitamin A intake.
Vitamin A High amounts (as retinol) Very low to none Cod Liver Oil: Risk of hypervitaminosis A, particularly during pregnancy. Purified Fish Oil: Does not carry a risk of vitamin A toxicity.
Vitamin D Significant amounts Varies; some may have added vitamin D Both sources can contribute to total vitamin D intake, but cod liver oil's higher concentration should be monitored.
Omega-3s (EPA/DHA) Rich source Rich source Both provide beneficial omega-3s, but the delivery mechanism and overall nutrient profile differ.
Toxin Risk Potential for higher heavy metal or contaminant levels due to liver processing, though purified versions exist. Generally lower risk, as toxins accumulate more in fat than flesh, and purification is standard. Always choose a reputable brand with third-party testing for purity.

General Dosage and Safety Guidelines

For those who are not in a high-risk group, following general guidelines can help ensure safe supplementation. A common dose for adults is typically 1 to 2 teaspoons, or up to 1 tablespoon daily, but exceeding recommended amounts can increase vitamin A intake beyond safe limits. It is also advisable to take cod liver oil with a meal to minimize potential side effects like heartburn or stomach upset.

Before taking cod liver oil, and especially if you are taking any other medications or have a chronic health condition, it is vital to consult a healthcare provider. They can assess your individual needs and risks, and determine if cod liver oil is appropriate for you. For example, studies on the interaction between cod liver oil and statins for high cholesterol are still ongoing, highlighting the need for professional guidance.

Conclusion

While cod liver oil is celebrated for its rich nutritional profile, it is not a universally suitable supplement. Individuals who are pregnant or breastfeeding, on blood-thinning medication, have a bleeding disorder, or are preparing for surgery must avoid it or do so only under strict medical supervision. Furthermore, those at risk of hypervitaminosis A or D, or managing conditions like kidney disease or diabetes, should proceed with caution. Opting for purified fish oil or algae oil may be safer alternatives for many. The key to safe supplementation is prioritizing personalized medical advice over generalized wellness claims. For further information on general dietary advice, resources like the NHS website provide helpful guidance on vitamins and supplements during pregnancy.

Frequently Asked Questions

No, it is generally recommended to avoid cod liver oil during pregnancy and breastfeeding. It contains high levels of vitamin A (retinol), which can be harmful to a developing fetus.

Yes, cod liver oil can interact with and potentiate the effects of blood-thinning medications. Its omega-3 fatty acids can slow blood clotting, increasing the risk of bleeding.

Cod liver oil is extracted from the liver of cod and is rich in vitamins A and D, in addition to omega-3s. Regular fish oil is made from the flesh of oily fish and typically contains only omega-3s, with minimal to no vitamins A and D.

Yes, you should stop taking cod liver oil at least two weeks before any scheduled surgery. This is to reduce the risk of excessive bleeding during and after the procedure.

Yes, vitamins A and D are fat-soluble and can accumulate in the body. Taking excessive doses of cod liver oil, especially combined with other supplements, can lead to toxicity, known as hypervitaminosis.

For those concerned about high vitamin A, purified fish oil (from fish flesh) or algae oil are safe alternatives. These supplements provide omega-3s without the risk of vitamin A toxicity.

Diabetics should be cautious and monitor their blood sugar levels closely if taking cod liver oil. It may cause blood sugar to drop, potentially interacting with diabetes medication.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.