A high red blood cell count, or erythrocytosis, is a medical condition where your body produces an excess number of red blood cells. This can cause your blood to thicken, which slows blood flow and increases the risk of serious complications like blood clots, heart attacks, and strokes. A high RBC count may be discovered during routine blood work, and it is crucial to consult a healthcare provider for proper diagnosis and treatment. The approach to lowering RBCs depends on the underlying cause, but effective strategies often include medical treatments combined with lifestyle changes.
Medical Treatments to Reduce Red Blood Cells
For cases where lifestyle changes are insufficient or the condition is caused by an underlying disease, medical intervention is necessary. These treatments are performed under the supervision of a hematologist, a specialist in blood disorders.
Therapeutic Phlebotomy
This is one of the quickest and most common methods for reducing red blood cell count, particularly for conditions like polycythemia vera. The procedure is similar to blood donation, where a pint (about 500ml) of blood is withdrawn from a vein.
- How it works: By physically removing blood, the total volume of red blood cells in the body is immediately reduced, lowering the blood's thickness and mitigating the risk of clots.
- Frequency: Initially, phlebotomy may be required weekly until the RBC count is within a target range. The frequency is then reduced for long-term maintenance.
Medications
In some cases, especially with polycythemia vera, medications may be prescribed to control red blood cell production in the bone marrow.
- Hydroxyurea: This oral medication can slow the production of red blood cells. It requires regular monitoring by a doctor to ensure levels do not drop too low.
- Ruxolitinib: This drug is used for certain types of erythrocytosis that involve a specific genetic mutation, like JAK2, and can be an option if other treatments are ineffective.
- Interferon alpha: Administered by injection, this medication can help suppress the overproduction of blood cells.
Lifestyle and Dietary Adjustments
For less severe cases, or as a complement to medical treatments, certain lifestyle and dietary changes can help manage and reduce RBC counts.
Key Lifestyle Modifications
- Quit Smoking: Smoking reduces oxygen levels in the blood, prompting the body to produce more red blood cells to compensate. Quitting can help normalize oxygenation and RBC production.
- Stay Hydrated: Dehydration can cause a false high in RBC count, a condition known as relative erythrocytosis, because blood plasma volume is reduced. Drinking plenty of water can help normalize blood volume.
- Moderate Exercise: Regular, moderate-intensity exercise improves circulation and oxygen efficiency, but extreme endurance sports can sometimes temporarily increase RBCs.
- Avoid High Altitudes: Living or spending significant time at high altitudes can trigger increased RBC production due to lower oxygen availability. Avoiding these areas can help regulate levels.
- Limit Alcohol: Excessive alcohol can contribute to dehydration and other issues that can influence blood cell concentration.
Dietary Considerations
- Limit Iron-Rich Foods: Since iron is a key component of red blood cells, excessive intake can stimulate production. Reducing consumption of foods high in iron, such as red meat and fortified cereals, can be beneficial.
- Increase Antioxidant Intake: Including foods rich in antioxidants, like fruits and leafy greens, may help reduce oxidative stress, which can play a role in abnormal RBC production.
- Choose Lean Proteins: Opt for lean protein sources like fish and poultry instead of excessive red and organ meats.
Medical Intervention vs. Lifestyle Changes
| Feature | Medical Intervention (Phlebotomy/Medication) | Lifestyle Changes (Diet/Hydration) | 
|---|---|---|
| Speed of Effect | Can provide a rapid decrease in RBC count, especially phlebotomy. | Effects are gradual and require consistent, long-term adherence. | 
| Suitability | Best for severe or chronic conditions like polycythemia vera. | Best for mild cases, relative erythrocytosis, and supporting medical treatment. | 
| Underlying Cause | Directly addresses the overproduction of cells in primary conditions. | Primarily addresses contributing factors like dehydration or smoking. | 
| Professional Oversight | Requires ongoing monitoring and management by a hematologist. | Should be guided by a doctor's recommendations following a diagnosis. | 
| Side Effects | Potential side effects from medication; risk of infection from procedures. | Generally low risk, focuses on promoting overall health. | 
Conclusion
Effectively reducing a high red blood cell count requires a clear understanding of its underlying cause, which can range from benign issues like dehydration to serious conditions like polycythemia vera. The most rapid and direct treatments involve medical procedures such as therapeutic phlebotomy and prescription medications that target bone marrow production. However, long-term management and support for these treatments often depend on sustainable lifestyle changes, including staying hydrated, quitting smoking, and adjusting dietary iron intake. As always, consulting a healthcare professional is the essential first step to determine the right course of action and ensure safety.
For more in-depth information on blood disorders and treatment options, consult the Mayo Clinic's detailed guide on polycythemia vera, a specific cause of high red blood cell count: https://www.mayoclinic.org/diseases-conditions/polycythemia-vera/diagnosis-treatment/drc-20355855.