The Crucial Role of Vitamin K in Coagulation
Vitamin K is the essential nutrient for blood clotting. It is a group of fat-soluble vitamins with two main forms: K1 (phylloquinone) from plants and K2 (menaquinone) from animal products and gut bacteria. The liver needs vitamin K to produce clotting factors like prothrombin. Insufficient vitamin K impairs clotting and can lead to excessive bleeding. Newborns are given a vitamin K shot to prevent deficiency bleeding.
Understanding the Two Main Forms: K1 and K2
Vitamin K1 comes from plant sources, mainly green leafy vegetables, and is crucial for liver clotting function. Eating K1 with fat enhances absorption. Vitamin K2 is found in fermented foods, meat, eggs, and made by gut bacteria. Besides clotting, K2 supports bone health by activating osteocalcin.
The Health Implications of Vitamin K Deficiency
Though uncommon in healthy adults, deficiency can occur with conditions causing fat malabsorption or from certain medications like antibiotics. Symptoms include easy bruising, excessive bleeding from various sources, and blood in urine or stool.
Comparing Vitamin K1 and K2
| Feature | Vitamin K1 (Phylloquinone) | Vitamin K2 (Menaquinone) | 
|---|---|---|
| Primary Source | Green leafy vegetables | Fermented foods, meat, eggs, and gut bacteria | 
| Main Function | Essential for liver synthesis of clotting factors | Supports blood clotting, bone, and cardiovascular health | 
| Absorption Site | Primarily absorbed in the small intestine | Primarily synthesized in the large intestine and absorbed from food | 
| Cardiovascular Impact | Associated with lower heart disease risk in some studies | May help prevent arterial calcification | 
| Bone Health | Contributes indirectly via overall vitamin K status | Directly involved in activating bone proteins like osteocalcin | 
Dietary Sources of Vitamin K
Good sources of K1 include kale, spinach, broccoli, and vegetable oils. K2 is found in natto, liver, eggs, and cheese. Pairing K1-rich foods with fat improves absorption. Most healthy adults meet their needs with a balanced diet. Those on warfarin should maintain consistent intake and consult a doctor.
Beyond Clotting: Other Health Benefits
Vitamin K is also being studied for its potential roles in bone strength and preventing cardiovascular disease by inhibiting arterial calcification.
Conclusion: Maintaining Your Clotting Capability
Vitamin K is the key vitamin for blood clotting, supporting wound healing and overall health. Getting enough K1 from leafy greens and K2 from fermented foods and animal products is important for clotting, bone health, and possibly heart health. Always consult a healthcare professional for health concerns. More information is available on the NIH Office of Dietary Supplements fact sheet on Vitamin K.