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What are the ingredients in Tri Heart Plus?

2 min read

Heartworm disease is a serious, life-threatening condition for dogs that can be prevented with monthly medication. The medication, Tri Heart Plus, is a popular preventive option, but many owners wonder: what are the ingredients in Tri Heart Plus and how do they work?

Quick Summary

Tri Heart Plus is a dog heartworm preventive containing Ivermectin and Pyrantel Pamoate. This combination offers protection against heartworm disease, roundworms, and hookworms.

Key Points

  • Active Ingredients: Tri Heart Plus contains the active ingredients Ivermectin and Pyrantel Pamoate.

  • Broad Spectrum Protection: The medication prevents heartworm disease and treats/controls roundworms and hookworms.

  • Monthly Dosing: It is administered as a monthly, beef-flavored chewable tablet.

  • Prescription Required: This medication is only available via a prescription from a licensed veterinarian.

  • Heartworm Test Prerequisite: Dogs should be tested for existing heartworm infection before beginning treatment.

  • Herding Breed Sensitivity: Certain dog breeds, like collies, may have sensitivities to the ivermectin component.

In This Article

Tri Heart Plus is a widely prescribed, beef-flavored chewable tablet used by veterinarians to protect dogs from dangerous internal parasites. Its effectiveness stems from a dual-action formula, combining two powerful anthelmintic agents: Ivermectin and Pyrantel Pamoate. These active ingredients work synergistically to provide comprehensive protection against heartworm and several common intestinal worms. Understanding the role of each component is key to appreciating how this monthly medication keeps your canine companion healthy and safe.

The Active Ingredients Explained

Ivermectin: The Heartworm Preventative

Ivermectin is a broad-spectrum anti-parasitic agent that primarily targets and eliminates the tissue stage of heartworm larvae. This prevents them from maturing into adult heartworms which can severely damage a dog's heart and lungs. Ivermectin works by disrupting the parasite's nervous system. While generally safe, some herding breeds may have a sensitivity at higher doses.

Pyrantel Pamoate: Targeting Intestinal Parasites

Pyrantel Pamoate is an anthelmintic effective against common intestinal worms like roundworms and hookworms. It paralyzes these parasites in the gastrointestinal tract, allowing them to be expelled from the body. The combination of Ivermectin and Pyrantel Pamoate provides comprehensive protection with a single chewable tablet.

How Tri Heart Plus Protects Your Dog

Tri Heart Plus provides a monthly defense against:

  • Heartworm Disease: Kills heartworm larvae acquired in the previous month.
  • Roundworm Infestations: Treats and controls infections by common roundworm species.
  • Hookworm Infestations: Treats and controls infections by various hookworm species.

Comparison: Tri Heart Plus vs. Heartgard Plus

Both Tri Heart Plus and Heartgard Plus contain the same active ingredients. The table below highlights some key distinctions:

Feature Tri Heart Plus Heartgard Plus
Active Ingredients Ivermectin & Pyrantel Pamoate Ivermectin & Pyrantel Pamoate
Parasites Treated Heartworms, Roundworms, Hookworms Heartworms, Roundworms, Hookworms
Formulation Beef-flavored chewable tablet Beef-flavored chewable tablet
Prescription Required? Yes Yes
Manufacturer Merck Animal Health Boehringer Ingelheim
Potential Price Often more economical May be priced differently

Important Considerations and Potential Side Effects

A veterinary consultation is crucial before starting Tri Heart Plus, as your dog must be tested for existing heartworm infection. Giving this medication to a heartworm-positive dog can cause severe reactions. Administer monthly doses around the same date.

Tri Heart Plus is generally safe for most dogs, including puppies from 6 weeks and pregnant females. However, rare side effects can include:

  • Digestive issues (e.g., vomiting, diarrhea)
  • Neurological signs (e.g., staggering, lethargy)

Contact your veterinarian for any unusual symptoms. Herding breeds with the MDR1 gene mutation may have increased sensitivity to ivermectin.

Conclusion

Tri Heart Plus's effectiveness in preventing heartworm disease and controlling intestinal roundworms and hookworms is due to its active ingredients, Ivermectin and Pyrantel Pamoate. By working with your veterinarian to ensure proper use, you can protect your dog from these parasites. For detailed product information, refer to the manufacturer's resources Merck Animal Health.

Frequently Asked Questions

The two active ingredients in Tri Heart Plus are Ivermectin, which prevents heartworm disease, and Pyrantel Pamoate, which controls and treats intestinal roundworms and hookworms.

Tri Heart Plus prevents heartworm disease by killing the larvae and treats and controls intestinal roundworms (Toxocara canis, Toxascaris leonina) and hookworms (Ancylostoma caninum, Uncinaria stenocephala, Ancylostoma braziliense).

Tri Heart Plus contains the same active ingredients (Ivermectin and Pyrantel) as Heartgard Plus, offering a comparable and often more economical option for heartworm prevention and intestinal parasite control.

Tri Heart Plus is an FDA-licensed product deemed safe and effective when used as recommended by a veterinarian. All dogs must be tested for existing heartworm infection before starting treatment.

If a dose is missed, its efficacy can be reduced. It is important to give the missed dose as soon as you remember and contact your veterinarian for advice on how to proceed, especially if more than 30 days have passed.

Side effects are rare but can include digestive issues such as vomiting, diarrhea, or anorexia, as well as neurological signs like staggering or lethargy. If adverse reactions occur, contact your veterinarian immediately.

Certain herding breeds, such as collies, may have a genetic sensitivity to ivermectin. Your veterinarian may advise you to monitor your dog for several hours after giving the medication, especially with higher doses.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.