The Connection Between Diet, Inflammation, and HS
Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition, and inflammation is at the heart of its painful symptoms. For many years, treatment focused solely on medication and surgery. However, increasing evidence suggests that dietary choices and overall lifestyle can significantly impact disease severity. The food we eat can either exacerbate or mitigate the inflammatory response in our bodies. In individuals with HS, certain dietary patterns may trigger immune dysregulation, leading to follicular blockages and painful flares.
How Diet Influences HS
Foods with a high glycemic index (GI), such as refined carbohydrates and sugars, can cause rapid spikes in blood sugar and insulin. For those with HS, this can be problematic, as insulin resistance is more prevalent among patients with the condition and can worsen symptoms. Moreover, certain trigger foods have been identified by many patients through personal trial and error, as well as in some research. Dairy products, for instance, contain hormones and proteins that can contribute to follicular inflammation. Brewer's yeast, found in baked goods and fermented drinks, has also been shown to worsen symptoms in some individuals. By contrast, a diet rich in anti-inflammatory foods like fruits, vegetables, and omega-3 fatty acids can help reduce overall inflammation.
The Anti-Inflammatory Effects of Fasting
Fasting, particularly intermittent fasting, has gained traction for its potential health benefits, including reducing inflammation and improving insulin sensitivity. During periods of fasting, the body can shift its focus from digestion to cellular repair processes, known as autophagy. This natural process involves clearing out damaged cells and is believed to have a positive impact on the body's inflammatory state. By reducing the frequency and duration of eating, fasting may help stabilize blood sugar and insulin levels, addressing a key factor linked to HS flares.
What the Research Says: Fasting and HS
Intermittent Fasting and HS Severity
One of the most cited studies on fasting for HS involved participants observing Ramadan, a form of intermittent, time-restricted eating. A 2019 study published in Nutrients found that 60 HS patients experienced a significant decrease in their disease severity score (IHS4) after a month of Ramadan fasting. Interestingly, this improvement was not directly associated with weight loss, suggesting that other metabolic or hormonal factors related to the fasting pattern may be responsible. While the results are promising, it is important to note that these were small-scale studies and the benefits observed sometimes subsided after the fasting period ended. This highlights the need for a consistent, sustainable approach to dietary management.
Comparison of HS Dietary Approaches
Dietary management of HS is not a one-size-fits-all solution. Various approaches exist, each with a different focus. The table below compares fasting with other popular dietary strategies for managing HS symptoms.
| Dietary Approach | Primary Mechanism | Evidence for HS | Key Considerations | 
|---|---|---|---|
| Intermittent Fasting | Reduces inflammation, improves insulin sensitivity, cellular repair. | Promising pilot study results (Ramadan fasting) showed reduced severity scores. | Individual responses vary; benefits may subside after fasting ends; requires medical supervision, especially for longer fasts. | 
| Mediterranean Diet | Anti-inflammatory properties from high fiber, omega-3s, and antioxidants. | Associated with lower HS severity and offers overall health benefits. | A sustainable, well-researched, and relatively easy dietary shift for most people. | 
| Elimination Diets | Identifies and removes specific food triggers, such as dairy, yeast, or nightshades. | High success rate for identifying personal triggers; 70% of patients saw improvement on a yeast-elimination diet. | Can be restrictive and requires careful reintroduction to pinpoint triggers; often needs guidance from a doctor or dietitian. | 
| Ketogenic Diet | Lowers insulin levels by restricting carbohydrates; may improve gut microbiota and inflammation. | Pilot studies in overweight women showed reduced HS severity and metabolic improvements. | Highly restrictive and not suitable for everyone; requires medical supervision to prevent nutritional deficiencies. | 
Practical Guidelines for Considering Fasting
Before starting any new dietary regimen, especially fasting, it is crucial to consult a healthcare provider or a dietitian who understands HS. They can help you develop a safe and effective plan tailored to your specific needs and medical history.
How to Approach Fasting Safely
- Start with time-restricted eating: The 16:8 method (fasting for 16 hours, eating within an 8-hour window) is a common starting point and can be more manageable.
- Time it right: Try to align your eating window with natural circadian rhythms.
- Listen to your body: It can take several weeks for your body to adjust to fasting. Pay attention to any adverse effects and adjust your schedule as needed.
- Avoid extremes: Prolonged, unsupervised fasts are not recommended and may be dangerous, potentially causing nutritional deficiencies.
Combining Fasting with an Anti-Inflammatory Diet
During your eating windows, focusing on nutrient-dense, anti-inflammatory foods can maximize the benefits. Conversely, reintroducing trigger foods can negate any positive effects of the fasting period. Focus on the following:
- Foods to eat: Plenty of fresh fruits and vegetables, whole grains, omega-3 rich fish (like salmon), legumes, and healthy fats (such as avocado and olive oil).
- Foods to consider avoiding: Dairy products, high-sugar foods (including refined carbs), processed meats, and brewer's yeast.
- Hydration is key: Drink plenty of water and calorie-free beverages during your fasting period to stay hydrated and manage hunger.
The Importance of a Food Diary
Keeping a food diary is one of the most effective tools for identifying personal triggers and monitoring your response to dietary changes. By tracking what you eat and drink, along with your symptoms, you can uncover patterns that are unique to your condition. Share this information with your doctor to help refine your HS management strategy.
Conclusion: Is Fasting Right for Your HS?
For some people with HS, fasting can be a useful tool to help manage symptoms by targeting underlying inflammation and metabolic factors. Studies, including those on Ramadan fasting, have demonstrated a reduction in HS severity scores, but these results are not universal and benefits can wane. Fasting is not a cure and should be viewed as one component of a holistic treatment plan, alongside medical therapy, weight management, and other lifestyle modifications. The most successful approach involves consulting a healthcare professional, patiently observing your body's response, and maintaining a healthy, anti-inflammatory eating pattern, whether incorporating fasting or not. For a more detailed look at the study on Ramadan fasting and its effects on HS, consult this scientific publication: The Safety and Impact of a Model of Intermittent, Time-Restricted, Ramadan Fasting in Patients with Hidradenitis Suppurativa.