Skip to content

What is the difference between parenteral and enteral nutrition?

5 min read

According to the American College of Gastroenterology, enteral nutrition is the preferred method of feeding when the gastrointestinal (GI) tract is functional. The primary difference between parenteral and enteral nutrition lies in the delivery method, with one using the digestive system and the other bypassing it completely.

Quick Summary

This article explains the fundamental differences between parenteral and enteral nutrition, comparing the delivery routes, medical indications, potential complications, and factors influencing the choice of feeding method for patients.

Key Points

  • Delivery Route: Enteral nutrition uses the GI tract via tube, while parenteral nutrition delivers nutrients directly into the bloodstream via IV.

  • GI Tract Function: Enteral nutrition requires a functional gut; parenteral is for when the GI tract is non-functional or inaccessible.

  • Risk Profile: Parenteral nutrition carries a higher risk of serious complications like bloodstream infections, while enteral has a lower risk profile.

  • Cost and Complexity: Enteral feeding is generally less expensive and complex, whereas parenteral feeding requires specialized, costly formulas and careful monitoring.

  • Clinical Preference: Medical professionals prefer enteral nutrition when possible due to its safety and ability to preserve gut integrity.

  • Decision Factors: The choice of nutrition depends on the patient's clinical status, duration of feeding, and GI tract functionality.

In This Article

What is Enteral Nutrition?

Enteral nutrition (EN) is a method of providing nutritional support that utilizes the gastrointestinal (GI) tract. The term 'enteral' literally means 'within or by way of the intestines.' It encompasses everything from oral liquid supplements to tube feedings that deliver nutrients directly into the stomach or small intestine. This method is the preferred option when a patient's GI tract is functional but they are unable to consume adequate nutrients orally due to a medical condition.

Types of Enteral Nutrition Access

Enteral feeding can be delivered through several access points, depending on the patient's needs and the expected duration of the feeding. Common methods include:

  • Nasogastric (NG) tube: A tube is passed through the nose, down the esophagus, and into the stomach. This is typically used for short-term feeding, usually less than 4-6 weeks.
  • Gastrostomy tube (G-tube): A tube is surgically or endoscopically placed directly into the stomach through the abdominal wall. This is a common choice for long-term enteral nutrition.
  • Jejunostomy tube (J-tube): A tube is placed into the jejunum, a part of the small intestine. This is used when the stomach is not a suitable site for feeding, often in patients with gastric motility issues or a high risk of aspiration.

What is Parenteral Nutrition?

Parenteral nutrition (PN), also known as total parenteral nutrition (TPN) or hyperalimentation, is the intravenous administration of nutrients, bypassing the digestive system entirely. The term 'parenteral' means 'outside of the digestive tract.' This method is reserved for patients whose GI tract is non-functional or severely compromised and cannot safely absorb nutrients. PN formulas are complex and contain a balance of carbohydrates, proteins, fats, vitamins, minerals, and electrolytes, delivered directly into the bloodstream.

Types of Parenteral Nutrition Access

Parenteral nutrition is administered via a central or peripheral vein, with the choice depending on the duration and type of formula. The main access types are:

  • Central Venous Access: For total parenteral nutrition (TPN), a central venous catheter (CVC) is placed into a large, central vein, often in the neck, chest, or groin. A peripherally inserted central catheter (PICC) is a common type of CVC used for long-term PN.
  • Peripheral Venous Access: For partial parenteral nutrition (PPN), a catheter is placed in a smaller, peripheral vein, usually in the arm. PPN is for short-term use and provides a less concentrated nutrient solution than TPN.

Comparison Table: Enteral vs. Parenteral Nutrition

Feature Enteral Nutrition Parenteral Nutrition
Delivery Route Uses the gastrointestinal (GI) tract. Bypasses the GI tract, delivered intravenously.
GI Tract Function Requires a functional GI tract. Used when the GI tract is non-functional or cannot be used safely.
Risk of Infection Lower risk of systemic infection, though localized infections can occur at tube sites. Higher risk of catheter-related bloodstream infections (CRBSI).
Cost Generally less expensive. More expensive due to specialized formulas and delivery equipment.
Complications Mechanical (tube clogging), GI issues (diarrhea), aspiration pneumonia, refeeding syndrome. Catheter-related issues, liver complications, electrolyte imbalances, metabolic bone disease, refeeding syndrome.
Physiological Effect More physiological, helping to maintain gut integrity. Less physiological, as it bypasses normal digestive processes.
Examples Tube feedings via NG, G-tube, or J-tube. Intravenous drip, TPN, PPN.

Which Method is Preferred and Why?

When possible, enteral nutrition is the preferred method for nutritional support. It is generally safer, less expensive, and associated with fewer serious complications compared to parenteral nutrition. By utilizing the gut, EN helps maintain the integrity of the gastrointestinal mucosa, which in turn helps prevent bacterial translocation and infection. The body's normal digestive and metabolic processes are also better preserved with enteral feeding.

Parenteral nutrition, while vital for certain patients, is an invasive therapy with significant risks, including life-threatening bloodstream infections and metabolic complications. It is reserved for specific clinical situations, such as:

  • Severe malabsorption: Conditions like Crohn's disease or short bowel syndrome where the gut cannot absorb enough nutrients.
  • Gastrointestinal obstruction: When a blockage prevents the movement of food through the digestive tract.
  • Bowel rest: For conditions requiring the GI tract to be completely rested, such as severe pancreatitis or fistulas.
  • Inability to access the GI tract: In cases of severe trauma, burns, or neurological impairment affecting swallowing.

The Decision-Making Process

The decision to use enteral or parenteral nutrition is a complex one, made by a medical team based on a thorough assessment of the patient's condition. Factors considered include:

  • GI tract function: Is the gut working and safe to use?
  • Duration of feeding: Will the patient require nutritional support for a short or long period?
  • Nutritional needs: Are the patient's caloric and nutrient needs high, or can they be met with a less intensive method?
  • Risk factors: What is the patient's risk of developing complications associated with each method?

Sometimes, a combination of both enteral and parenteral nutrition may be used to provide adequate nutrition as a patient recovers.

Conclusion

The difference between parenteral and enteral nutrition is centered on the route of administration, with enteral feeding using the gut and parenteral bypassing it via a vein. While enteral nutrition is the safer, more physiological, and less costly option, parenteral nutrition is a critical, life-saving intervention for patients with non-functional or inaccessible GI tracts. Understanding the distinctions in delivery, indications, and associated risks is crucial for making informed clinical decisions about nutritional support. The choice between these two methods is always based on the individual patient's medical needs and condition, guided by expert medical advice.

Choosing the Right Nutrition Method

For medical professionals, determining the correct nutritional support is paramount. When considering the path forward for a patient, it is essential to review the functionality of their gastrointestinal system, their specific nutritional requirements, and the potential risks associated with each method. A nutrition support team can provide invaluable expertise in tailoring a plan that optimizes recovery and minimizes complications. For more in-depth clinical information on nutritional support, please consult authoritative medical guidelines.

American College of Gastroenterology guidelines

The Role of a Nutrition Support Team

In many hospital settings, a multidisciplinary nutrition support team is involved in managing patients on specialized nutrition. This team typically includes dietitians, pharmacists, and physicians who work together to formulate the correct nutrient mixture, monitor patient response, and manage any complications that arise. Their expertise is especially critical for patients receiving parenteral nutrition, given its higher risk profile and metabolic complexity.

Transitioning Between Nutrition Types

Patients may not stay on one type of nutritional support indefinitely. A common clinical goal is to transition a patient from parenteral to enteral nutrition as their gastrointestinal function improves. This gradual process involves reducing the intravenous feeding while slowly increasing the tube feeding until the gut is capable of handling all nutritional needs. This approach minimizes metabolic stress and supports the recovery of normal gut function.

Frequently Asked Questions

The primary difference lies in the delivery method. Enteral nutrition uses the gastrointestinal (GI) tract to deliver nutrients, often via a feeding tube. Parenteral nutrition bypasses the GI tract entirely, delivering nutrients directly into the bloodstream through a vein.

Parenteral nutrition is used when a patient's GI tract is non-functional, inaccessible, or severely compromised. Examples include severe malabsorption disorders, bowel obstructions, or when the GI tract needs to be rested, such as in severe pancreatitis.

Enteral nutrition is generally considered safer than parenteral nutrition. It carries a lower risk of serious complications, particularly bloodstream infections, and is less invasive than placing a central venous catheter.

Yes. Enteral nutrition can be delivered via different tubes, such as nasogastric, gastrostomy, or jejunostomy tubes. Parenteral nutrition can be delivered through a central or peripheral vein, leading to classifications like TPN (total parenteral nutrition) or PPN (partial parenteral nutrition).

Common complications include mechanical issues like tube clogging, gastrointestinal problems such as diarrhea, and a risk of aspiration pneumonia, particularly in patients with swallowing difficulties.

Parenteral nutrition carries a higher risk of complications, including bloodstream infections related to the catheter, liver complications, electrolyte imbalances, and metabolic issues like hyperglycemia.

Yes, it is possible for a patient to receive a combination of both enteral and parenteral nutrition. This is often done to supplement a patient's nutritional intake as their GI function recovers, with the goal of eventually transitioning to full enteral feeding.

References

  1. 1
  2. 2
  3. 3
  4. 4

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.