Skip to content

Is magnesium glycinate better absorbed than magnesium citrate?

4 min read

According to the National Institutes of Health, a significant portion of the population doesn't meet the recommended daily intake of magnesium. This has led to a boom in magnesium supplements, but a crucial question for many is: is magnesium glycinate better absorbed than magnesium citrate?

Quick Summary

A comparison of the bioavailability, intended purpose, and side effects of magnesium glycinate versus magnesium citrate. This guide clarifies which form might be more suitable for your specific health objectives, whether for relaxation or digestive support.

Key Points

  • Superior Bioavailability: Magnesium glycinate is a highly bioavailable form of magnesium, meaning it is absorbed more efficiently and effectively by the body.

  • Minimal Digestive Impact: Unlike magnesium citrate, magnesium glycinate is very gentle on the stomach and does not cause a laxative effect.

  • Calming Benefits: The glycine in magnesium glycinate promotes relaxation and can improve sleep quality and reduce anxiety.

  • Constipation Relief: Magnesium citrate's primary use is as an osmotic laxative to relieve occasional constipation.

  • Purpose Dictates Choice: Choose magnesium glycinate for daily supplementation and calming effects, and magnesium citrate for short-term digestive relief.

  • Higher Doses, Higher Risk: Higher doses of magnesium citrate are more likely to cause significant digestive upset, including diarrhea.

In This Article

When it comes to supplementing with magnesium, the sheer variety of options on the market can be overwhelming. Beyond just the dosage, the form of magnesium—what it's chemically bound to—can dramatically affect its bioavailability, or how efficiently your body absorbs and uses the mineral. Magnesium glycinate and magnesium citrate are two of the most popular forms, but they serve different purposes due to their distinct characteristics.

Understanding Bioavailability and Chemical Form

Bioavailability is a key consideration when choosing any supplement. A supplement with high bioavailability means a greater percentage of the nutrient is absorbed and utilized by the body, leading to more effective supplementation. Both magnesium glycinate and citrate are organic forms of magnesium, which are generally better absorbed by the body than inorganic forms like magnesium oxide. The real difference lies in the compounds they are chelated with and how those compounds influence absorption and overall effect.

Magnesium Glycinate: High Absorption and Gentle on the Stomach

Magnesium glycinate is formed by combining elemental magnesium with the amino acid glycine. This chelation process creates a stable compound that is highly bioavailable and easily absorbed in the small intestine. The presence of glycine also contributes to its benefits:

  • Superior Tolerability: Unlike many other forms, magnesium glycinate rarely causes gastrointestinal discomfort, such as diarrhea, because it does not act as an osmotic laxative. This makes it ideal for long-term daily supplementation, especially for those with sensitive digestive systems.
  • Calming and Relaxation Effects: Glycine itself is a calming neurotransmitter. This synergistic effect makes magnesium glycinate particularly effective for promoting relaxation, reducing stress and anxiety, and improving sleep quality.
  • Muscle Relaxation: Its high absorption rate makes it effective for alleviating muscle cramps and promoting general muscle relaxation.
  • Supports Neurological Health: The combination of magnesium and glycine supports healthy nerve function and neurological processes, enhancing cognitive function and focus.

Magnesium Citrate: Good Absorption with a Laxative Effect

Magnesium citrate is a combination of magnesium and citric acid. While it is also well-absorbed by the body, it has a distinct primary function that sets it apart from glycinate. Citric acid acts as a mild osmotic laxative, drawing water into the intestines. This is why magnesium citrate is frequently used for relieving occasional constipation. Its specific properties make it beneficial for:

  • Constipation Relief: As an osmotic laxative, magnesium citrate effectively promotes bowel movements, making it a go-to for clearing the intestines before medical procedures or for occasional relief.
  • Addressing Mild Deficiency: Due to its decent absorption rate, magnesium citrate can help correct a magnesium deficiency, though the potential laxative effect may not make it suitable for consistent, high-dose use.
  • Replenishing Electrolytes: It can be used to replenish magnesium lost during physical activity, particularly when combined with proper hydration.

Magnesium Glycinate vs. Citrate: A Comparative Look

The best form of magnesium for you depends heavily on your individual needs. The following table provides a quick side-by-side comparison to help you decide.

Aspect Magnesium Glycinate Magnesium Citrate
Primary Use Promoting relaxation, sleep, stress reduction, general supplementation Relieving occasional constipation, bowel preparation
Absorption Rate Very high; chelated for optimal uptake Good; generally considered high, but can be influenced by dosage
Digestive Impact Minimal; gentle on the stomach Mild to potent laxative effect; can cause diarrhea, gas, and cramping at higher doses
Key Side Effect Generally well-tolerated, rare side effects Diarrhea, abdominal cramps, nausea, especially at higher doses
Best For Daily, long-term use; individuals with sensitive digestion; sleep and anxiety support Occasional use for constipation; individuals without sensitive GI issues

Factors Influencing Your Choice

Your choice between these two forms of magnesium should be driven by your health objectives and personal sensitivity. For most people seeking daily support for stress, sleep, or overall wellness without digestive upset, magnesium glycinate is the superior choice. Its high tolerability and specific benefits for the nervous system make it a reliable, long-term option.

Conversely, if your primary goal is to address occasional constipation, magnesium citrate is highly effective and well-suited for that specific purpose. It’s not, however, recommended for ongoing, daily intake in high doses due to its laxative properties. Some individuals may even benefit from taking both strategically—using citrate for short-term digestive issues and glycinate for daily calming and sleep support. Consulting a healthcare provider can help you determine the right strategy for your body's specific needs.

Conclusion: The Right Magnesium for Your Needs

Ultimately, the question of whether is magnesium glycinate better absorbed than magnesium citrate depends on the context. Both are well-absorbed organic forms of magnesium, but their distinct properties make them suitable for different applications. For systemic absorption intended to support relaxation, sleep, and overall neurological function with minimal digestive side effects, magnesium glycinate is the winner. For specific, short-term relief of constipation, magnesium citrate is the more appropriate tool due to its potent laxative effect. By understanding these differences, you can make an informed decision and choose the magnesium supplement that best aligns with your personal health goals. For additional information on dietary supplements, you can consult authoritative resources such as the National Institutes of Health Office of Dietary Supplements.

Frequently Asked Questions

Magnesium glycinate is generally considered superior for sleep and anxiety. The glycine it is chelated with has a calming effect on the nervous system, helping to promote relaxation and improve sleep quality.

Yes, some people do take both. A common strategy is to take magnesium citrate in the morning for its digestive effects and magnesium glycinate in the evening for its calming and sleep benefits.

For consistent, long-term absorption, the laxative effect of magnesium citrate can be problematic. Increased bowel motility can reduce the time for absorption, making it less ideal than glycinate for correcting systemic deficiency.

If you have a sensitive stomach or a history of gastrointestinal issues, magnesium glycinate is the better choice. Its non-laxative nature makes it much easier to tolerate for daily use.

Pricing can vary depending on the brand and quality, but magnesium glycinate is often slightly more expensive per absorbed unit than magnesium citrate due to the more complex chelation process involved. However, its higher bioavailability can offer better value.

The time it takes to notice effects varies. Relief from constipation with magnesium citrate can be felt within hours, while benefits like improved sleep or reduced anxiety from magnesium glycinate might take days to weeks of consistent supplementation.

Yes, magnesium can interact with certain antibiotics, diuretics, and medications for osteoporosis. Always consult your healthcare provider before starting any new supplement, especially if you take other medications or have underlying health conditions.

References

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.