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Essential Fatty Acids: Which Fatty Acids Cannot Be Synthesized By The Body And Should Be Supplied In The Diet Known As?

3 min read

The human body possesses the remarkable ability to synthesize most of the fatty acids it needs to function, but there are certain polyunsaturated fatty acids it cannot produce on its own. These vital nutrients, appropriately known as essential fatty acids, must be supplied through your diet to support crucial physiological functions.

Quick Summary

Essential fatty acids, including the parent omega-3 (alpha-linolenic acid) and omega-6 (linoleic acid) fats, are polyunsaturated fats the body cannot create and must obtain from food for proper cellular function.

Key Points

  • Essential Fatty Acids (EFAs): These are fats the body cannot produce and must be supplied by the diet, including alpha-linolenic acid (omega-3) and linoleic acid (omega-6).

  • Crucial Cellular Building Blocks: EFAs are integral components of all cell membranes, influencing their fluidity and overall function, which is critical for every cell in the body.

  • Brain and Nerve Health: Derivatives of omega-3s, particularly DHA, are essential for proper brain and nervous system development and function, from fetal development through adulthood.

  • Inflammation Regulation: EFAs are precursors to eicosanoid signaling molecules, which control inflammation. The balance between anti-inflammatory omega-3s and potentially pro-inflammatory omega-6s is crucial for health.

  • Balanced Dietary Intake: Modern diets often feature too high a ratio of omega-6 to omega-3. Increasing intake of fatty fish, flaxseed, and walnuts can help correct this imbalance.

  • Avoids Deficiency: While rare, EFA deficiency can lead to skin problems like dermatitis, poor wound healing, and slowed growth.

In This Article

What Are Essential Fatty Acids?

Essential fatty acids (EFAs) are vital polyunsaturated fatty acids (PUFAs) that the human body cannot synthesize. This is due to the lack of specific enzymes needed to introduce double bonds at certain positions in the fatty acid chain. The two main families of EFAs are omega-3 and omega-6, named based on the location of the first double bond from the methyl end.

The Role of Essential Fatty Acids

EFAs serve multiple critical functions in the body:

  • Cell Membrane Structure: They are components of cell membranes.
  • Brain and Nervous System: Omega-3 derivatives are crucial for brain and visual development and function.
  • Signaling Molecules: EFAs are precursors to eicosanoids, which regulate inflammation, blood clotting, and immune responses. The balance of omega-3 and omega-6 intake affects these responses.

Omega-3 vs. Omega-6: The Crucial Balance

The two primary EFAs are alpha-linolenic acid (ALA), an omega-3, and linoleic acid (LA), an omega-6. Maintaining a healthy balance between these is vital. Western diets often have a high omega-6 to omega-3 ratio, potentially increasing inflammation. This is partly because they compete for the same metabolic enzymes, and excessive omega-6 can hinder omega-3's beneficial effects.

EFA Derivatives: Conditionally Essential

While ALA and LA are strictly essential, their derivatives like EPA, DHA (from omega-3), and AA (from omega-6) are often considered conditionally essential. This is because the body's conversion of ALA to EPA and DHA can be inefficient, making direct dietary intake from sources like fatty fish important.

For a detailed breakdown of Omega-3 vs. Omega-6 features, parent fatty acids, key derivatives, common sources, primary functions, and typical ratios in the Western diet, refer to the information available from {Link: Linus Pauling Institute https://lpi.oregonstate.edu/mic/other-nutrients/essential-fatty-acids}.

Dietary Sources of Essential Fatty Acids

To ensure adequate EFA intake, include a variety of foods in your diet:

Omega-3 Fatty Acid Sources

  • ALA (Plant-Based): Flaxseed, chia seeds, walnuts, hemp seeds, and leafy greens.
  • EPA and DHA (Marine-Based): Fatty fish like salmon and mackerel, and algae oil for vegetarians/vegans.

Omega-6 Fatty Acid Sources

  • LA (Plant-Based): Oils such as safflower, sunflower, and corn oil, and most nuts and seeds.

Maintaining Balance To balance a high omega-6 intake, increase omega-3 consumption. The American Heart Association recommends eating fatty fish twice weekly. Plant-based options like flaxseed and walnuts, or algae oil supplements, can also help achieve a healthier balance.

Conclusion

Essential fatty acids, specifically alpha-linolenic acid (omega-3) and linoleic acid (omega-6), cannot be made by the body and must come from the diet. These PUFAs are crucial for cell structure, brain function, and regulating processes like inflammation. Given the body's limited ability to convert plant-based EFAs to their active forms, a balanced intake of ALA, LA, EPA, and DHA is necessary. Incorporating diverse EFA-rich foods supports optimal health and helps prevent imbalances.

Potential Health Implications

A high omega-6 to omega-3 ratio, common in modern diets, contributes to chronic inflammation, linked to diseases like cardiovascular disease and diabetes. Increasing omega-3 intake, especially from marine sources, and reducing omega-6 can promote a less inflammatory state, positively impacting health over time.

Final Thoughts on Dietary Strategy

Focusing on whole, unprocessed foods naturally provides a better balance of EFAs. Choosing fatty fish, flaxseeds, and walnuts over processed foods high in corn or sunflower oil is a practical approach. While supplements can help, especially for those with low fish intake, prioritizing whole food sources is generally best for a diverse nutrient intake. Consult a healthcare provider before starting supplements.

Frequently Asked Questions

The main difference is the body's ability to synthesize them. Essential fatty acids, like omega-3 and omega-6, cannot be made by the body and must be obtained from food. Non-essential fatty acids can be synthesized internally from other nutrients.

The two main types are alpha-linolenic acid (ALA), which is an omega-3 fatty acid, and linoleic acid (LA), which is an omega-6 fatty acid.

Humans lack the specific enzymes, particularly delta-12 and delta-15 desaturases, required to insert double bonds at the correct locations in the fatty acid carbon chain to produce ALA and LA.

Excellent sources include fatty fish like salmon, mackerel, and sardines, as well as plant-based options such as flaxseed, chia seeds, and walnuts.

Common sources include vegetable oils like sunflower, corn, and soybean oil, along with nuts such as walnuts and almonds.

Yes, maintaining a healthy balance is very important. An imbalance, particularly a high ratio of omega-6 to omega-3, can promote inflammation in the body.

Although rare with a balanced diet, essential fatty acid deficiency can lead to symptoms such as dry, scaly skin (dermatitis), increased susceptibility to infection, and impaired wound healing.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.