Can You Take Two Types of Collagen at the Same Time?

January 7, 2026 •

3 min read

According to scientific research, the human body is composed of over 28 different types of collagen, but types I, II, and III are the most prevalent. This diversity has led to a common question: can you take two types of collagen at the same time? The short answer is yes, and for many people, combining different collagen types can offer a more comprehensive range of benefits.

Quick Summary

It is generally safe to take multiple types of collagen simultaneously, but for the best results, timing and compatibility are key considerations. Combining Types I and III is synergistic for skin health, while Type II is most effective for joint support when taken separately. Combining types can address multiple health goals effectively, but it is important to adhere to dosage recommendations to maximize absorption and benefits.

Key Points

Combine Type I and III for Skin: Taking Type I (like marine) and Type III (like bovine) together supports synergistic benefits for skin, hair, and nails.
Isolate Type II for Joints: For optimal absorption and targeted support for cartilage and joints, Type II collagen should be taken at a different time from Type I and III.
Multi-Collagen Blends May be Ineffective: Supplements that combine all types into one dose may compromise the absorption of Type II collagen due to its specific interaction with the body.
Sourcing Matters Most: The quality and sourcing of your collagen (e.g., grass-fed, sustainably-sourced) are more important for effectiveness than simply including multiple types.
Listen to Your Body: Start with one type to see how your body responds before combining, and always adhere to recommended dosages.
Enhance Benefits with Hydration and Vitamin C: Ensure proper hydration and sufficient vitamin C intake, as these are crucial for your body's natural collagen synthesis.

Understanding Collagen's Role and Types

Collagen is the body's most abundant protein, providing structure, strength, and elasticity to connective tissues like skin, bones, tendons, and cartilage. Not all collagen is the same; different types have unique functions and locations. Common types in supplements are:

Type I: Found in skin, bones, tendons, and ligaments, providing structure. Marine and bovine collagen are rich sources.
Type II: The main component of cartilage, supporting joint health. Chicken collagen is a common source.
Type III: Found with Type I in skin, blood vessels, and organs, aiding elasticity and firmness. Bovine and porcine collagen are good sources.

The Compatibility of Different Collagen Types

While combining different collagen types is safe, timing matters for optimal benefits.

Combining Type I and Type III

Types I and III often appear together in supplements and work synergistically for skin elasticity and hydration. Bovine collagen naturally contains both. There's no evidence they compete for absorption when taken together.

Timing for Type II Collagen

Type II collagen is processed specifically for joint health. Some research suggests it's best absorbed and utilized separately from Types I and III for optimal joint support. Taking Type II collagen in the morning and a Type I/III combination later is often recommended.

The Benefits of Strategic Combination

Combining different collagen types can address multiple health goals. For example, taking a Type I/III supplement with a separate Type II supplement targets both skin and joint health. Mixing marine and bovine collagen (both Type I and III) can enhance support for skin and connective tissues.

Comparison of Collagen Types


Feature	Type I Collagen (Marine/Bovine)	Type II Collagen (Chicken/Bovine)	Type III Collagen (Bovine/Porcine)
Primary Function	Provides structure for skin, bones, and tendons.	Supports cartilage and joint cushioning.	Enhances skin elasticity and organ health.
Source	Fish skin and scales (marine); cow hide and bones (bovine).	Chicken cartilage; some bovine cartilage.	Cow hide and bones (bovine); pig skin (porcine).
Best for	Skin elasticity, hair, nails, bone density.	Joint pain, arthritis, cartilage support.	Skin firmness, blood vessels, organs.
Compatibility	Compatible with Type III.	Best taken separately from Types I and III.	Compatible with Type I.
Absorption	Highly bioavailable when hydrolyzed.	Best absorbed separately, often in undenatured form.	High bioavailability with Type I.

How to Choose and Combine

Consider your health goals when choosing collagen. For skin, hair, and nails, Type I and III are good. For joint support, add a separate Type II supplement.

Read the Label: Check types and dosage. Look for 'hydrolyzed' or 'collagen peptides' for better absorption.
Prioritize Quality: Choose reputable brands with quality sourcing. Quality matters more than the number of types.
Listen to Your Body: Start with one type and observe results before adding another. Consistency is key.

Conclusion

Yes, you can take two types of collagen at the same time for a holistic approach. Understanding the functions and interactions of each type is key. Combining Type I and Type III supports skin health, while Type II is best taken separately for joint benefits. Focusing on product quality and timing allows you to effectively integrate multiple collagen types into your routine. Always consult a healthcare professional for personalized advice. For more information on collagen types and functions, see this resource: What are the different types of collagen? Types of collagen and its functions.

Frequently Asked Questions

Yes, it is generally safe to take two types of collagen at the same time. However, for optimal absorption, it is often recommended to separate the intake of Type II collagen from Types I and III.

Combining all three types can be done safely, but some experts suggest separating the intake of Type II collagen, as its absorption mechanism can be hindered by the presence of Types I and III. Taking them at different times, such as Type II for joints in the morning and Types I/III for skin later, can maximize benefits.

Yes, marine and bovine collagen can be mixed. This is a common practice that provides a broader range of amino acids and collagen types (both primarily Type I and III) to support skin, joints, and gut health comprehensively.

A multi-collagen supplement can be convenient, but for specific needs, taking separate types is often more effective. Some multi-collagen blends may contain Type II collagen, which is best absorbed alone. The overall quality and absorbability of the collagen matter more than the number of types.

For maximum benefit, consider staggering your intake. A popular schedule is to take Type II collagen (for joints) in the morning and a Type I/III blend (for skin and hair) in the evening.

Types I and III are highly compatible and do not compete significantly. However, Type II collagen, especially in its undenatured form, utilizes a different absorption pathway related to immune response and is more effective when taken separately from other types.

Always adhere to the recommended dosages on the packaging of each supplement. Combining should not result in exceeding the total daily intake. Most collagen supplements suggest a daily intake of 2.5 to 15 grams, depending on the specific product and formulation.