Who Shouldn't Take Ryze Mushroom Coffee?

January 13, 2026 •

4 min read

Functional mushrooms, like those in Ryze mushroom coffee, are not suitable for everyone, particularly individuals with specific pre-existing health conditions or those who are pregnant. While often marketed for their adaptogenic properties, it's crucial to understand the contraindications and potential side effects before incorporating this supplement into your daily regimen.

Quick Summary

This guide details the specific individuals and conditions for which Ryze mushroom coffee may be unsafe, covering potential drug interactions, sensitivities, and risk factors related to its mushroom content and caffeine.

Key Points

Pre-existing Conditions: Individuals with kidney problems (especially a history of kidney stones), diabetes, autoimmune disorders, or bleeding issues should avoid Ryze mushroom coffee due to potential risks and interactions.
Medication Interactions: People on blood thinners, immunosuppressants, or medications for blood pressure and diabetes should consult a doctor, as mushrooms can interfere with these prescriptions.
Pregnancy and Nursing: Avoid Ryze mushroom coffee if you are pregnant or breastfeeding, as there is insufficient research on its safety during these periods.
Allergies and Sensitivities: Those with allergies to fungi or sensitive digestive systems may experience adverse reactions like rashes, bloating, or stomach upset.
Adjustment Period: Expect potential temporary side effects like headaches or digestive changes when first switching from high-caffeine coffee due to the lower caffeine content and introduction of new compounds.
Lack of Regulation: As a dietary supplement, Ryze is not FDA regulated, so caution is advised regarding its potency, safety, and dosage.

Understanding the Risks of Ryze Mushroom Coffee

While mushroom coffee blends like Ryze are celebrated for their potential health benefits, such as reduced caffeine jitters and immune support, they are not universally safe. The blend of functional mushrooms, including Reishi, Cordyceps, and Chaga, can present risks for certain populations. The primary concerns revolve around existing health issues, medication interactions, and potential allergies. It is essential to be informed about these risks to make a responsible health decision.

Individuals with Pre-existing Health Conditions

Certain health conditions make consuming Ryze mushroom coffee a potential hazard. The adaptogenic properties and specific compounds in the mushrooms can interfere with the body's natural processes. Consulting a doctor before use is highly recommended for anyone with underlying health concerns.

Kidney Problems: Mushrooms, especially Chaga, contain high levels of oxalates. These compounds can contribute to the formation of kidney stones in susceptible individuals. For those with a history of kidney disease or stones, mushroom coffee is best avoided.
Autoimmune Disorders: As some medicinal mushrooms are known to have immunomodulatory effects, they could potentially stimulate the immune system. Individuals with autoimmune disorders like rheumatoid arthritis, lupus, or multiple sclerosis should proceed with caution and consult their physician, as this stimulation could theoretically worsen their condition.
Bleeding Disorders: High doses of certain mushrooms, particularly Reishi, may slow blood clotting. This poses a significant risk for those with bleeding disorders or those taking blood-thinning medication.
Diabetes: The mushrooms in Ryze coffee, such as Reishi and Cordyceps, have been shown to lower blood sugar levels. While this could be beneficial for some, it can be dangerous for people with diabetes, as it might lead to dangerously low blood sugar levels, especially when combined with antidiabetes medications.

People on Specific Medications

Drug interactions are a serious consideration for those interested in Ryze mushroom coffee. The active compounds within medicinal mushrooms can alter how certain prescription drugs function in the body.

Blood Thinners (Anticoagulants): As noted, Reishi and Cordyceps can slow blood clotting. If you are on medications like warfarin or heparin, consuming mushroom coffee could increase the risk of bruising and bleeding.
Immunosuppressants: Because mushrooms can affect the immune system, they might interfere with immunosuppressant drugs taken by organ transplant recipients or those with severe autoimmune conditions.
Blood Pressure Medications: Reishi and Chaga mushrooms may lower blood pressure, which could cause an excessive drop in pressure when combined with antihypertensive drugs.

Pregnant or Nursing Individuals

There is a significant lack of research regarding the safety of medicinal mushrooms for pregnant or breastfeeding women. Given the uncertainty and the potential risks, it is advised to avoid Ryze mushroom coffee during this time to ensure the safety of both mother and baby.

Individuals with Allergies and Gastrointestinal Sensitivity

Even for healthy individuals, adverse reactions are possible. Allergies to fungi are a clear contraindication. The adaptogenic nature and high fiber content can also trigger digestive discomfort.

Fungi Allergies: Anyone with a known allergy or intolerance to mushrooms should not consume mushroom coffee. Allergic reactions can include skin rashes, dizziness, or digestive upset.
Sensitive Digestive Systems: Some users report mild bloating, gas, or other gastrointestinal issues, especially during an initial adjustment period. People with conditions like Irritable Bowel Syndrome (IBS) may be particularly sensitive.

Ryze Mushroom Coffee vs. Regular Coffee: Key Differences


Feature	Ryze Mushroom Coffee	Regular Coffee	Potential Issue	Who Should Avoid
Caffeine Content	Approximately 48mg per serving (about half of regular coffee).	~95mg per serving.	Caffeine Withdrawal: Users reducing high caffeine intake may experience temporary headaches or fatigue.	Those sensitive to caffeine fluctuations.
Mushroom Content	Contains extracts from Lion's Mane, Cordyceps, Reishi, Shiitake, Turkey Tail, and King Trumpet.	Contains only roasted coffee beans.	Drug Interactions: Mushrooms can interfere with blood thinners, immunosuppressants, and diabetes meds.	People on certain prescription medications.
Oxalate Content	Some mushrooms, especially Chaga, are high in oxalates.	Naturally low in oxalates.	Kidney Stone Risk: High oxalate intake can increase risk of kidney stones.	Individuals with a history of kidney stones or kidney problems.
Digestive Impact	Mushroom polysaccharides may cause bloating and gas in some sensitive individuals.	Can cause stomach irritation, especially on an empty stomach.	Gut Sensitivity: Potential for increased gastrointestinal distress.	People with sensitive digestive systems or IBS.
Regulation	FDA does not regulate dietary supplements like this, so dosage and safety are less controlled.	Highly regulated as a food product.	Lack of Oversight: Concerns over potency and quality control.	Consumers who require stringent product regulation.

The Importance of Doctor Consultation

Given the potential for interaction with both pre-existing conditions and medications, a conversation with a healthcare provider is the most critical step before starting Ryze mushroom coffee. They can evaluate your personal health history, current prescriptions, and potential risk factors. It is a prudent measure to ensure safety and avoid complications, especially since some of the effects can be severe, such as excessive bleeding or dangerously low blood sugar.

Conclusion

While Ryze mushroom coffee presents itself as a wellness-focused alternative to traditional coffee, it is not without risks for certain individuals. Anyone with kidney problems, autoimmune disorders, bleeding disorders, or diabetes should exercise extreme caution. Furthermore, pregnant or nursing women, individuals with fungi allergies, and those on specific medications like blood thinners or immunosuppressants are also advised to avoid it or seek professional medical advice. The lack of rigorous FDA oversight for dietary supplements means that consumers must take responsibility for understanding the potential downsides. Ultimately, a thoughtful and informed approach, guided by a healthcare provider, is the best way to determine if Ryze mushroom coffee is right for you.

Disclaimer: This article is for informational purposes only and does not constitute medical advice. Consult a healthcare professional for personalized guidance regarding supplements.

Frequently Asked Questions

No, you should avoid Ryze mushroom coffee if you have a history of kidney stones or kidney problems. Mushrooms, particularly Chaga, contain high levels of oxalates, which can increase the risk of forming kidney stones.

Yes, it can. Medicinal mushrooms can interact with several medications, including blood thinners (anticoagulants), immunosuppressants, and drugs for managing blood pressure and diabetes. It is crucial to speak with your doctor before consuming it if you are on any medication.

The safety of Ryze mushroom coffee for pregnant and nursing women is not well-researched, so it is recommended to avoid it during these times as a precaution.

Common side effects can include digestive issues like bloating, gas, or an upset stomach, especially during an adjustment period. Allergic reactions are also possible, causing symptoms like a rash, dizziness, or a dry mouth.

Yes, if you have kidney problems. Chaga mushrooms are high in oxalates, which can be problematic for individuals susceptible to kidney stones.

If you are switching from a high-caffeine regimen, you might experience temporary caffeine withdrawal symptoms, such as headaches or brain fog, due to Ryze's lower caffeine content.

While generally safe for most healthy people, daily consumption should be cleared by a doctor if you have any pre-existing health conditions, especially relating to kidney or digestive issues.