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What is the difference between PDCAAS and DIAAS score?

5 min read

The Food and Agriculture Organization (FAO) formally recommended replacing the older Protein Digestibility Corrected Amino Acid Score (PDCAAS) with the Digestible Indispensable Amino Acid Score (DIAAS) in 2013. This change aimed to address significant limitations in how we measure protein quality, marking a new era in nutritional science.

Quick Summary

This article breaks down the key distinctions between PDCAAS and DIAAS, the two primary methods for evaluating protein quality. It compares their calculation methods, testing procedures, and the accuracy of their results to help clarify which score is more reliable for assessing nutritional value.

Key Points

  • Measurement Location: DIAAS uses ileal digestibility (end of the small intestine) for a more accurate absorption measure, while PDCAAS uses fecal digestibility, which overestimates quality.

  • Score Truncation: Unlike PDCAAS, which caps all high-quality protein scores at 1.0, DIAAS is untruncated, allowing for a clearer ranking of superior proteins.

  • Individual vs. Average: DIAAS measures the digestibility of each individual amino acid, whereas PDCAAS uses a single value for overall protein digestibility.

  • Reference Patterns: DIAAS uses multiple age-specific amino acid requirement patterns, providing more relevant data than the single pattern used by PDCAAS.

  • Animal Models: DIAAS testing uses pigs, a better model for human digestion, compared to the rats traditionally used for PDCAAS testing.

  • Accuracy: DIAAS provides a more accurate and reliable indicator of protein quality and biological value compared to the outdated PDCAAS method.

In This Article

Understanding the Basics of Protein Scoring

Protein quality is a critical concept in nutrition, as it measures a food protein's ability to provide the indispensable amino acids required for the human body's growth, maintenance, and repair. For decades, the Protein Digestibility Corrected Amino Acid Score (PDCAAS) was the standard for this evaluation. However, the development of the Digestible Indispensable Amino Acid Score (DIAAS) introduced a more accurate and scientifically advanced method. The core of the difference lies in how each system accounts for amino acid digestibility and availability in the human body.

The Legacy Method: PDCAAS

Introduced in 1991, PDCAAS calculates a protein's quality by comparing its amino acid profile to a reference pattern and correcting for fecal protein digestibility. The calculation is based on the single most limiting amino acid in the protein source. The system, capped at a maximum score of 1.0, means that a protein that scores 1.0 is considered to meet or exceed requirements. While straightforward, PDCAAS has notable limitations that spurred the search for a better model:

  • Fecal Digestibility: It uses overall fecal protein digestibility, which fails to account for amino acids that are not absorbed in the small intestine but are instead used by bacteria in the large intestine. This can lead to an overestimation of a protein's quality, as some amino acids measured in fecal matter were never available for the body's use.
  • Score Truncation: The 1.0 maximum score creates a ceiling effect, making it impossible to differentiate between very high-quality protein sources. For instance, both whey and soy protein might receive a score of 1.0, but their true nutritional value is different.
  • Reference Pattern: The reference pattern was based on the amino acid needs of 2- to 5-year-old children, not representative of all age groups.

The Modern Standard: DIAAS

The DIAAS method was developed to overcome these deficiencies, providing a more accurate measure of protein quality based on true ileal digestibility. Instead of measuring digestibility in the feces, DIAAS measures the amino acids absorbed at the end of the small intestine (the ileum), which gives a much more precise figure for what the body can actually utilize.

  • Individual Amino Acid Digestibility: DIAAS calculates the digestibility of each indispensable amino acid individually, offering a more nuanced picture of a protein's true quality.
  • Untruncated Score: DIAAS scores are not capped at 1.0 and can exceed 100%. This allows for a more accurate ranking of all protein sources and reveals the greater nutritional value of higher-quality proteins, like whey, compared to others.
  • Age-Specific Requirements: The reference pattern used for DIAAS is tailored to different age groups, providing more relevant data for a wider population, including infants, children, and adults.

Why the Shift to DIAAS Matters for Consumers

For most consumers, the change from PDCAAS to DIAAS is about receiving a more honest and reliable assessment of the nutritional value of their food. The improved accuracy means that:

  • Informed Decisions: Shoppers can make better-informed choices about protein sources, especially when comparing animal-based and plant-based options.
  • Identifying Quality: DIAAS provides a clear way to distinguish between different high-quality proteins. For example, a whey protein isolate with a DIAAS of 109% is clearly a higher quality source than a soy protein isolate with a DIAAS of 90%.
  • Food Formulation: Food manufacturers can use DIAAS to formulate products with optimal protein content and quality, especially for specific needs like infant formula.

PDCAAS vs. DIAAS: A Comparative Table

Feature PDCAAS (Protein Digestibility Corrected Amino Acid Score) DIAAS (Digestible Indispensable Amino Acid Score)
Calculation Basis Compares amino acid profile to a reference and corrects for total fecal protein digestibility. Compares individual indispensable amino acid content to a reference, corrected for ileal amino acid digestibility.
Digestibility Measurement Uses overall, crude fecal protein digestibility. Measures true digestibility of individual amino acids at the end of the small intestine (ileum).
Accuracy Prone to overestimating protein quality, especially for plant-based proteins. More accurate and reliable measure of protein quality.
Scoring Range Truncated at a maximum score of 1.0, failing to distinguish between top-tier proteins. Untruncated, allowing scores to exceed 100% for superior protein sources.
Animal Model Typically tested using rats, which do not perfectly mimic human digestion. Typically tested using pigs, whose digestive system is more similar to humans.
Reference Pattern Based on the amino acid needs of 2- to 5-year-old children. Offers three specific reference patterns for different age groups: infants, young children, and older children/adults.
FAO Recommendation Previously recommended method (1991). Recommended replacement for PDCAAS (2013).

Limitations and Ongoing Evolution

While DIAAS is a significant improvement, it's not without its own challenges. The ileal digestibility testing is more complex and costly than fecal measurements, meaning not all food items have a publicly available DIAAS score yet. Additionally, critics argue that until a comprehensive database of DIAAS scores is widely available and integrated into food labeling, PDCAAS remains a more accessible tool for consumers. The long-term impact on regulatory frameworks and nutritional guidelines is still being evaluated.

Ultimately, understanding the shift from PDCAAS to DIAAS is key to appreciating the advancements in nutritional science. It provides a more precise and accurate framework for evaluating protein quality, guiding both consumers and food producers toward better nutritional outcomes. While PDCAAS was a useful tool for its time, DIAAS offers a more complete picture of how the body uses protein, allowing for more informed dietary choices.

The Future of Protein Evaluation

The move toward DIAAS reflects a broader trend in nutritional science to rely on more granular and accurate data. The Food and Agriculture Organization of the United Nations (FAO) has championed this shift to better assess the nutritional value of proteins, aiding in global health initiatives and dietary recommendations. As data collection for DIAAS becomes more widespread and efficient, it will likely become the universal standard, making a once-niche concept a staple of modern nutritional labeling. The key is to remember that these scores are tools to help inform choices, not the sole determinant of a healthy diet, which should always be balanced and varied. For more detail on the FAO's stance, you can read their official report on protein quality evaluation.

Frequently Asked Questions

The DIAAS (Digestible Indispensable Amino Acid Score) is widely considered more accurate than PDCAAS because it accounts for true ileal amino acid digestibility and provides an untruncated score.

Ileal digestibility measures the amino acids absorbed in the small intestine before they are altered by bacteria in the large intestine. Fecal digestibility measures waste products, which can overestimate how much protein was actually absorbed by the body.

Yes, unlike PDCAAS, which is truncated at a maximum score of 1.0 (or 100%), DIAAS scores can exceed 100% for very high-quality proteins. This allows for a more detailed comparison between superior protein sources.

A higher, untruncated DIAAS score more accurately distinguishes the superior nutritional quality of proteins like whey compared to others that might have a similar (or 1.0) PDCAAS score, giving consumers better information.

The Food and Agriculture Organization (FAO) of the United Nations recommended replacing PDCAAS with DIAAS in 2013, citing its superior accuracy.

The DIAAS system can provide a more accurate reflection of plant-based protein quality by accounting for individual amino acid digestibility, which is often lower than animal proteins. This helps clarify their true nutritional value.

While recommended by the FAO, DIAAS is not yet universally adopted for food labeling. For now, PDCAAS remains the most common standard used in many regions, but the transition towards DIAAS is expected to continue.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.