How many calories are in 22 grapes? The complete nutritional facts
                                
                                
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                                    4 min read                                
                            
                                A 100-gram serving of grapes contains approximately 69 calories, but for a specific portion of 22 medium-sized grapes, the total is closer to 75 to 85 calories, depending on their size and variety. This makes them a sweet and hydrating low-calorie snack option for any time of day.