Skip to content

Does Tube Feed Need to be Refrigerated? Your Complete Guide to Safe Storage

4 min read

Improper storage of tube feeding formula can lead to bacterial growth and serious illness. Understanding when and why you need to refrigerate tube feed is crucial for patient safety and maintaining nutritional integrity for individuals relying on enteral nutrition.

Quick Summary

Opened tube feeding formula must be tightly sealed and refrigerated, while unopened containers can be stored at room temperature. Adhering to strict hang time limits is also essential to prevent bacterial contamination and ensure patient safety during feedings.

Key Points

  • Refrigerate Opened Formula: Once a container is opened, unused liquid or mixed powdered formula must be refrigerated in a covered container and used within 24 hours.

  • Store Unopened Formula at Room Temperature: Unopened, shelf-stable cans or containers do not require refrigeration and should be stored in a cool, dry place until the expiration date.

  • Observe Hang Time Limits: Pay close attention to the maximum time a formula can safely hang in a feeding bag at room temperature (e.g., 8-12 hours for liquid, 4 hours for powdered).

  • Never Microwave Formula: Do not heat formula in a microwave, as it can create dangerous hot spots and destroy nutrients. Let refrigerated formula warm to room temperature on the counter instead.

  • Discard Old Formula: Throw away any formula that has been open for more than 24 hours, has exceeded its maximum hang time, or has passed its expiration date.

  • Practice Strict Hygiene: Prevent bacterial contamination by washing your hands and cleaning your workspace and equipment thoroughly before each feeding.

In This Article

Understanding Tube Feed Refrigeration

At its core, tube feeding formula is a liquid food product, and like other foods, its safety is highly dependent on proper handling and storage. The simple answer to whether tube feed needs to be refrigerated depends on its state: has it been opened? Unopened, shelf-stable formulas are designed to be stored in a cool, dry place at room temperature. However, once a container of liquid formula has been opened, or if powdered formula has been mixed, it is immediately susceptible to bacterial contamination and must be refrigerated. This is a critical distinction that all caregivers and patients must understand to prevent foodborne illness.

The 24-hour rule is a standard guideline for most liquid formulas once they are opened. After this period, any unused portion, even if refrigerated, must be discarded. This is because even at cold temperatures, bacteria can still grow and reach unsafe levels over time. A common cause of gastrointestinal distress, such as diarrhea, in tube-fed patients is bacterial overgrowth from improperly stored or handled formula.

Safe Storage for Different Formula Types

Proper storage procedures vary slightly depending on the type of formula being used. Below are the key guidelines for each common format.

Unopened Formula

  • Location: Store in a clean, cool, and dry place, away from direct sunlight or sources of heat like radiators.
  • Duration: Follow the expiration date printed on the packaging.
  • Best Practice: Organize your supplies to use the oldest stock first.

Opened Liquid Formula

  • Refrigeration is required: Once opened, all unused liquid formula must be covered, sealed, and immediately placed in the refrigerator (at a temperature below 4°C/40°F).
  • Duration: Opened formula should be used within 24 hours of opening. Any leftover formula after this period must be discarded.

Powdered Formula

  • Preparation: Only mix the amount of powdered formula needed for the next 24 hours. Once mixed with water, it must be treated like an opened liquid formula.
  • Storage: Unmixed powder should be stored in its original, sealed container in a cool, dry place. The container should be covered once opened.
  • Duration: Mixed formula must be refrigerated and used within 24 hours.

Homemade or Blended Feeds

  • Special Considerations: Blending food increases the risk of rapid bacterial growth. These feeds are significantly more sensitive to temperature and should be handled with extreme care.
  • Duration: Always follow the specific instructions from your healthcare provider or dietitian regarding storage and use times for homemade formulas, as they are often much shorter than 24 hours.

Hang Time Rules and Preventing Contamination

"Hang time" is the maximum amount of time a formula can safely remain at room temperature after being poured into a feeding bag or set. These limits exist to minimize the risk of bacteria multiplying to unsafe levels.

  • Ready-to-use liquid formula: A typical hang time is 8 to 12 hours.
  • Powdered formula (mixed): A shorter hang time of 4 hours is often recommended due to its non-sterile nature.
  • Blended or homemade feeds: Due to higher bacterial risk, these have the shortest hang times, sometimes as little as 2 hours.

To prevent contamination, it is crucial to never add fresh formula to a feeding bag that already contains leftover formula. Always start with a clean feeding bag and fresh formula for each feeding session or hang time period. For example, if your formula has an 8-hour hang time, any leftover formula in the bag after 8 hours must be discarded.

Safely Warming Refrigerated Formula

While you should not feed cold formula to avoid gastrointestinal upset, you must also never use a microwave to warm tube feed. Microwaving creates uneven hot spots that can harm the patient and can also destroy vital nutrients in the formula. The safest method is to let the refrigerated formula stand at room temperature for about 30 minutes before feeding. Another option is to place the can or container of formula in a bowl of warm water for a few minutes.

Proper Hygiene and Handling Procedures

Maintaining excellent hygiene is paramount to preventing infection when preparing and administering tube feeds.

  • Wash hands: Always wash your hands thoroughly with soap and water before handling any formula or equipment.
  • Clean workspace: Prepare your feeds on a clean, dry surface.
  • Clean equipment: Wash feeding sets, syringes, and containers with warm, soapy water after each use and allow them to air dry. Replace feeding bags and sets every 24 hours.
  • Inspect formula: Before opening, check the expiration date and inspect the can or bottle for any damage. Shake the container well before opening.
Storage Factor Unopened Formula Opened/Mixed Formula
Location Cool, dry place (pantry) Covered and refrigerated (less than 4°C)
Container Original manufacturer's packaging Sealed, covered container (original or separate)
Duration Until expiration date Up to 24 hours
Feeding Temperature Room temperature Warmed to room temperature (not microwaved)
Contamination Risk Low (if sealed) High (discard leftovers after 24 hrs or hang time)

Conclusion: Prioritizing Safety in Tube Feeding

Refrigeration is a necessary step in the safe storage of any tube feed that has been opened or mixed, while unopened containers are stable at room temperature. Adhering to strict timelines—using opened formula within 24 hours and observing maximum hang times—is critical for preventing dangerous bacterial growth. Always practice meticulous hygiene, never microwave formula, and follow your healthcare provider's specific instructions. By following these straightforward guidelines, you can ensure the highest standard of safety and care for the patient. For further guidelines, consult a reliable medical resource such as a hospital factsheet on tube feeding.

Frequently Asked Questions

The duration depends on the type of formula. Opened, ready-to-use liquid formulas typically have a maximum hang time of 8-12 hours at room temperature, while mixed powdered formulas are limited to 4 hours. Follow your specific formula's instructions.

Yes, but you must do so safely. Take the formula out of the refrigerator about 30 minutes before feeding to let it reach room temperature. Alternatively, place the container in a bowl of warm (not hot) water. Never use a microwave to warm tube feed.

Immediately cover or reseal the opened can and place it in the refrigerator. The unused portion must be used or discarded within 24 hours.

Hang time is the maximum amount of time that prepared tube feeding formula can be left at room temperature in a feeding bag or syringe. It is important because it limits the time bacteria have to grow and contaminate the feed.

No. Never add fresh formula to a bag that already contains old formula. This practice can introduce bacteria and is a major safety risk. Always use a clean bag with fresh formula.

If opened formula has been left at room temperature for longer than its maximum recommended hang time, it should be discarded to prevent the risk of bacterial contamination and illness.

Unmixed powdered formula does not need to be refrigerated and should be stored in a cool, dry place. However, once you mix the powder with water, the resulting liquid formula must be refrigerated and treated with the same 24-hour rule as opened liquid formula.

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.