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What Happens If You Don't Take B12 as a Vegan?

4 min read

According to the National Institutes of Health, vitamin B12 deficiency can take several years to appear because the body stores a significant amount of this nutrient in the liver. However, a persistent lack of B12 can lead to serious and potentially irreversible health consequences for vegans who do not supplement or consume fortified foods.

Quick Summary

Long-term veganism without a reliable B12 source can cause severe deficiency, leading to anemia and nerve damage, which can be permanent. Fortified foods and supplements are critical to ensure a sufficient intake of this essential nutrient.

Key Points

  • Irreversible Neurological Damage: Severe and long-term B12 deficiency can lead to permanent nerve damage, affecting balance, coordination, memory, and cognitive function.

  • Masked Deficiency: The body stores B12 in the liver for several years, allowing a deficiency to go unnoticed and untreated for an extended period.

  • Anemia Risk: A lack of B12 hinders the production of healthy red blood cells, leading to megaloblastic anemia, which causes fatigue, weakness, and other debilitating symptoms.

  • Reliable Sources are Key: The only proven reliable vegan sources of B12 are fortified foods (like plant milks, cereals, and nutritional yeast) and supplements.

  • Infant Vulnerability: Breastfed infants of B12-deficient vegan mothers are at particularly high risk and can suffer permanent developmental damage if not addressed promptly.

  • Accurate Testing is Essential: Standard serum B12 tests can be misleading for vegans. More specific markers like methylmalonic acid (MMA) should be used for accurate diagnosis.

  • Supplementation Options: Vegans can choose between regular intake of fortified foods or daily/weekly B12 supplements to meet their needs effectively.

In This Article

The Critical Role of B12 in the Body

Vitamin B12, also known as cobalamin, is a water-soluble vitamin that is vital for several physiological processes, including nerve function, DNA synthesis, and the formation of healthy red blood cells. Unlike most vitamins, B12 is produced by micro-organisms and is not naturally present in plant foods. The human body stores B12 in the liver, which can mask the signs of deficiency for years, creating a false sense of security for uninformed vegans. A deficiency is particularly dangerous for infants of vegan mothers, where the onset of serious issues is much more rapid.

Symptoms of B12 Deficiency

When B12 stores are depleted, a range of symptoms can appear, affecting the physical, neurological, and psychological well-being of an individual. These symptoms can be subtle at first, often mistaken for other ailments like stress or aging.

Early-stage symptoms include:

  • Fatigue and Weakness: A persistent feeling of tiredness, even after adequate rest.
  • Pins and Needles (Paresthesia): A tingling or numbness sensation, particularly in the hands and feet.
  • Cognitive Issues: Difficulty with memory, focus, and concentration, sometimes referred to as 'brain fog'.
  • Sore or Inflamed Tongue: Glossitis, a condition that can cause the tongue to appear red and swollen, may occur.
  • Mouth Ulcers: Sores or ulcers may develop inside the mouth.

Advanced and irreversible consequences:

Left untreated, B12 deficiency can lead to severe and potentially irreversible health problems, including permanent neurological damage and heart conditions. Nerve damage can affect balance and coordination (ataxia), vision, and lead to confusion and dementia-like symptoms. In severe cases, it can result in peripheral neuropathy, spinal cord degeneration, and even paralysis. Infants born to B12-deficient vegan mothers are at risk of retarded development and can suffer permanent damage.

Diagnosing a B12 Deficiency

Many healthcare professionals rely on a serum B12 level test, but for vegans, this can be an unreliable measure, especially if they consume fortified foods with B12 analogues. A more accurate diagnosis involves a combination of tests:

  • Methylmalonic Acid (MMA) Test: Elevated MMA levels in the blood or urine are a more specific indicator of B12 deficiency.
  • Homocysteine Test: High homocysteine levels in the blood can also signal a deficiency, though it is less specific than MMA.
  • Holotranscobalamin II (Holo-TC): This is considered the earliest marker of B12 status and can detect depleted levels before symptoms appear.

Supplementation vs. Fortified Foods

Vegans have two reliable options to maintain healthy B12 levels: supplementation and fortified foods. Both are effective, but they differ in convenience and dosage.

Feature B12 Supplements (e.g., cyanocobalamin) B12 Fortified Foods (e.g., plant milks, cereals)
Dosing Often higher dose, taken less frequently (e.g., 2000mcg weekly or 10-50mcg daily). Smaller doses, consumed frequently throughout the day with meals.
Absorption Small doses are absorbed more efficiently; large doses use passive diffusion. Efficient absorption when consumed in small, regular amounts.
Reliability Consistent and quantifiable dosage makes it a very reliable source. Requires careful label reading to ensure consistent daily intake.
Convenience Can be more convenient for those who prefer to not track fortified food intake daily. Requires integrating fortified products into the daily diet, which is easy for many.
Cost Often economical for long-term use. Costs can vary depending on brand and consumption patterns.

Reliable Vegan Sources of B12

To prevent deficiency, vegans must include reliable sources of B12 in their diet. Relying on unfortified fermented foods or algae like spirulina has been shown to be unreliable and potentially counterproductive due to the presence of inactive B12 analogues.

Key sources include:

  • Fortified Plant-Based Milks: Many soy, almond, and oat milks are fortified with B12. Always check the nutrition label.
  • Fortified Breakfast Cereals: A quick and easy source of B12, perfect for daily intake.
  • Nutritional Yeast: Look for nutritional yeast flakes specifically fortified with B12, as unfortified versions do not contain it.
  • Fortified Plant Spreads and Meat Alternatives: Certain vegan spreads and meat substitutes also contain added B12.
  • Supplements: These offer a foolproof way to ensure adequate intake, with daily or weekly dosing options available.

Conclusion: The Importance of Proactive B12 Management

Ultimately, a vegan diet is a choice that requires responsible nutritional planning, with B12 at the forefront. While a plant-based diet offers many health benefits, it does not naturally contain this essential vitamin. Failing to take B12 as a vegan can lead to a long-term, slow-onset deficiency with potentially irreversible consequences, particularly involving the nervous system. By consistently incorporating fortified foods or a regular supplement, vegans can confidently and safely meet their B12 requirements and avoid serious health risks. It is crucial for all vegans, regardless of how long they have been on the diet, to be proactive about their B12 intake and to get regular testing to monitor their status.

Resources

For more detailed information on vitamin B12 requirements and supplementation strategies for vegans, visit The Vegan Society's dedicated resource page.

Frequently Asked Questions

Due to the body's ability to store B12 in the liver, it can take several years for a deficiency to manifest. For many, this is 3-5 years, but it can be longer for some.

No, there are no reliable natural plant sources of B12. Claims about sources like spirulina or nori have not been consistently proven to contain the active form of B12 and are not recommended for meeting needs.

Early symptoms often include persistent fatigue, pins and needles or numbness in the extremities, cognitive issues like memory lapses, and mood changes like depression.

Yes, if left untreated, B12 deficiency can lead to irreversible neurological damage, affecting the brain and spinal cord. In severe cases, this can result in permanent memory loss, nerve damage, and other serious issues.

Yes, it is possible to get enough B12 from fortified foods, but it requires consistently consuming them multiple times per day and carefully checking nutrition labels. Many vegans find supplements a more reliable and convenient method.

While a serum B12 test can be a starting point, more specific and reliable tests for vegans include measuring methylmalonic acid (MMA) and homocysteine levels, as high folate intake can mask B12 deficiency symptoms in standard blood counts.

Yes, because animal products are the primary natural source of B12, all vegans must either consistently consume fortified foods or take a B12 supplement to prevent deficiency and its associated health risks.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.