Skip to content

Are there any dangers of creatine? Separating myth from fact

4 min read

Despite decades of research supporting its safety, the question 'are there any dangers of creatine?' continues to be a common concern. This popular supplement is often surrounded by myths regarding kidney damage and dehydration, but when used appropriately, it is considered safe for most healthy individuals.

Quick Summary

Creatine is a safe and effective supplement for most healthy adults, with potential mild side effects like digestive upset at high doses. Misconceptions about kidney damage are debunked by science, but individuals with pre-existing conditions should seek medical advice. Staying hydrated and following recommended dosages minimizes risks.

Key Points

  • Safety for healthy adults: Numerous studies confirm creatine is safe for healthy individuals when used at recommended doses, with long-term use not harming kidney function.

  • Kidney myth debunked: The fear of kidney damage is a myth; increased creatinine levels during supplementation are a normal metabolic effect, not a sign of kidney failure.

  • Mild side effects: Potential minor side effects include temporary water weight gain and possible gastrointestinal distress, especially at high doses.

  • Minimize discomfort: High-dose loading phases can cause stomach issues; opting for a consistent, lower daily dose or splitting doses can mitigate this.

  • Consult a doctor: Individuals with pre-existing conditions like kidney disease, diabetes, or bipolar disorder should consult a healthcare provider before starting creatine.

  • Prioritize hydration: Staying well-hydrated is key, as creatine increases water retention in muscles. This helps prevent discomfort and supports optimal function.

In This Article

Creatine is a naturally occurring compound derived from amino acids that helps muscles produce energy during high-intensity exercise. It has become one of the most widely researched and used dietary supplements in the world of sports and fitness. Yet, persistent myths and anecdotal claims continue to raise questions about its safety.

Debunking the biggest creatine myths

Many of the common fears associated with creatine are not supported by science. Here is a closer look at some of the most prominent misconceptions.

The kidney damage myth

This is perhaps the most widespread and persistent myth surrounding creatine use. The concern stems from the fact that creatine is broken down into creatinine, a waste product filtered by the kidneys. When supplementing with creatine, blood creatinine levels naturally increase. An elevated reading on a lab test can be mistakenly interpreted as a sign of kidney problems.

What the science says: Numerous long-term studies, including one lasting up to 5 years, have consistently shown that creatine supplementation does not harm kidney function in healthy individuals. However, those with pre-existing kidney disease should avoid it and always consult a doctor.

The dehydration and cramping myth

Another common concern is that creatine causes dehydration and muscle cramps by drawing water into the muscles. Anecdotal reports are often used to fuel this fear, but clinical evidence suggests the opposite.

What the science says: Research by the International Society of Sports Nutrition (ISSN) and others indicates that creatine may have a hyper-hydrating effect, increasing total body water. Studies on athletes have shown that those who supplement with creatine experienced fewer instances of cramping and heat-related illness. Adequate hydration is always important, especially during intense training, but creatine itself is not the cause of dehydration.

The hair loss myth

The claim that creatine leads to hair loss is also a common fear. This idea arose from a single small study in 2009 involving rugby players, which showed an increase in dihydrotestosterone (DHT), a hormone linked to male pattern baldness.

What the science says: Later, more comprehensive reviews found no significant effect of creatine on DHT levels or any link to hair loss. Male pattern baldness is primarily determined by genetics, and the increase in DHT observed in the initial study remained within normal clinical limits.

Potential side effects of creatine and what to do

While the serious dangers are mostly myths, creatine can cause some minor side effects, especially at higher doses. These are generally a source of temporary discomfort and not a serious health risk.

  • Gastrointestinal distress: Bloating, diarrhea, or an upset stomach can occur, especially during the loading phase (e.g., 20 grams/day) or when taking a large single dose. Splitting the dose throughout the day and taking it with meals can help.
  • Temporary weight gain: Creatine draws water into the muscle cells, which can cause an initial increase in body weight, typically 2-5 pounds during the first week. This is water weight, not fat gain, and is a sign that the creatine is effectively saturating your muscles. Long-term weight gain is attributed to increased muscle mass from enhanced training.

Comparison: Creatine myths vs. facts

Feature Myth Fact
Kidney Damage Creatine harms the kidneys, especially long-term Long-term studies show no adverse effect on kidney function in healthy individuals
Dehydration Creatine causes dehydration and muscle cramps Studies show creatine may improve total body water and reduce the incidence of cramping
Hair Loss Creatine causes or accelerates hair loss No conclusive scientific evidence links creatine supplementation to hair loss
High Doses More creatine leads to better results Muscle creatine stores become saturated; excess creatine is simply excreted, and high doses increase risk of side effects like stomach upset
Safety in General Creatine is an unregulated, dangerous substance It is one of the most researched and safest supplements for healthy adults

Who should be cautious with creatine?

Although creatine is safe for most people, certain populations should consult a healthcare professional before use or avoid it altogether.

  • Individuals with pre-existing kidney or liver disease
  • People with diabetes, as creatine may affect blood sugar levels
  • Those with bipolar disorder, as it may worsen mania symptoms
  • Adolescents and children, due to insufficient long-term safety data in this population
  • Pregnant or breastfeeding women, as safety is not well established
  • Anyone taking medication that affects the kidneys

How to use creatine safely

To minimize potential discomfort and maximize benefits, follow these best practices for creatine supplementation:

  1. Use recommended doses: For healthy adults, a daily maintenance dose of 3–5 grams is typically sufficient to keep muscle stores saturated.
  2. Stay hydrated: Drink plenty of water throughout the day to support the increased water retention in your muscles and maintain overall hydration.
  3. Choose a quality product: Opt for third-party tested products (e.g., NSF Certified) to ensure purity and avoid contamination.
  4. Avoid a large loading dose: If you experience gastrointestinal distress during a loading phase (20g/day), skip it. A consistent, lower daily dose will achieve the same results over a few weeks.
  5. Be consistent: The most important factor for success is taking creatine every day, even on rest days, to keep muscle saturation high.

Conclusion

For most healthy adults, the research is clear: creatine is a safe and effective supplement with a minimal risk of side effects. Most of the 'dangers' associated with it are unfounded myths perpetuated by misinformation. By following recommended dosages, staying hydrated, and choosing a reputable product, individuals can safely benefit from creatine's performance-enhancing effects. However, those with pre-existing health conditions or specific concerns should always consult a medical professional before starting supplementation. For more information, read the position stand on the safety and efficacy of creatine by the International Society of Sports Nutrition.

Frequently Asked Questions

No, extensive research has shown that creatine does not cause kidney damage in healthy individuals. The confusion arises because creatine increases creatinine, a waste product, but this is a normal metabolic effect, not an indication of kidney dysfunction.

Scientific evidence refutes this myth. Studies indicate that creatine may actually improve total body hydration and reduce the incidence of muscle cramps and heat-related illness in athletes.

The initial weight gain is a temporary and normal side effect caused by increased water retention within the muscle cells, not fat gain. This is a sign that the creatine is effectively being absorbed and stored by your muscles.

If you have a history of kidney disease, liver disease, diabetes, or bipolar disorder, you should not take creatine without consulting a doctor first. Your healthcare provider can determine if it's safe for you.

To avoid stomach upset, bloating, or diarrhea, take a consistent maintenance dose of 3–5 grams per day rather than a large loading dose. You can also try splitting your daily dose or taking it with food.

No, there is no conclusive scientific evidence to support the claim that creatine causes hair loss. This myth is based on a flawed, small study and has been debunked by later research.

A loading phase (e.g., 20 grams/day for 5-7 days) can saturate muscles faster, but it is not necessary. A consistent daily dose of 3–5 grams will achieve the same level of muscle saturation over a few weeks and may be easier on your stomach.

References

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6
  7. 7
  8. 8
  9. 9

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.