What is Protein Biological Value?
The biological value (BV) of a protein is a metric that measures the proportion of protein absorbed from a food that gets incorporated into the body's own proteins. It essentially indicates how efficiently the body can utilize a given protein source for growth and repair. This value is largely determined by the protein's amino acid profile, specifically the presence and balance of the nine essential amino acids (EAAs). Our bodies cannot produce EAAs, so we must obtain them through our diet. A protein source that provides all nine EAAs in sufficient quantities is considered a 'complete' protein, while one that is deficient in one or more is called an 'incomplete' protein.
The concept of BV helps explain why protein sources differ in their nutritional quality, even if they have the same total protein content. Higher BV indicates that the amino acids are in proportions highly compatible with the body's needs, leading to greater nitrogen retention and less waste. In contrast, lower BV means a smaller percentage of the absorbed nitrogen is retained for tissue synthesis, with a higher proportion excreted.
High Biological Value (HBV) Proteins
High biological value proteins contain all the essential amino acids in the right proportions for human nutrition. This means the body can use them effectively to build and repair tissues. The most common sources of HBV proteins are animal-based, although some plant foods also qualify.
Common High Biological Value Protein Sources:
- Eggs: Often cited as the gold standard for protein quality, eggs are a complete protein source with high bioavailability.
- Meat, Poultry, and Fish: These animal proteins provide a complete profile of essential amino acids and are highly digestible.
- Dairy Products: Milk, cheese, and yogurt are all excellent sources of HBV protein. Whey protein, a dairy derivative, is particularly bioavailable and popular among athletes.
- Soy and Soy Products: Soybeans are a rare plant-based source of complete protein. Products like tofu, tempeh, and edamame are excellent options for vegans and vegetarians.
- Quinoa: This ancient grain is another notable plant-based complete protein, offering all nine EAAs.
Low Biological Value (LBV) Proteins
Low biological value proteins are deficient in one or more of the essential amino acids, limiting the body's ability to synthesize new proteins. Most plant-based proteins fall into this category. The limiting amino acid varies by food type; for example, most legumes are low in methionine, while many grains are low in lysine.
Common Low Biological Value Protein Sources:
- Legumes: Beans, peas, and lentils are typically low in the sulfur-containing amino acid methionine.
- Grains: Wheat, rice, and oats often lack sufficient lysine.
- Nuts and Seeds: Many nuts and seeds are low in lysine or threonine.
- Gelatin: A protein derived from animal collagen, gelatin is deficient in tryptophan and several other EAAs, giving it an extremely low BV.
Complementary Proteins for a Complete Amino Acid Profile
For those relying on plant-based diets, a strategy known as protein complementation ensures all essential amino acids are consumed. This involves combining different LBV protein sources, either in the same meal or over the course of a day, to provide a complete amino acid profile. The liver can store a pool of essential amino acids for a period of time, meaning you don't need to combine complementary proteins in a single meal to reap the benefits.
Classic examples of complementary protein pairings:
- Grains and Legumes: Rice and beans, or tortillas with refried beans, are classic combinations where the lysine-rich beans complement the methionine-rich rice.
- Seeds and Legumes: Hummus, made from chickpeas and sesame seed tahini, creates a complete protein.
- Nuts and Grains: Peanut butter on whole wheat bread is a simple example.
Variety is the key to a healthy vegan or vegetarian diet, as consuming a wide range of plant foods will naturally lead to a complete amino acid intake over the day.
Bioavailability and Other Factors Affecting Protein Quality
Beyond the amino acid profile, other factors influence how effectively the body uses protein. Digestibility and bioavailability are key considerations. For instance, a protein with high digestibility is easily broken down into its constituent amino acids and absorbed. Plant proteins can be less bioavailable than animal proteins because their fibrous plant walls can interfere with digestion. However, cooking and processing methods can affect digestibility, sometimes for the better, as seen with legumes. Other nutrients in a meal and even an individual's metabolic state (e.g., age, physical activity level) can influence how protein is utilized.
A Comparison of High and Low Biological Value Protein
| Feature | High Biological Value (HBV) Protein | Low Biological Value (LBV) Protein | 
|---|---|---|
| Essential Amino Acids | Contains all nine EAAs in sufficient amounts. | Deficient in one or more EAAs. | 
| Common Sources | Meat, eggs, dairy, soy, quinoa. | Grains (except quinoa), legumes (except soy), most nuts, seeds. | 
| Animal vs. Plant | Primarily from animal sources, with exceptions like soy and quinoa. | Primarily from plant sources. | 
| Digestibility | Generally higher digestibility and bioavailability. | Can have lower digestibility due to fiber and other compounds. | 
| Usage by Body | More efficiently used for protein synthesis and nitrogen retention. | Less efficiently used, requires combining for optimal synthesis. | 
| Examples | Chicken breast, salmon, whey protein, whole eggs. | Beans, lentils, bread, pasta, most cereals. | 
Conclusion
Understanding the biological value of protein is a cornerstone of modern nutritional science, helping us make informed dietary choices. High biological value proteins, typically from animal sources and a few plant-based foods, provide a complete set of essential amino acids for efficient bodily function. Low biological value proteins, mainly found in plants, require strategic combining to achieve a complete amino acid profile. A varied and balanced diet that includes a mix of protein sources is the most practical way for most individuals to ensure they meet their daily protein needs and support overall health. Whether you are an omnivore, vegetarian, or vegan, prioritizing a diverse intake of protein-rich foods is the most effective approach to optimal nutrition. For more information on protein quality, consider visiting the National Institutes of Health (NIH) website for reliable research and recommendations.