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Anti-Nutrients and More: What is something that can decrease a nutrient's bioavailability?

4 min read

A review published in Food Production, Processing and Nutrition found that phytic acid, a common anti-nutrient, can significantly hinder mineral absorption by forming indigestible complexes. This highlights that something that can decrease a nutrient's bioavailability often includes natural compounds present in our food sources.

Quick Summary

Several factors, including natural anti-nutrients in plants, food preparation methods, and specific nutrient interactions, can reduce how effectively the body absorbs and uses nutrients.

Key Points

  • Anti-nutrients: Compounds like phytates, oxalates, and tannins naturally present in plant foods can bind with minerals, making them unavailable for absorption.

  • Nutrient Interactions: Certain nutrients, such as calcium and non-heme iron, can compete for the same absorption pathways, thereby decreasing the bioavailability of one or both.

  • Cooking and Preparation: Methods like boiling can cause water-soluble vitamins to leach out, while processes like soaking, sprouting, and fermentation can reduce anti-nutrient levels.

  • Individual Health: Factors such as age, gut health, and certain malabsorption disorders like Crohn's disease or celiac disease can significantly impact nutrient uptake.

  • Dietary Balance: The overall composition of a meal, including its fat and fiber content, influences bioavailability. High-fat meals can enhance the absorption of fat-soluble vitamins.

  • Food Form: The chemical form of a nutrient matters, such as the difference in bioavailability between heme iron (from meat) and non-heme iron (from plants).

In This Article

Bioavailability is a crucial concept in nutrition, referring to the proportion of a nutrient from food that is absorbed and utilized by the body. While the quantity of a nutrient is important, its bioavailability determines the actual nutritional benefit. Numerous factors can act as inhibitors, reducing the availability of nutrients. Understanding these elements can help individuals optimize their dietary intake and make more informed food preparation choices.

Natural Anti-Nutrients in Plant Foods

Many plant-based foods contain compounds known as anti-nutrients, which can interfere with nutrient absorption. These substances are naturally occurring and, in some cases, serve a protective role for the plant itself.

Phytates (Phytic Acid)

Phytates, or phytic acid, are widely found in whole grains, seeds, nuts, and legumes. They are a primary anti-nutrient that binds to minerals like iron, zinc, calcium, and magnesium, forming an insoluble complex that cannot be absorbed by the intestines. This is particularly relevant for individuals on vegetarian or vegan diets who rely heavily on these plant sources for minerals. The good news is that soaking, sprouting, and fermentation can help break down phytates and improve mineral absorption.

Oxalates (Oxalic Acid)

Oxalates are compounds found in many plant foods, with high concentrations in certain leafy greens (e.g., spinach, rhubarb), nuts, and beans. Similar to phytates, oxalates can bind with calcium and iron, forming insoluble crystals that the body cannot absorb. This interaction is the main reason why the calcium in spinach, for example, is not highly bioavailable. Boiling these vegetables can significantly reduce their oxalate content, as the compounds can leach into the cooking water.

Tannins

Tannins are polyphenolic compounds responsible for the astringent, bitter taste in foods like tea, coffee, and certain legumes. They can inhibit the absorption of non-heme iron (the type found in plants) by forming complexes with it in the digestive tract. To minimize this effect, it's recommended to avoid drinking tea or coffee with iron-rich meals.

Lectins and Saponins

Lectins, found in legumes and whole grains, are proteins that can bind to the cells lining the digestive tract, potentially interfering with nutrient absorption. Saponins, present in legumes and some grains, can also impair nutrient absorption and reduce the digestibility of proteins. However, adequate cooking and soaking typically destroy or deactivate these anti-nutrients.

Nutrient-Nutrient Interactions and Food Combinations

Beyond anti-nutrients, the combination of different nutrients in a single meal can either enhance or inhibit absorption. Some nutrients compete for the same absorption pathways in the intestines, which can decrease the bioavailability of one or both.

  • Calcium vs. Iron: Calcium can interfere with the absorption of non-heme iron. It's best to take iron supplements at a different time than calcium supplements or high-calcium meals.
  • Zinc vs. Iron: These two minerals can compete for absorption, especially when consumed in large supplemental doses.
  • Vitamin C and Iron: In a beneficial interaction, Vitamin C significantly enhances the absorption of non-heme iron. Pairing iron-rich plant foods with a source of Vitamin C (e.g., adding bell peppers to a lentil dish) is a recommended strategy.

The Role of Food Processing and Cooking Methods

How food is prepared can drastically change a nutrient's bioavailability. Some methods help, while others hinder.

Inhibitory Cooking Techniques

  • Boiling: As mentioned with oxalates, boiling can cause water-soluble nutrients like Vitamin C and B vitamins to leach out into the cooking water, which is often discarded.
  • Milling: The process of milling grains removes the nutrient-rich bran layer, which contains many of the vitamins, minerals, and fibers, thus decreasing the overall nutritional value.

Enhancing Cooking Techniques

  • Steaming and Microwaving: These methods use less water and shorter cooking times, which better preserve heat-sensitive nutrients compared to boiling.
  • Cooking Fat-Soluble Nutrients: Cooking certain foods, like tomatoes, can increase the bioavailability of specific nutrients. The lycopene in cooked tomatoes is more readily absorbed than from raw tomatoes. Additionally, consuming fat-soluble vitamins (A, D, E, K) with dietary fats enhances their absorption.
  • Fermentation and Soaking: These traditional methods are effective at reducing anti-nutrient levels in grains and legumes, thereby increasing mineral and protein bioavailability.

Comparing Key Nutrient Inhibitors

Inhibitor (Type) Found In Reduces Bioavailability Of Mitigation Strategy
Phytates (Anti-nutrient) Whole grains, legumes, seeds, nuts Iron, zinc, calcium, magnesium Soaking, sprouting, fermentation, cooking
Oxalates (Anti-nutrient) Spinach, rhubarb, tea, beets Calcium, iron Boiling (discard water), pairing with calcium source
Tannins (Anti-nutrient) Tea, coffee, grapes, cocoa Non-heme iron Consume separately from iron-rich meals
Dietary Fiber (Dietary Factor) Whole grains, fruits, vegetables Some minerals, fats Balanced diet, processing methods like milling
Calcium (Nutrient Interaction) Dairy, supplements Non-heme iron Take supplements and iron-rich foods at different times

Host and Health Factors Affecting Bioavailability

The individual's internal health can play a significant role in how well they absorb nutrients. Factors such as age, genetics, and the presence of digestive disorders can all influence bioavailability.

  • Age: As people age, natural physiological changes, such as a decrease in stomach acid, can impair the absorption of certain nutrients, most notably Vitamin B12.
  • Health Status: Conditions like Crohn's disease, celiac disease, or chronic pancreatitis can cause malabsorption due to inflammation or damage to the small intestine.
  • Nutritional Status: The body's current nutrient stores can affect absorption. For example, individuals with low iron stores will absorb more dietary iron.
  • Gut Health: The balance of the intestinal microbiome can influence nutrient absorption and overall digestive function.

For more in-depth information, you can consult resources like the NIH's Principles of Nutritional Assessment.

Conclusion

In summary, several factors can decrease a nutrient's bioavailability, including the presence of anti-nutrients in food, nutrient-nutrient interactions, certain preparation methods, and individual health conditions. While anti-nutrients are a natural component of many healthy plant foods, their impact can often be minimized through simple culinary techniques like soaking, sprouting, and cooking. By understanding these inhibiting factors and employing effective strategies, we can improve our body's ability to absorb and utilize the vital nutrients from our diet, ensuring a more complete nutritional profile.

Frequently Asked Questions

The primary factors are anti-nutrients like phytates, oxalates, and tannins, along with nutrient-nutrient interactions and certain food preparation methods.

Phytates, found in grains and legumes, bind to minerals such as iron, zinc, and calcium in the digestive tract, forming an insoluble compound that prevents their absorption by the body.

Yes, cooking methods can significantly impact bioavailability. For instance, boiling vegetables can cause water-soluble vitamins to leach into the water, while steaming or microwaving can preserve them better.

Yes, chronic health conditions and disorders like celiac disease, Crohn's disease, and pancreatic insufficiency can lead to malabsorption, reducing the body's ability to absorb nutrients.

You can reduce the effects of anti-nutrients by using food preparation techniques like soaking, sprouting, or fermenting grains and legumes. Cooking also helps deactivate many anti-nutrients.

Heme iron, from animal sources, is more readily absorbed by the body. Non-heme iron, from plant sources, is less bioavailable and is more susceptible to the inhibitory effects of anti-nutrients.

High intake of certain types of dietary fiber, particularly viscous soluble fiber, can interfere with the absorption of some minerals and fats. However, it's not a major concern in a balanced diet.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.