The Inability to Digest Cellulose
At the heart of the matter is a complex carbohydrate called cellulose. Cellulose is a glucose polymer that forms the primary structural component of plant cell walls, giving grass its stiffness and rigidity. For the body to extract energy from any carbohydrate, it must first break it down into simple sugar units. In the case of starch, the chemical bonds are easily cleaved by the human enzyme amylase, which is present in saliva and the pancreas. However, the glucose units in cellulose are joined by a different type of bond, known as a beta-acetyl linkage.
Humans, like all mammals, simply do not possess the enzyme, known as cellulase, that is necessary to break these specific beta-acetyl bonds. Without cellulase, the large cellulose molecule remains intact and passes through our digestive tract mostly untouched. This is in stark contrast to herbivores, which have evolved unique ways to process this tough plant fiber.
The Complex Composition of Grass
Beyond just cellulose, grass is a composite material that presents further challenges to human digestion. A plant cell wall also contains other reinforcing polymers, such as hemicellulose and the incredibly durable lignin. Lignin is a complex aromatic polymer that binds to cellulose and hemicellulose, further increasing the cell wall's strength and resistance to degradation. This makes it difficult for any digestive process, even with cellulase, to access the energy stored within.
Furthermore, many grasses contain high levels of silica, a hard, abrasive compound that can cause significant wear and tear on teeth over time. Herbivores that graze on grass, such as cows, have specialized, continuously growing teeth to compensate for this constant abrasion, an adaptation that humans lack.
A Tale of Two Digestive Systems: Human vs. Ruminant
The most striking difference between humans and grass-eating animals lies in the structure and function of their digestive systems. Humans are monogastric (single-chambered stomach) omnivores, adapted for a varied diet of fruits, vegetables, grains, and meat. Ruminants, such as cows, are herbivores with a complex, four-chambered stomach specifically designed for processing fibrous plant material.
| Feature | Human Digestive System | Ruminant Digestive System |
|---|---|---|
| Stomach | Single-chambered | Four-chambered: Rumen, Reticulum, Omasum, Abomasum |
| Enzyme Source | Produced by the host (amylase, protease) | Symbiotic bacteria produce cellulase in the rumen |
| Digestion Process | Swift enzymatic and acidic breakdown in stomach and small intestine | Extensive fermentation by microbes in the rumen, followed by rumination |
| Cellulose Breakdown | None; passes as indigestible fiber | Efficiently broken down by microbes in the rumen |
| Nutrient Absorption | Primarily in the small intestine | Nutrients (like volatile fatty acids) absorbed in the rumen; microbial protein also digested |
In a cow's rumen, billions of symbiotic bacteria and other microorganisms produce cellulase and other enzymes, breaking down tough plant fibers through a fermentation process. The animal then regurgitates and re-chews this material, known as cud, to further break it down. This lengthy and specialized process allows the cow to absorb the volatile fatty acids produced by the microbes, which serve as its main source of energy.
The Role of Our Gut Microbiome
While humans can't produce cellulase, our own gut microbiome does contain some bacteria capable of fermenting insoluble fibers, including trace amounts of cellulose. These bacteria reside primarily in our large intestine, and their fermentation produces short-chain fatty acids (SCFAs), which can provide a small amount of energy to the host. However, this process is far less efficient than the system found in ruminants, and the amount of energy gained is minimal.
Furthermore, a 2024 study suggests that some cellulose-degrading bacterial strains, likely acquired from ruminant contact during the domestication of animals, are now becoming rare in industrialized societies. This suggests our modern, low-fiber diets have led to a loss of microbial diversity that could impact our gut health. The study authors speculate this might be why evidence for cellulose fermentation in the human gut is so scarce today. For more on this, see the study in Science.
What Happens When Humans Eat Grass?
If a human were to eat grass, it would pass through the digestive system mostly intact, acting as roughage or dietary fiber. This undigested fiber is beneficial for gut health in moderate amounts, aiding in regular bowel movements and contributing to satiety. However, consuming large quantities could cause digestive distress, bloating, and nutrient malabsorption. In times of extreme famine, people have reportedly consumed grass out of desperation, but it cannot sustain life due to its lack of bioavailable nutrients. Trying to subsist on a grass-only diet would lead to severe malnutrition and potentially life-threatening bowel perforation.
Conclusion: Our Omnivorous Design
The biological inability to digest grass is a testament to the specialized nature of our digestive system. Unlike herbivores designed to extract nutrients from fibrous plants, humans have evolved as omnivores, with a shorter intestinal tract and the enzymatic machinery to process a diverse diet. The key difference lies in the missing cellulase enzyme and the vastly different digestive anatomy. While we may share some symbiotic gut bacteria with herbivores, our capacity to break down cellulose remains insignificant. Our primary nutritional intake comes from digestible carbohydrates, proteins, and fats, not the tough cell walls of the plants around us. Though grass can act as a source of fiber, attempting to use it as a primary food source is a futile and dangerous endeavor.