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Regular Magnesium vs. Magnesium Glycinate: Which is Better?

4 min read

According to the National Institutes of Health, nearly half of the population in the United States does not consume enough magnesium through their diet, making supplementation a common practice. Deciding which supplement to take can be confusing, so it is important to know the difference between regular magnesium vs. magnesium glycinate to choose the right one for your body.

Quick Summary

This guide compares different forms of magnesium supplements, focusing on the key differences between regular (often inorganic) forms and magnesium glycinate. It covers bioavailability, digestive impact, and specific health benefits to help you decide which is more suitable for your needs.

Key Points

  • Superior Bioavailability: Magnesium glycinate is significantly better absorbed by the body compared to 'regular' forms like magnesium oxide.

  • Gentle on Digestion: Magnesium glycinate is far less likely to cause digestive upset, diarrhea, or cramping, making it ideal for sensitive stomachs.

  • Relaxation and Sleep Support: The glycine in magnesium glycinate has calming properties, making this form highly effective for reducing anxiety and improving sleep quality.

  • Constipation Relief: 'Regular' magnesium, most often magnesium oxide, is primarily effective as a laxative due to its low absorption rate.

  • Long-term vs. Short-term Use: Magnesium glycinate is the better choice for consistent, long-term supplementation to address deficiencies, while magnesium oxide is suited only for short-term digestive relief.

  • Cost vs. Value: While magnesium oxide is cheaper upfront, its low absorption rate means it offers less value for systemic health benefits compared to the more bioavailable magnesium glycinate.

In This Article

Disclaimer: This information is for general knowledge and should not be taken as medical advice. Consult with a healthcare professional before starting any new supplement regimen.

Understanding the Magnesium Spectrum

Before pitting regular magnesium against magnesium glycinate, it is crucial to understand that "regular" often refers to cheaper, inorganic forms like magnesium oxide. In contrast, magnesium glycinate is a chelated, or bound, form of magnesium with a distinct absorption profile and set of benefits. The key to choosing is not just considering the label, but understanding what your body does with the supplement once you take it. Your health goals—be they better sleep, reduced anxiety, or constipation relief—should directly influence your decision.

What is Magnesium Glycinate?

Magnesium glycinate is formed by binding elemental magnesium to the amino acid glycine. This chelation process is the secret to its high bioavailability and gentle nature. The body can absorb this form more efficiently and with far less digestive distress compared to inorganic alternatives. The presence of glycine also lends additional benefits, as glycine itself is known for its calming properties. This makes it an ideal choice for those seeking to reduce anxiety, improve sleep quality, and alleviate muscle tension.

What is "Regular" Magnesium?

For many consumers, the term "regular magnesium" refers to the most common and inexpensive form: magnesium oxide. While it contains a high concentration of elemental magnesium by weight, its solubility and, therefore, its bioavailability are extremely low. A significant portion of ingested magnesium oxide is not absorbed and instead passes through the digestive system, where it can exert a laxative effect. For this reason, it is more commonly used as a short-term treatment for constipation or heartburn rather than a daily supplement for addressing a magnesium deficiency.

Bioavailability: The Ultimate Deciding Factor

The most significant difference between these two types of magnesium is their bioavailability—the rate and extent to which the body can absorb and utilize the mineral. This factor is where magnesium glycinate truly shines.

  • Magnesium Glycinate: Due to its chelated structure, it is highly bioavailable, with absorption rates shown to be superior to inorganic salts. The body recognizes and absorbs the magnesium-glycine compound efficiently, making it an effective choice for correcting a magnesium deficiency and delivering systemic benefits.
  • Magnesium Oxide: This form has notoriously poor bioavailability, with some studies showing absorption as low as 4%. The low absorption rate means that for systemic benefits, a large portion of the supplement is wasted and can cause unwanted side effects.

Comparison of Magnesium Supplements

Feature Magnesium Glycinate Magnesium Oxide (Regular) Magnesium Citrate Magnesium Malate
Primary Benefit Relaxation, anxiety relief, improved sleep Constipation relief, antacid Mild laxative, energy metabolism Energy production, muscle recovery
Bioavailability High; very well-absorbed Very low; poorly absorbed Moderate-High; better than oxide High; well-absorbed
Digestive Impact Gentle; less likely to cause diarrhea Can cause diarrhea and GI upset Laxative effect, can cause diarrhea Gentle; well-tolerated
Recommended Use Long-term daily supplementation Short-term constipation or heartburn Occasional constipation, general support Chronic pain, fatigue
Special Feature Calming effect from glycine High elemental magnesium content Can help prevent kidney stones Contains malic acid for energy

How to Choose the Right Supplement for You

Your health goals are the most important factor when choosing a magnesium supplement. If you are aiming to improve your sleep, reduce anxiety, or correct a long-term deficiency, magnesium glycinate is the superior choice due to its high bioavailability and gentle effects. The calming properties of glycine are an added bonus. However, if your primary and occasional need is for a laxative or antacid, the lower-cost magnesium oxide or citrate may be effective for short-term use.

For those with sensitive stomachs, magnesium glycinate is the clear winner as it is far less likely to cause digestive upset than magnesium oxide or citrate. It provides systemic benefits without the uncomfortable side effects, making it better for consistent, daily use.

Conclusion

When weighing what is better, regular magnesium or magnesium glycinate, the answer depends on your specific health objectives. For addressing a magnesium deficiency, supporting mental health, and promoting restful sleep, magnesium glycinate is the superior option due to its significantly higher bioavailability and gentler effect on the digestive system. The glycine component provides added benefits for relaxation. In contrast, "regular" magnesium, typically magnesium oxide, has poor absorption and is better suited for its laxative properties or for short-term digestive issues. Ultimately, for long-term health benefits, magnesium glycinate offers a more effective and tolerable path to increasing your magnesium levels.

Disclaimer: Consult with a healthcare provider before starting any new supplement regimen to ensure it aligns with your individual health needs.

Magnesium Fact Sheet for Health Professionals from the National Institutes of Health offers a deeper dive into magnesium's role and daily requirements.

Frequently Asked Questions

Yes, magnesium glycinate is considered one of the most bioavailable and absorbable forms of magnesium due to its chelated nature, which enhances its uptake by the body.

Magnesium oxide is not recommended for long-term magnesium deficiency due to its poor absorption rate. Most of the supplement passes through the body unabsorbed, making it ineffective for raising systemic magnesium levels.

Magnesium glycinate is typically recommended for anxiety because the amino acid glycine has calming effects that help reduce stress and promote relaxation.

Yes, magnesium glycinate is well-known for its ability to improve sleep quality. The combination of magnesium, which helps regulate neurotransmitters, and glycine, which promotes relaxation, can help you fall asleep faster and achieve deeper rest.

While both are more absorbable than magnesium oxide, magnesium glycinate is favored for its calming effects and gentleness on the stomach. Magnesium citrate is known for its mild laxative effect and is often used to relieve constipation.

Yes, magnesium glycinate is one of the gentlest forms of magnesium on the digestive system. It is less likely to cause the common gastrointestinal side effects, such as diarrhea, that are associated with other forms.

Determining the correct dosage for sleep or anxiety relief should be done in consultation with a healthcare provider. They can provide personalized recommendations based on your individual needs and health status.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.