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What is DoNotAge Pure Fisetin?

3 min read

Over time, our bodies accumulate senescent, or 'zombie,' cells that contribute to age-related decline. DoNotAge Pure Fisetin is a supplement designed to target and eliminate these dysfunctional cells, promoting cellular health and supporting healthy aging.

Quick Summary

DoNotAge Pure Fisetin is a potent supplement containing a highly-pure flavonoid derived from smoketree extract. It functions as a senolytic, targeting age-related senescent cells to support cellular clearance, promote cognitive function, and manage inflammatory pathways for healthy aging.

Key Points

  • Senolytic Function: DoNotAge Pure Fisetin acts as a potent senolytic, helping the body remove dysfunctional, senescent cells.

  • High Purity: The supplement is independently tested to ensure over 99% purity, with no fillers or additives.

  • Cognitive and Cellular Health: It supports brain function, reduces oxidative stress, and helps modulate inflammatory responses associated with aging.

  • Enhanced Absorption: For optimal absorption, the supplement should be taken with a meal containing healthy fats.

  • Research-Focused Brand: DoNotAge is a health research organization committed to providing high-quality, scientifically relevant ingredients for longevity.

  • Vegan Formulation: The product is 100% vegan, using a vegetable cellulose capsule.

In This Article

Understanding Fisetin: The Senolytic Flavonoid

Fisetin is a naturally occurring flavonoid found in fruits and vegetables like strawberries and apples. It is known for its antioxidant properties and its role as a potent senolytic. Senescent cells, often called 'zombie cells,' are damaged cells that don't die and can release inflammatory compounds. Fisetin is thought to support their removal, potentially mitigating age-related issues. Research suggests fisetin supports healthy aging by aiding cellular processes such as senescent cell clearance, antioxidant support, inflammatory response modulation, mitochondrial function, and cognitive enhancement.

What Makes DoNotAge's Pure Fisetin Unique?

DoNotAge.org highlights research-grade quality. Key features of their fisetin product include: high purity (often exceeding 99%) tested by third-party labs, a clean formulation from smoketree extract ($Cotinus coggygria$) in a vegetable capsule without fillers or additives. DoNotAge suggests taking their fisetin with a source of fat to enhance absorption. The product is produced following GMP and ISO9001 standards and is vegan and non-GMO.

DoNotAge Pure Fisetin vs. Other Fisetin Supplements

Feature DoNotAge Pure Fisetin Other Commercial Fisetin Supplements
Purity Independently tested, often >99% pure. Purity levels can vary; fillers may be present.
Formulation Pure fisetin (from smoketree) in a vegetable capsule; no fillers. May contain additives or absorption enhancers.
Research Foundation Developed with research standards; used in trials. May have less research focus or independent testing.
Brand Focus Dedicated to longevity research. Can be general supplement companies.

Conclusion: Making an Informed Choice

DoNotAge Pure Fisetin is a senolytic supplement focusing on high purity and transparency. It may be considered by those seeking an additive-free product for longevity, cognitive support, and cellular health, primarily by supporting the clearance of senescent cells. Always consult a healthcare professional before starting any new supplement. Key considerations for choosing a fisetin supplement involve purity, absorption method, and brand focus. More information on fisetin's properties can be found at {Link: NCBI PMC https://pmc.ncbi.nlm.nih.gov/articles/PMC6197652/}. For details on DoNotAge's product, refer to {Link: DoNotAge.org https://donotage.org/pure-fisetin}.

What is DoNotAge Pure Fisetin?: A Quick Guide

Heading: High-purity flavonoid supplement. Heading: Acts as a senolytic, targeting 'zombie cells'. Heading: Sourced from smoketree extract. Heading: Purity often over 99%, independently tested. Heading: Absorption enhanced by taking with fat. Heading: Supports cognitive and cellular health. Heading: Brand focuses on longevity research.

Frequently Asked Questions About DoNotAge Pure Fisetin

Q: What is the main purpose of DoNotAge Pure Fisetin? A: To act as a senolytic, helping clear senescent cells contributing to aging.

Q: How is DoNotAge Fisetin purity verified? A: Purity is verified through in-house and third-party lab testing.

Q: How should I take it for best results? A: Taking with a fat-containing meal may improve absorption.

Q: Are there fillers in the capsules? A: No, they contain only pure fisetin in a vegetable capsule.

Q: Can I get enough Fisetin from my diet? A: Dietary concentrations are low; supplementation may be considered for those seeking higher intake.

Q: Is it suitable for vegans? A: Yes, it is 100% vegan.

Q: How does Fisetin support cognitive function? A: Fisetin may support cognitive function by protecting brain cells and potentially improving memory.

Q: What is the recommended way to use this supplement? A: It is recommended to follow the guidance provided by a healthcare professional or the product labeling.

Frequently Asked Questions

Fisetin's main benefit for longevity is its senolytic activity, which means it helps clear the body of senescent 'zombie' cells. This reduces the inflammation and tissue damage these dysfunctional cells cause, promoting a healthier aging process.

A dietary intake of fisetin is minimal. To potentially achieve similar levels as a supplement, one would need to consume a very large quantity of fisetin-rich foods like strawberries, making supplementation an alternative option.

A senolytic is a compound that selectively induces apoptosis, or programmed cell death, in senescent cells. This is important because senescent cells, which don't die on their own, can harm surrounding healthy tissue by releasing inflammatory signals. Clearing them can improve tissue function and healthspan.

Yes, taking with a meal that contains a source of fat may improve the supplement's absorption into the bloodstream.

DoNotAge states that its Pure Fisetin is non-GMO and free from common allergens like gluten, soy, wheat, yeast, and dairy.

Fisetin may support cognitive function by protecting brain cells from oxidative stress and inflammation, promoting neuronal health, and potentially enhancing memory and focus. Its ability to cross the blood-brain barrier is a key factor in these effects.

It is advisable to follow the guidance provided by a healthcare professional or the product labeling when using this supplement.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.