The simple and direct answer is yes, traditionally, hydrolyzed collagen is made from animals. Collagen is a protein found exclusively in animal connective tissues, and the supplements are derived from these animal byproducts. For those following a vegetarian or vegan lifestyle, this distinction is crucial when choosing supplements. Understanding the source, the manufacturing process, and the differences between traditional and newer alternatives helps consumers make informed decisions.
The Traditional Production Process
Hydrolyzed collagen, also known as collagen peptides, is produced by breaking down the raw collagen into smaller protein fragments. This process is called hydrolysis and typically involves several steps:
- Sourcing Raw Materials: The process begins with collecting animal byproducts, such as the hides, bones, and cartilage of cows, pigs, or fish. These are often by-products of the meat and fishing industries, making them an efficient use of resources.
- Cleaning and Preparation: The raw materials are thoroughly cleaned to remove impurities before processing.
- Hydrolysis: This is the core step where the large, native collagen molecules are broken down. Manufacturers commonly use enzymes (enzymatic hydrolysis) or chemical agents (acid or alkaline hydrolysis) to cleave the peptide bonds. Enzymatic hydrolysis is a popular method due to its precision and control over the final peptide size.
- Purification and Drying: The resulting collagen peptides are then filtered and purified to remove any remaining contaminants. The liquid is then dried into a powder, making it soluble and easy to digest.
Primary Animal Sources of Hydrolyzed Collagen
Different animal sources provide different types of collagen, which are used to target specific health goals.
- Bovine Collagen: Sourced from the hides and bones of cows. It is rich in Type I and Type III collagen, which are beneficial for skin, bone, and gut health.
- Marine Collagen: Sourced from fish skin, scales, and bones, often from wild-caught or farmed fish. It is primarily composed of Type I collagen, which is great for skin, hair, and nail health. It is also pescetarian-friendly and can be a choice for those with religious restrictions on pork and beef.
- Porcine Collagen: Derived from the skin and bones of pigs. It provides Types I and III collagen, similar to bovine collagen.
- Poultry Collagen: Extracted from chicken cartilage and bones. It is a rich source of Type II collagen, which is beneficial for supporting joint health and cartilage.
Understanding the “Vegan Collagen” Misconception
For ethical and dietary reasons, many people seek a plant-based alternative. However, the term “vegan collagen” is fundamentally a marketing term, as plants do not naturally produce collagen. Instead, vegan supplements take one of two main approaches:
- 
Collagen Boosters: These products contain the amino acids and co-factors necessary for the body to produce its own collagen. They provide the raw building blocks rather than the pre-formed peptides found in animal sources. Key ingredients often include: - Amino Acids: Glycine, proline, and lysine, which are the main components of collagen.
- Vitamin C: Crucial for collagen synthesis and stability.
- Zinc and Copper: Minerals that play a vital role in the body's collagen production process.
- Silica: A mineral found in bamboo and horsetail extracts that supports collagen synthesis.
 
- 
Bio-Engineered Collagen: Through advancements in biotechnology, scientists can genetically modify yeast or bacteria to produce collagen-like peptides. These are fermented and then purified to create a product that mimics the structure and function of animal collagen. This is a true non-animal protein source, though still relatively new and less common than boosters. 
Comparison: Animal-Sourced vs. Vegan Alternatives
| Feature | Animal-Sourced Hydrolyzed Collagen | Vegan Collagen Boosters | Bio-Engineered Vegan Collagen | 
|---|---|---|---|
| Source | Animal by-products (hides, bones, scales, etc.) | Plant-based ingredients and amino acids | Genetically modified yeast and bacteria | 
| Composition | Pre-formed collagen peptides (short amino acid chains) | Amino acids and nutrients needed for the body to synthesize its own collagen | Lab-produced collagen-like peptides | 
| Availability | Widely available and common in the market | Very common as supplements and powders | Limited availability, emerging in the market | 
| Bioavailability | High; peptides are easily absorbed by the body | Indirect; depends on the body's ability to use the provided building blocks | Expected to have high bioavailability due to controlled production | 
| Ethical/Dietary | Not suitable for vegans or vegetarians; depends on animal source | Suitable for all plant-based diets | Suitable for plant-based diets; ethical implications may be debated by some | 
| Primary Use | Supplementing for skin, joint, bone, and gut health | Boosting the body's natural synthesis of collagen | Functional ingredient aiming to replicate animal collagen's effects | 
Conclusion
While the market for collagen supplements continues to grow, it is clear that traditional hydrolyzed collagen is unequivocally derived from animal sources. The most common types come from cows and fish, which provide different collagen types for specific applications. For those committed to a plant-based diet, understanding that true collagen is an animal protein is the first step. The good news is that alternatives exist, ranging from supplements that provide the necessary building blocks to more modern, bio-engineered versions that replicate collagen function. By carefully checking the source, manufacturing method, and ingredients, consumers can choose a supplement that aligns with their dietary needs and ethical values.
Harvard T.H. Chan School of Public Health: Collagen
What is the difference between undenatured and hydrolyzed collagen?
Undenatured vs. Hydrolyzed: Undenatured collagen is the native, triple-helix protein that has not been broken down, while hydrolyzed collagen (peptides) has been processed into smaller, more easily absorbed fragments.
How does the hydrolysis process make collagen more beneficial?
Enhanced Absorption: The hydrolysis process breaks the large collagen molecules into small peptides, which significantly increases their bioavailability, making them easier for the body to digest and absorb effectively.
Is bovine collagen suitable for pescetarians?
Pescetarian suitability: No, bovine collagen comes from cows and is not suitable for a pescetarian diet, which allows for fish but excludes meat from land animals like cattle.
Can a vegan diet provide enough building blocks for collagen production?
Vegan Diet for Collagen: A well-planned vegan diet, rich in amino acids from legumes, seeds, and nuts, along with key nutrients like Vitamin C, can provide the body with the resources it needs to synthesize its own collagen.
What are some examples of vegan collagen booster ingredients?
Booster Ingredients: Vegan boosters typically contain a blend of amino acids (glycine, proline, lysine) derived from fermented sources, along with vitamins and minerals like Vitamin C, zinc, and silica.
Is eggshell membrane a vegan source of collagen?
Eggshell membrane: No, collagen from eggshell membranes is a vegetarian source, not a vegan one, as it comes from a hen's egg.
Why is checking the source important for those with allergies?
Allergen Avoidance: Because hydrolyzed collagen is derived from animals like fish, beef, or poultry, individuals with allergies to those sources should avoid the corresponding collagen supplements to prevent allergic reactions.