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What is the Bioavailability Score of Soy Protein?

4 min read

According to a recent review published in PMC, soy protein consistently receives high scores on modern protein quality scales like DIAAS, rating as a high-quality plant-based protein. Understanding the bioavailability score of soy protein requires looking beyond simple metrics and considering factors like processing and the specific scoring method used for evaluation.

Quick Summary

Explores the various methods used to measure soy protein's nutritional quality, including the older PDCAAS and more accurate DIAAS. Details how factors like processing, antinutrients, and product type impact its final score and overall digestibility.

Key Points

  • High-Quality Protein: Soy is a complete plant protein, containing all nine essential amino acids required by the body.

  • Impressive Scores: Modern soy products, especially isolates, achieve high scores on both the older PDCAAS (up to 1.00) and more accurate DIAAS (often >90) scales.

  • Processing is Key: Methods like heat treatment, isolation, and fermentation significantly improve soy protein's bioavailability by deactivating antinutrients and enhancing digestibility.

  • Isolate vs. Concentrate: Soy protein isolate offers a more concentrated protein source (>90%) with higher bioavailability than soy protein concentrate (~70%).

  • Health Benefits: Beyond its high protein quality, soy is known to support heart health by lowering LDL cholesterol and can support muscle growth comparable to whey protein when supplemented correctly.

In This Article

Protein quality is a critical consideration for anyone managing their nutrition, especially those relying on plant-based sources. The term "bioavailability score" refers to a protein's digestibility and its ability to provide indispensable amino acids (IAAs) in the right proportions to meet the body's needs. For soy protein, these scores are impressively high for a plant-based source, but the details reveal a nuanced picture.

Understanding Protein Bioavailability Assessment

There are several methods for determining a protein's quality, but two stand out as the most relevant in modern nutrition science: the Protein Digestibility-Corrected Amino Acid Score (PDCAAS) and the Digestible Indispensable Amino Acid Score (DIAAS).

The Older Method: Protein Digestibility-Corrected Amino Acid Score (PDCAAS)

Developed in 1993, the PDCAAS was the gold standard for many years. It rates protein quality by comparing a protein's essential amino acid profile to a reference amino acid profile and correcting for fecal digestibility. The score is capped at 1.00, which led to high-quality proteins like milk and soy being given the same maximum score, even though some may offer superior nutritional value. A typical soy protein isolate can achieve a PDCAAS of 1.00. However, this method has limitations, primarily that it overestimates quality because it relies on fecal digestibility, which includes amino acids that are not absorbed by the body but are consumed by gut bacteria.

The Modern Method: Digestible Indispensable Amino Acid Score (DIAAS)

Recommended by the FAO in 2011, the DIAAS is a more accurate measure of protein quality. It addresses the limitations of PDCAAS by measuring the digestibility of individual amino acids at the ileum (the end of the small intestine), providing a more precise value for the amino acids absorbed by the body. Unlike PDCAAS, DIAAS is not capped at 100, allowing for a more accurate comparison of excellent quality proteins.

For soy products, DIAAS values vary significantly depending on the specific product and processing, with values ranging from the mid-80s to over 100 for high-quality, post-processed products like soy protein concentrate. On average, studies cite a mean DIAAS for total soy products around 84.5 (based on the scoring pattern for children aged 0.5–3 years), classifying it as a high-quality protein.

The Bioavailability Score of Soy Protein: Factors That Matter

The final bioavailability score of soy protein is not a single number but depends on several key factors:

  • Antinutritional Factors (ANFs): Raw soybeans contain antinutrients like trypsin inhibitors and lectins, which can interfere with protein digestion and absorption. Proper heat treatment is crucial for deactivating these compounds and significantly improving digestibility.
  • Processing Methods: Different processing techniques alter soy's protein structure and ANF content. Isolation and fermentation are particularly effective at improving digestibility and increasing amino acid availability.
  • Product Type: The form of soy consumed makes a difference. Refined products like soy protein isolate have higher protein concentration and improved digestibility compared to less processed forms like soy flour or soy protein concentrate. Fermented soy products, such as miso and tempeh, also have enhanced bioavailability.

Soy Protein Isolate vs. Concentrate: Bioavailability Differences

The level of processing directly correlates with protein concentration and impacts bioavailability.

  • Soy Protein Isolate: This is the most refined form of soy protein, containing over 90% protein. The manufacturing process removes most fats and carbohydrates, including many antinutritional factors. This extensive processing results in a product with very high digestibility and amino acid availability, making it ideal for supplements and muscle recovery.
  • Soy Protein Concentrate: Containing around 70% protein, concentrate undergoes less processing than isolate. It retains more fiber and other natural nutrients but has a lower protein content per gram and slightly lower digestibility compared to the isolate due to higher levels of antinutrients. It is often used in food products to boost protein content rather than as a primary, fast-absorbing supplement.

Comparison of Protein Quality Scores

To understand where soy fits in, comparing its scores to other common protein sources is helpful. While the older PDCAAS can be misleading due to its cap, the DIAAS provides a more accurate picture, showing soy as a very high-quality plant-based protein.

Protein Source Typical PDCAAS Score Limiting Amino Acid Typical DIAAS Score Notes
Soy Protein Isolate 1.00 Sulfur-containing AAs (Methionine+Cysteine) ~90-100+ Highly refined with excellent digestibility
Whey Protein Isolate 0.90–1.00 Histidine ~100+ Gold standard for animal protein quality
Casein 1.00 None ~117 Excellent, slow-digesting animal protein
Pea Protein 0.66–0.91 Sulfur-containing AAs (Met+Cys), Tryptophan ~70 Often combined with other proteins to boost score
Whole Egg 1.00 None ~101 Complete protein standard

Health Benefits Beyond Bioavailability

Beyond just protein quality, soy offers additional health benefits that are independent of its bioavailability score.

  • Heart Health: Studies have consistently shown that consuming soy protein can help lower LDL cholesterol and reduce the risk of coronary heart disease.
  • Muscle Growth: Research indicates that soy protein supplementation, particularly when matched for leucine content, can lead to similar increases in lean muscle mass and strength compared to whey protein in untrained individuals.
  • Rich Nutrient Profile: Soybeans are a complete protein source containing all nine essential amino acids and are rich in fiber, B-vitamins, iron, and calcium.

Conclusion: A High-Quality Plant-Based Protein

In summary, soy protein boasts a very high bioavailability score, especially when highly processed into isolate form. Its performance on the modern DIAAS scale places it among other high-quality protein sources, both animal and plant-based, and demonstrates its effectiveness in providing digestible amino acids for the body. Factors like processing methods (heat, isolation, fermentation) are key to maximizing its nutritional value by reducing antinutrients and increasing digestibility. Soy's high protein quality, combined with its additional heart-healthy benefits, cements its status as a top-tier option for individuals seeking a complete and effective plant-based protein source. For further insights into the effectiveness of soy versus other protein sources in athletic training, consult this study from the National Institutes of Health.

Frequently Asked Questions

Soy protein, particularly in its isolated form, has a Protein Digestibility-Corrected Amino Acid Score (PDCAAS) of up to 1.00, which was the highest possible score under this older system.

The Digestible Indispensable Amino Acid Score (DIAAS) measures the digestibility of individual indispensable amino acids at the ileum. Scores for soy products can vary, but generally rate highly, often exceeding 90 for refined forms.

Processing methods like heat treatment, fermentation, and isolation increase soy protein's bioavailability. They deactivate antinutrients, such as trypsin inhibitors, and break down complex structures, making the amino acids more accessible and digestible.

Soy protein isolate has a higher bioavailability score and protein concentration (over 90%) than soy protein concentrate (about 70%). The extensive processing to create isolate removes more antinutrients and other compounds that can hinder absorption.

While whey is often considered the gold standard, soy protein, particularly isolate, compares very favorably. On the more modern DIAAS scale, high-quality soy products achieve excellent scores that are comparable to many animal proteins.

Raw soybeans contain antinutrients that can limit digestibility. However, these are largely eliminated through standard processing, including heat treatment. The presence of cell walls in less processed forms can also slightly decrease absorption.

Yes, research has shown that soy protein supplementation can support muscle growth and strength development in resistance training comparable to whey protein, especially when matched for leucine content.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.