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Is sulfur available as a supplement? A look at MSM and its forms

5 min read

As the body's third most abundant mineral, sulfur is critical for numerous physiological processes, but many people still ask, "Is sulfur available as a supplement?". It can be found in dietary supplements, most notably in the organic compound methylsulfonylmethane, or MSM.

Quick Summary

Yes, sulfur is available in supplement form, most commonly as methylsulfonylmethane (MSM), which is promoted for joint, skin, and immune health. Deficiency is rare, as sulfur is plentiful in a protein-rich diet.

Key Points

  • MSM is the primary supplement form: Yes, sulfur is available as a supplement, most commonly as Methylsulfonylmethane (MSM).

  • Supports joint health: MSM supplements are often used to help reduce joint pain, stiffness, and inflammation associated with conditions like osteoarthritis.

  • Benefits for skin, hair, and nails: As a sulfur donor for keratin, MSM can help strengthen these tissues and may improve overall skin health.

  • Generally considered safe: Short-term use of MSM is typically well-tolerated, but some people may experience mild side effects like nausea or bloating.

  • Abundant in whole foods: Many protein-rich foods and cruciferous vegetables contain sufficient sulfur, making supplementation unnecessary for most healthy individuals.

In This Article

Understanding Sulfur's Role in the Body

Sulfur is a non-metallic element that is essential for human health, playing a crucial role in cell repair, metabolism, digestion, and growth. It is a key component of two important amino acids, methionine and cysteine, which are the building blocks of protein. These sulfur-containing amino acids are vital for producing critical molecules, including the powerful antioxidant glutathione, and for maintaining the structure of proteins in skin, hair, and nails. The body cannot produce methionine, making it an essential nutrient that must be obtained from the diet, while cysteine can be synthesized from methionine. While a balanced diet generally provides sufficient sulfur for most people, supplements offer an alternative way to boost intake, particularly in certain forms like MSM.

The Primary Sulfur Supplement: Methylsulfonylmethane (MSM)

When people seek a sulfur supplement, they are most often looking for methylsulfonylmethane, or MSM. MSM is a naturally occurring organic compound found in small amounts in some plants, animals, and humans. It is also manufactured synthetically for use in dietary supplements. MSM is valued for its high bioavailability, meaning the body can absorb and use the sulfur from it efficiently. Unlike elemental sulfur, which the body cannot readily utilize, MSM is in a form that is easily assimilated. MSM supplements are widely available in various forms, including capsules, powders, and creams, and are commonly used to target joint and skin health.

Potential Benefits of MSM

Research on MSM has explored its potential benefits for several conditions, showing promising, though sometimes mixed, results. The most commonly cited benefits are:

  • Relieves joint pain: Studies, particularly those concerning osteoarthritis of the knee, have shown that MSM may help reduce pain and stiffness and improve physical function. It has anti-inflammatory properties that can help protect cartilage.
  • Reduces inflammation: MSM is known to have anti-inflammatory effects by inhibiting the activity of inflammatory compounds and boosting levels of the antioxidant glutathione. This can help with conditions related to chronic inflammation.
  • Supports skin, hair, and nails: As a source of sulfur for keratin, MSM can help improve the strength and structure of hair, skin, and nails. Some studies also suggest it may help reduce skin redness and irritation.
  • Speeds exercise recovery: By reducing inflammation and oxidative stress after intense workouts, MSM may help reduce muscle damage and soreness, aiding in faster recovery.
  • Eases allergy symptoms: Some evidence suggests MSM can help reduce symptoms of allergic rhinitis, such as congestion and sneezing, by lowering inflammation.
  • Boosts immune function: Sulfur is important for immune health, and MSM's ability to combat oxidative stress and increase glutathione levels can help support the immune system.

Safety and Side Effects

MSM supplements are generally considered safe for most people when used short-term and within recommended dosages. The FDA has given MSM the "Generally Recognized As Safe" (GRAS) designation. Potential side effects are usually mild and may include:

  • Nausea
  • Bloating
  • Diarrhea
  • Stomach discomfort
  • Headaches

Note: Long-term safety is not yet fully understood, and the use of MSM by pregnant or breastfeeding individuals is not recommended due to a lack of sufficient research. It is always best to consult a healthcare provider before beginning any new supplement regime.

Comparison: MSM vs. Other Sulfur Forms

It's important to understand the difference between the commonly available supplement MSM and other forms of sulfur.

Feature Methylsulfonylmethane (MSM) Dimethyl Sulfoxide (DMSO) Elemental Sulfur Sulfates (e.g., Glucosamine Sulfate)
Availability Available as an oral dietary supplement (capsules, powder) and topical creams. Primarily used topically as a solvent and carrier for other substances. Administered by healthcare professionals for specific conditions. Pure, inorganic form, not bioavailable for internal human consumption. Sometimes included in joint health supplements alongside MSM.
Use Supports joint, skin, hair, and immune health. Anti-inflammatory properties. Used to relieve pain and inflammation when applied to the skin. FDA-approved for specific medical procedures. Historically used in industrial applications, agriculture, and externally in some skin preparations. Used for joint pain, often in combination with MSM.
Bioavailability High; easily absorbed and utilized by the body. Rapidly absorbed through the skin due to its penetrating properties. Poor for internal consumption; the body immediately rejects it. Bioavailability depends on the specific compound; generally absorbed differently than organic MSM.
Safety Generally considered safe for short-term oral use with mild potential side effects. Requires professional administration for internal use; topical application can cause skin irritation. Considered potentially toxic if ingested internally. Generally safe when used as directed in supplements.

Natural Sources of Sulfur

For most people, sufficient sulfur is obtained through diet, especially from protein-rich foods. Excellent dietary sources include:

  • Allium Vegetables: Garlic, onions, and leeks are rich in organic sulfur compounds.
  • Cruciferous Vegetables: Broccoli, cauliflower, Brussels sprouts, and kale contain sulfur in the form of glucosinolates.
  • Animal-Based Proteins: Eggs, fish, poultry, and beef are rich in the sulfur-containing amino acids methionine and cysteine.
  • Legumes: Lentils, chickpeas, and beans are good plant-based sources of sulfur.
  • Whole Grains: Some whole grains contain sulfur in the form of vitamins like thiamin.

How a Sulfur Supplement is Used

Sulfur supplements, specifically MSM, are available in various forms and dosages. They can be found in capsules, tablets, or powder form for oral consumption. Topical gels and creams are also available for external application to the skin and joints. Some supplements combine MSM with other ingredients like glucosamine and chondroitin, particularly those targeting joint health. Dosage recommendations for MSM typically range from 500 to 3,000 mg per day, though there is no official recommended daily allowance for sulfur itself. It is important to start with a lower dose and gradually increase it, monitoring for any side effects. As with any supplement, consulting a healthcare professional is wise to ensure it is appropriate for your individual needs.

Conclusion: Making an Informed Choice

Yes, sulfur is widely available as a supplement, primarily in the form of Methylsulfonylmethane (MSM), which is generally considered safe for short-term use and offers potential benefits for joint health, skin, and more. However, elemental sulfur is not a viable dietary supplement, and a healthy, balanced diet is typically sufficient to meet the body's sulfur needs. While research on MSM is promising for several uses, it's not a cure-all, and results can be mixed. Before adding a sulfur supplement to your regimen, especially if you have an underlying health condition or are pregnant, consult with a healthcare provider to ensure it's the right choice for you. For many, focusing on a diet rich in sulfur-containing foods remains the most beneficial and safest approach.

For more detailed information on MSM, refer to scientific databases such as the National Institutes of Health's PubMed Central, where relevant studies are often indexed, such as this review on MSM's applications and safety: Methylsulfonylmethane: Applications and safety of a novel dietary supplement.

Frequently Asked Questions

No, there is no official recommended dietary allowance (RDA) for sulfur. Most people are able to obtain sufficient amounts through a balanced diet, especially one rich in protein.

MSM (Methylsulfonylmethane) is a specific, organic, and bioavailable compound that contains sulfur and is used in supplements. Elemental sulfur, in its raw form, is not effectively absorbed by the body.

Excellent food sources of sulfur include eggs, fish, beef, poultry, legumes, and allium vegetables like garlic, onions, and leeks. Cruciferous vegetables such as broccoli and cauliflower are also high in sulfur.

MSM contributes sulfur to keratin, the protein that makes up hair, potentially strengthening it. While some studies suggest benefits, more research is needed to definitively confirm its effectiveness for hair growth.

A true sulfur deficiency is considered rare, as the mineral is widely available in protein-rich foods. Individuals on low-protein diets, like some vegetarians, may have lower intake.

Common, mild side effects of MSM can include gastrointestinal discomfort such as nausea, bloating, and diarrhea. Headaches have also been reported in some cases.

Yes, an allergy to sulfa-based drugs does not mean you will have a similar reaction to the organic sulfur in MSM. They are not chemically related, and there is no documented crossover reaction.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.