The Chemical Identity: Sunset Yellow FCF
Yellow 6 is a synthetic substance officially named Sunset Yellow FCF. Its chemical name is disodium 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonate, classifying it as an azo dye due to its –N=N– group connecting two aromatic rings.
This dye is synthesized from petroleum precursors. The process involves diazotizing 4-aminobenzenesulfonic acid with sodium nitrite in acid, then coupling this with 6-hydroxy-2-naphthalenesulfonic acid. The final product is a sodium salt isolated and dried into a powder.
Principal and Subsidiary Components
Commercial Yellow 6 has a minimum purity, often over 87% required by regulators like the FDA. The remaining content includes minor coloring compounds formed during synthesis, and uncolored salts like sodium chloride or sodium sulfate, which are residues from processing. An insoluble aluminum lake form is also produced for specific uses.
The Controversial Benzidine Contaminant
Trace amounts of benzidine, a known carcinogen, can be found in Yellow 6 and other azo dyes. While these levels are regulated and typically low, concerns exist regarding potential long-term health effects.
Forms and Applications of Yellow 6
Yellow 6 is available as a water-soluble powder and an insoluble aluminum lake, each suited for different applications.
| Feature | Water-Soluble Powder | Aluminum Lake | 
|---|---|---|
| Physical State | Free-flowing powder or granules | Insoluble pigment | 
| Appearance | Reddish-orange to red powder | Varies based on the specific salt used | 
| Solubility | Highly soluble in water | Insoluble in water | 
| Primary Use | Beverages, baked goods, cereals, desserts | Cosmetic coatings, dry mixes, compressed tablets | 
| Regulatory Notes | Subject to batch certification in the US | Permitted in the EU and US for specific uses | 
Alternatives and Regulation
Natural colorants such as curcumin, annatto, beta-carotene, and saffron can be used as alternatives to achieve yellow and orange colors. Regulatory approaches vary globally; the FDA allows Yellow 6 in food, drugs, and cosmetics, while the EU uses the designation E110 and mandates a warning label about potential hyperactivity in children.
Conclusion
The primary ingredient in Yellow 6 dye is Sunset Yellow FCF, a synthetic azo compound derived from petroleum through a specific chemical manufacturing process. While primarily composed of this colorant, it also contains minor colorants and processing residues. Concerns about contaminants like benzidine have led to increased interest in natural alternatives like turmeric and annatto.
For more information on azo dyes, the National Center for Biotechnology Information's PubChem database is an authoritative source on chemical compounds like Sunset Yellow FCF.