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Does Natto Have Any Side Effects? What You Need to Know

4 min read

Despite being a Japanese superfood consumed for thousands of years, the strong taste and potent health benefits often lead people to question: does natto have any side effects? While it's celebrated for its rich vitamin K2 and probiotic content, certain individuals must exercise caution due to its unique properties.

Quick Summary

Though packed with nutrients, natto can cause issues for those with soy allergies, digestive sensitivities, or those on specific medications. Moderation is key.

Key Points

  • Blood Thinner Interaction: Natto contains high levels of vitamin K2 and nattokinase, which can interfere with anticoagulant medications like warfarin.

  • Soy Allergy: Individuals with a soy allergy should avoid natto completely, as it is a fermented soybean product.

  • Digestive Discomfort: Due to its high fiber and probiotic content, consuming large amounts of natto can cause initial bloating, gas, or diarrhea.

  • Thyroid Function: Natto is a goitrogen, and people with poorly functioning thyroids (hypothyroidism) should consume it in moderation.

  • Consult a Doctor: Always talk to a healthcare provider before adding natto to your diet, especially if you have a pre-existing medical condition or take prescription medication.

  • Start Slow: To minimize digestive issues, introduce natto into your diet in small portions and gradually increase your intake as your body adjusts.

In This Article

Understanding the Common Risks and Side Effects

While natto is a powerhouse of nutrition, it is not without potential downsides, particularly for certain groups of people. Understanding these risks is crucial for safe consumption.

Risk of Interaction with Medications

One of the most significant concerns surrounding natto is its interaction with medications, especially blood thinners. The enzyme nattokinase, produced during the fermentation process, has potent fibrinolytic (clot-dissolving) properties, essentially acting as a natural blood thinner. Additionally, natto is one of the richest food sources of Vitamin K2, a nutrient essential for blood clotting. This creates a complex situation for individuals on anticoagulant drugs like Warfarin, which require careful regulation of vitamin K intake. The varying levels of vitamin K2 in natto can destabilize the effect of these medications, potentially leading to dangerous bleeding or excessive clotting. For this reason, anyone on such medication should consult their doctor before consuming natto.

Furthermore, natto's nattokinase may lower blood pressure. This can pose a risk for individuals already on blood pressure medication, as the combined effect could cause blood pressure to drop too low. It is essential for these individuals to monitor their blood pressure closely and discuss the dietary change with a healthcare provider.

Digestive Concerns and Allergies

For those new to natto, digestive issues are a common side effect. The high fiber content, while beneficial in the long run, can cause gas, bloating, and diarrhea as the body adjusts to the change in gut flora. Starting with very small portions and gradually increasing intake can help minimize these symptoms. In rare cases, individuals without a general soy allergy may develop a specific late-onset hypersensitivity reaction to natto, but this is uncommon. Of course, anyone with a known soy allergy should avoid natto entirely, as it is a fermented soybean product. Symptoms can range from mild rashes to severe allergic reactions.

Considerations for Thyroid Health

Soy is considered a goitrogen, a substance that can interfere with the normal function of the thyroid gland. While the effect is typically mild in healthy individuals, it is a concern for people with hypothyroidism, or an already impaired thyroid. The fermentation process in natto may reduce the level of goitrogens, but caution is still advised. Anyone with a thyroid condition should consult a doctor before incorporating natto into their regular diet.

Special Population Groups

Certain individuals should be particularly cautious or avoid natto altogether:

  • Pregnant and Breastfeeding Women: Due to a lack of sufficient data on safety, consumption should be limited to food amounts, or avoided.
  • Children and Adolescents: Similar to pregnancy, there is insufficient study data to recommend nattokinase supplements, and caution is advised for regular consumption of the food.
  • Pre-Surgery Patients: Because of its blood-thinning properties, consuming natto should be stopped at least two weeks before any scheduled surgery.

Natto vs. Nattokinase Supplements: A Comparison

Nattokinase supplements are available for those who want the heart health benefits of the enzyme without consuming the whole fermented food. However, there are important distinctions to be aware of.

Feature Whole Natto Nattokinase Supplement
Form Fermented soybean food Powder, capsule, or tablet
Key Components Probiotics, high Vitamin K2, fiber, protein, nattokinase Concentrated nattokinase enzyme, often with Vitamin K2 removed
Effect on Blood Combines blood-thinning effect (nattokinase) and clotting effect (Vitamin K2) Primarily blood-thinning effect
Medication Interaction High risk, especially with Warfarin and other anticoagulants Moderate to high risk, especially with anticoagulants and blood pressure medication
Best For Healthy individuals seeking diverse nutrients and probiotics Individuals seeking the targeted effects of the enzyme, only under medical supervision

Is Natto for Everyone? Balancing Benefits and Risks

For the average, healthy individual, the benefits of natto generally outweigh the risks. The high protein, fiber, and probiotic content support gut health, while Vitamin K2 is beneficial for bone health. The risks, when managed correctly, are minimal. However, individuals with pre-existing conditions, particularly cardiovascular or thyroid issues, or those on certain medications must approach natto with caution and medical guidance. Always be transparent with your doctor about all dietary changes and supplements, especially if they are potent as natto. The key to incorporating this unique superfood into your diet safely is moderation and an understanding of your own health needs. For most, a small serving a few times a week is an excellent way to reap its nutritional rewards without undue risk.

The Role of Moderation and Preparation

To minimize potential side effects, start with a small amount of natto, perhaps a tablespoon mixed with rice, and observe how your body reacts. You can gradually increase the portion size over time. The fermentation process makes the nutrients in natto more bioavailable and easier to digest than unfermented soy, so it is often better tolerated than other soy products. Some people find the distinctive taste and texture to be a hurdle. Mixing natto with other strong flavors, such as a traditional sauce, mustard, or kimchi, can help mask the intensity. Freeze-dried natto is also an option for those who want the benefits without the typical stringy, sticky texture.

Conclusion

Natto, a venerable fermented superfood from Japan, offers a compelling profile of nutrients that support heart, bone, and digestive health. The enzyme nattokinase and high vitamin K2 content are particularly noteworthy for their potential benefits. However, it is precisely these potent components that also give rise to the most significant side effects, primarily the risk of interaction with blood-thinning medication. Digestive issues, soy allergies, and thyroid concerns are also valid considerations. For the general population, natto is a healthy and safe addition to a balanced diet, provided it is consumed in moderation. Those with specific medical conditions must consult a healthcare professional to determine if natto is appropriate for them. By understanding the potential risks and practicing moderation, many people can enjoy the remarkable health benefits of this unique and ancient food. For more detailed information on nattokinase in supplements, see this resource from Drugs.com, though always consult a doctor.

Frequently Asked Questions

While natto is exceptionally high in vitamin K2, the risk of toxicity from food sources is minimal. The primary concern is its interaction with blood-thinning medications like warfarin, not an excess of the vitamin itself.

For healthy individuals, moderate daily consumption of natto is generally safe and offers many benefits. However, those with specific health conditions or on certain medications should consult a doctor before making it a daily habit.

Heating natto can destroy the nattokinase enzyme, which has blood-thinning properties. However, it does not remove the vitamin K2, which is also a concern for those on anticoagulants, so heating does not eliminate all risks.

Yes. Whole natto contains both vitamin K2 and nattokinase, while some supplements are formulated to remove vitamin K2. However, both can interact with blood thinners, and a doctor should be consulted for either.

Yes, as nattokinase has blood-pressure-lowering effects, people with low blood pressure or those taking blood pressure medication should monitor their intake and consult a doctor to avoid blood pressure dropping too low.

Anyone with a known soy allergy should avoid natto completely, as it is a fermented soybean product and can cause an allergic reaction.

To reduce gas and bloating, start with a very small portion of natto to allow your digestive system to adjust to the high fiber and probiotics. Gradually increase the amount over time.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.