The Identity of Colecalciferol: Vitamin D3
Colecalciferol is often called cholecalciferol or Vitamin D3. This fat-soluble vitamin is made in the body when skin is exposed to UVB rays from sunlight and is also found in some foods and supplements. Vitamin D3 is considered more effective than Vitamin D2 (ergocalciferol) at raising vitamin D levels in people.
How Your Body Synthesizes Colecalciferol
When skin is exposed to UVB radiation, 7-dehydrocholesterol is turned into colecalciferol. The body controls this process to prevent toxic levels from too much sun exposure. Various things like where you live, skin color, age, and sunscreen affect how much is made.
The Importance of Colecalciferol for Health
Colecalciferol is changed in the body to calcitriol, which is important for several functions:
- Calcium and Phosphate: Helps the body take in calcium and phosphorus, which are key for healthy bones and teeth.
- Bone Health: Helps stop bone problems such as rickets, osteomalacia, and osteoporosis.
- Immune System: Supports the immune system to fight off infections.
- Other Systems: Studies suggest it may help with heart health, mood, and reducing swelling.
Sources of Colecalciferol
Getting enough colecalciferol often needs more than just sun. Sources include {Link: DrugBank https://go.drugbank.com/drugs/DB00169}:
- Fatty Fish: Like salmon, mackerel, and tuna.
- Fish Liver Oils: Such as cod liver oil.
- Egg Yolks and Cheese: Have smaller amounts.
- Fortified Foods: Like milk, cereals, and orange juice.
- Supplements: Available in different types.
Colecalciferol vs. Ergocalciferol: A Comparison
Knowing the difference between the two main kinds of vitamin D is helpful:
| Feature | Colecalciferol (Vitamin D3) | Ergocalciferol (Vitamin D2) |
|---|---|---|
| Origin | Animals and supplements from lanolin or lichen | Plants and fungi exposed to UV radiation |
| Potency in Humans | Generally more effective | Less potent |
| Synthesis | Produced in human skin upon UVB exposure | Produced by irradiating ergosterol |
| Dietary Sources | Fatty fish, egg yolks, fortified foods | Fortified foods, mushrooms, yeast |
| Commercial Use | Common in OTC supplements and fortified foods | Used in supplements, sometimes in prescription doses |
Addressing Colecalciferol Deficiency
Things that increase the chance of deficiency include not getting enough sun, having darker skin, being overweight, being older, and having certain illnesses. A blood test can show if you are deficient. Treatment might mean more sun, changing your diet, or taking supplements. Too much can cause high calcium levels in the blood (hypercalcaemia), leading to symptoms like not wanting to eat, feeling sick, and not being able to go to the bathroom.
Conclusion
Colecalciferol is known as Vitamin D3, a key nutrient for healthy bones and a strong immune system. It's made by the body from sunlight and found in certain foods and supplements. Understanding its role, where to get it, and its other names is important for staying healthy and avoiding deficiencies. If you are worried about your vitamin D levels, talk to a doctor.
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