Understanding the Science of MSG
Monosodium glutamate, or MSG, is the sodium salt of glutamic acid, a naturally occurring amino acid found in many foods. Your body produces glutamate, and it also absorbs it from food, metabolizing both sources in the same way. The savory, or umami, flavor associated with MSG is one of the five basic tastes.
MSG was first isolated from seaweed broth in 1908 by a Japanese professor. Today, it is produced through the fermentation of starches, sugar cane, or sugar beets, a process similar to making yogurt or wine. It is used as a flavor enhancer in a wide range of foods, from processed snacks to restaurant dishes.
Setting the Acceptable Daily Intake (ADI)
For most food additives, regulatory bodies establish an Acceptable Daily Intake (ADI) to ensure consumer safety. In the case of MSG, its widespread natural occurrence and the body's efficient metabolism led some organizations, like the Joint FAO/WHO Expert Committee on Food Additives (JECFA), to place it in the safest category, “ADI not specified”. This means there is no numerical upper limit deemed necessary because dietary exposure does not pose a health hazard.
The European Food Safety Authority (EFSA), however, has established a group ADI of 30 mg per kg of body weight per day for all glutamate additives. This means a 70 kg (154 lb) person could safely consume up to 2,100 mg (2.1 grams) daily without adverse effects. This is a high threshold compared to the average intake.
A Quantitative Look at MSG Consumption
Most people consume far less MSG than the levels deemed safe by regulatory bodies. The average daily intake varies depending on diet, but is significantly below the ADI in many regions.
| Region/Source | Average Daily Intake | Context | 
|---|---|---|
| United States/UK | ~0.55 grams/day | From added and naturally occurring sources | 
| Asian Countries | 1.2–1.7 grams/day | Higher dietary exposure | 
| Typical Added Serving | Less than 0.5 grams | Per serving of an MSG-enriched food | 
| Sensitivity Threshold | > 3 grams | Consumed without food in one sitting | 
| EFSA ADI (70kg person) | 2.1 grams/day | Acceptable Daily Intake | 
Unpacking the Myth of MSG Sensitivity
The negative reputation of MSG largely stems from the controversial and poorly documented 'Chinese Restaurant Syndrome' reports from the 1960s, a narrative now widely recognized as scientifically unfounded and fueled by xenophobic biases. Scientific studies have consistently failed to demonstrate a consistent link between MSG and the reported symptoms in the general population.
Symptoms of MSG Sensitivity
While MSG is safe for the vast majority, a very small percentage of the population (less than 1%) may have a sensitivity or intolerance to it. It is not a true allergy involving an immune response but an intolerance, and symptoms are typically mild and temporary. For sensitive individuals, reactions may occur within a couple of hours after ingesting a large amount (typically 3 grams or more) on an empty stomach.
Common symptoms include:
- Headaches
- Flushing or sweating
- Numbness, tingling, or burning sensations
- Facial pressure or tightness
- Heart palpitations
- General weakness or drowsiness
- Nausea
The Importance of Context
It's important to consider context when symptoms arise. MSG is often found in highly processed foods that are also high in sodium, fats, and other additives. It is possible that these other components are the true culprits for any discomfort felt after eating. If you suspect MSG sensitivity, keeping a food diary can help identify triggers, and consulting a healthcare provider is recommended to rule out other causes.
Potential Benefits of Using MSG
Interestingly, MSG may offer benefits in certain dietary contexts. It contains significantly less sodium than table salt (sodium chloride). Using MSG to enhance the savory flavor of foods can help reduce the overall sodium content of a meal without sacrificing taste, which can be beneficial for individuals monitoring their sodium intake, such as those with high blood pressure.
Conclusion: How Much MSG Is Too Much in a Day?
Based on decades of scientific research and review by major global health authorities, how much MSG is too much in a day for most people is far more than what is typically consumed. For the general population, MSG is safe when consumed in moderation as part of a balanced diet. The stigma associated with it is largely baseless, and regulatory bodies have set very high acceptable intake levels. While a small subset may experience sensitivity, the symptoms are generally mild, temporary, and only occur with very large doses. Instead of demonizing a single ingredient, a balanced perspective should focus on overall dietary choices, emphasizing whole, unprocessed foods while enjoying flavor enhancers like MSG responsibly.
Learn more about MSG safety from authoritative sources like the U.S. Food and Drug Administration (FDA).