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Does Bovine Growth Hormone Affect Humans?

3 min read

According to the U.S. Food and Drug Administration (FDA), bovine growth hormone (bGH) is a large protein that is safely broken down during human digestion. This is a key reason why scientists and regulatory bodies conclude that bovine growth hormone does not biologically affect humans.

Quick Summary

This article explains how bovine growth hormone is inactive in humans due to its species-specific nature and breakdown during digestion. It addresses concerns related to higher IGF-1 levels in milk from treated cows and the increased risk of mastitis, referencing findings from major health organizations.

Key Points

  • Biologically Inactive: Bovine growth hormone (bGH) is a species-specific protein that is not biologically active in humans.

  • Digestion Deactivates bGH: Human digestive enzymes break down bGH into inactive amino acid fragments, preventing it from being absorbed intact.

  • Pasteurization Destroys Hormones: The high heat of pasteurization and cooking denatures and destroys most of the bGH in milk and meat.

  • IGF-1 Intake is Negligible: While rBST increases IGF-1 in milk, the amount consumed is minuscule compared to what the human body produces naturally and absorbs minimally.

  • Regulatory Approval: Health organizations like the FDA, WHO, and NIH have concluded that milk and meat from rBST-treated cows are safe for human consumption.

  • Potential for Antibiotic Use: Use of rBST can increase a cow's risk of mastitis, potentially leading to more antibiotic use and contributing to antibiotic resistance, a secondary public health concern.

  • No Significant Nutritional Difference: The overall nutritional composition of milk from rBST-treated and untreated cows is virtually identical.

In This Article

Understanding Bovine Growth Hormone (bGH) and rBST

Bovine growth hormone (bGH), also known as bovine somatotropin (bST), is a naturally occurring protein hormone in cattle that regulates metabolic processes and stimulates milk production. Recombinant bovine somatotropin (rBST or rBGH) is a genetically engineered version used to increase milk yield. Its use has prompted public concern about potential impacts on human health.

The Science Behind Human Safety

Major health and food safety organizations like the FDA and WHO have long stated that consuming dairy and meat from rBST-treated cows is safe. This is primarily because bGH is a large protein biologically active only in cattle and similar species, meaning it cannot bind to human growth hormone receptors. Furthermore, human digestion breaks down bGH and rBST into inactive fragments, preventing absorption. Pasteurization and cooking also help deactivate the hormone.

The Role of IGF-1

Concerns about rBST often involve Insulin-like Growth Factor-1 (IGF-1), as rBST can increase IGF-1 in cow's milk. Some worry higher IGF-1 intake could pose a health risk, but IGF-1 from milk is largely broken down during digestion and has little biological effect orally. The amount of IGF-1 from milk is also minimal compared to what the human body produces naturally. IGF-1 levels in milk from rBST-treated cows are generally within the normal range found in milk from untreated cows and human breast milk.

Comparing Milk from Treated vs. Untreated Cows

Feature Conventional Milk (Potentially rBST-treated) Organic Milk (No rBST)
Bovine Growth Hormone (bGH/rBST) May contain synthetic rBST (though many dairies stopped use voluntarily), along with naturally occurring bGH. Does not contain synthetic rBST, but has naturally occurring bGH.
Insulin-like Growth Factor-1 (IGF-1) May have slightly higher levels due to rBST, but still within the normal range. Contains naturally occurring IGF-1.
Nutritional Composition Generally comparable to organic milk nutritionally. May have a better fatty acid profile due to diet/grazing.
Antibiotic Residues Tested; milk exceeding tolerance is prohibited. Increased mastitis from rBST could potentially increase antibiotic use, though national data shows no increased human exposure risk. No antibiotics used, thus no residues.
Animal Welfare Concerns rBST linked to increased mastitis and other health issues. Adheres to stricter animal welfare standards.

Potential for Increased Antibiotic Resistance

While bGH is not a direct human health risk, rBST use can increase a cow's risk of mastitis, potentially leading to more antibiotic use. This raises concerns about antibiotic resistance, which are monitored by regulatory bodies. Despite concerns, national data indicates a decline in antibiotic residue violations.

Conclusion

Scientific and regulatory bodies agree that bovine growth hormone does not affect humans through milk or meat consumption. It is species-specific, inactive in humans, and broken down by digestion and processing. While rBST slightly increases IGF-1 in milk, the amount and minimal absorption are unlikely to impact human health. Concerns about animal welfare and potential antibiotic use from increased mastitis are valid and have led some countries to ban rBST based on animal health rather than human safety. Consumer choices between conventional and organic milk often involve personal values, agricultural practices, and cost, more than direct human health risks from bGH itself.

Food and Drug Administration: Bovine Somatotropin (bST)

Frequently Asked Questions

No, according to extensive scientific review by major health organizations, recombinant bovine somatotropin (rBST) is not considered a human health hazard. It is a species-specific protein that is broken down during human digestion.

There is no conclusive evidence that bovine growth hormone (bGH) causes cancer in humans. While bGH treatment in cows slightly increases Insulin-like Growth Factor-1 (IGF-1), the amount absorbed by humans from dairy is biologically insignificant.

rBST has been banned in many countries, including the European Union and Canada, based on animal welfare concerns, not human safety risks. The increased milk production can stress cows and increase the risk of mastitis, though some argue the bans are also political or economic.

Yes, milk from rBST-treated cows can have slightly higher levels of IGF-1. However, this increase is typically within the normal physiological range seen in milk and is not considered a human health risk due to minimal oral absorption.

The human digestive system breaks down bGH just like any other protein, rendering it inactive. It is not absorbed intact, so it cannot exert any hormonal effect on the human body.

No milk is truly hormone-free, as cows naturally produce bGH, which is present in all milk. Organic milk does not contain synthetic rBST, but it still contains the naturally occurring bovine growth hormone.

About 90% of the bST and rBST in milk is destroyed during the pasteurization process, which involves high heat treatment to kill harmful bacteria. This further reduces any potential exposure to the hormone.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.