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What is the most absorbable form of calcium?

4 min read

The National Institutes of Health recommends taking calcium in doses of 500 mg or less at once for optimal absorption. However, the type of calcium supplement plays a crucial role in how effectively the body uses it. This is essential for health benefits and avoiding deficiencies.

Quick Summary

Calcium citrate is the most easily absorbed form of calcium, especially for individuals with low stomach acid or taking acid-reducing drugs. Calcium citrate malate offers even higher bioavailability and is gentle on the stomach. Calcium carbonate needs food for optimal absorption.

Key Points

  • Calcium Citrate Malate (CCM): Often recognized as one of the most absorbable forms of calcium because of its high solubility.

  • Calcium Citrate: Is more easily absorbed than calcium carbonate, especially on an empty stomach or for those with low stomach acid.

  • Calcium Carbonate: Requires stomach acid for absorption and should be taken with meals; it contains a higher percentage of elemental calcium per pill.

  • Dosing is Key: Calcium supplements should be taken in smaller doses of 500 mg or less at a time throughout the day for optimal absorption.

  • Vitamin D is Essential: Adequate vitamin D levels are crucial, as vitamin D helps the body absorb calcium more effectively from the gut.

  • Digestive Sensitivity: Calcium citrate and CCM are gentler on the stomach and less likely to cause constipation compared to calcium carbonate.

  • Individual Needs Vary: The best form depends on factors like stomach acid levels, dietary habits, and sensitivity to digestive side effects.

In This Article

What is Elemental Calcium?

Elemental calcium is the actual amount of calcium the body absorbs and uses for bone health, muscle function, and nerve transmission. Different calcium compounds contain varying percentages of elemental calcium. For example, calcium carbonate contains about 40% elemental calcium, while calcium citrate has only about 21%. While calcium carbonate offers more calcium per pill, its absorption efficiency is lower than that of calcium citrate in certain conditions.

Calcium Citrate vs. Calcium Carbonate: The Primary Comparison

The two most common forms of calcium supplements are calcium citrate and calcium carbonate. The key differences in their chemical composition and how they are processed by the body significantly impact their absorption and suitability for different individuals.

Calcium Citrate: The Highly Absorbable Option

Calcium citrate is a highly soluble form of calcium that does not require an acidic environment to be absorbed. This makes it an excellent choice for individuals with low stomach acid, which often occurs in older adults and those taking acid-blocking medications. Its superior absorption means more of the mineral reaches the bloodstream, even when taken on an empty stomach. Furthermore, it is less likely to cause gastrointestinal side effects such as constipation, bloating, and gas, which are common complaints with calcium carbonate. A 2001 meta-analysis published in PubMed found that calcium citrate was absorbed approximately 22% to 27% better than calcium carbonate.

Calcium Carbonate: The Affordable and Common Choice

Calcium carbonate is the most widely available and cost-effective calcium supplement, found in products like Tums and Caltrate. It contains a higher percentage of elemental calcium than calcium citrate, meaning fewer tablets may be needed to reach the target dose. However, its absorption is highly dependent on stomach acid, so it must be taken with food to ensure adequate dissolution and uptake. For those with normal stomach acid, calcium carbonate can be a perfectly effective option, provided it is taken correctly. It may, however, cause mild constipation or bloating in some individuals.

Comparison Table: Calcium Forms

Feature Calcium Citrate Calcium Carbonate Calcium Citrate Malate
Absorption Highly absorbable, even on an empty stomach Requires food for optimal absorption; needs stomach acid Excellent, high bioavailability; very soluble
Elemental Calcium Approx. 21% by weight Approx. 40% by weight Approx. 20-24% by weight
Cost Generally more expensive Lower cost, more widely available Varies, often higher cost due to superior form
Side Effects Less likely to cause gas, bloating, or constipation May cause constipation, gas, and bloating in some people Gentle on the stomach; less likely to cause digestive issues
Ideal for Older adults, individuals on acid blockers, those with low stomach acid People with normal stomach acid who take supplements with meals Those seeking the highest bioavailability, individuals with sensitive stomachs

The Rising Star: Calcium Citrate Malate

For those seeking the pinnacle of calcium absorption, calcium citrate malate (CCM) often takes the top spot. It combines calcium, citric acid, and malic acid, a compound naturally found in fruits like apples. This combination results in a highly soluble and bioavailable form of calcium, superior even to standard calcium citrate, especially when vitamin D levels are low. CCM can be taken at any time, with or without food, making it extremely convenient. It is also gentle on the stomach and does not increase the risk of kidney stones, which can be a concern with other forms. Many fortified foods, particularly certain fruit juices, are made with CCM due to its excellent solubility and high absorption rate.

Other Forms of Calcium

While citrate and carbonate are the most common, other forms exist with varying levels of elemental calcium and absorption characteristics. These include:

  • Calcium Gluconate and Lactate: Contain less elemental calcium (9% and 13%, respectively) and are generally less practical for supplementation due to the larger number of tablets required.
  • Calcium Phosphate: Provides a good percentage of elemental calcium (up to 38%) but is limited by low solubility and absorption compared to calcium carbonate.
  • Coral Calcium: Derived from fossils, this type can offer calcium along with other trace minerals but needs careful sourcing to ensure purity and avoid potential heavy metal contamination.
  • Microcrystalline Hydroxyapatite (MCHA): A bone-derived supplement that contains calcium and other bone-supporting minerals. Some research suggests it might be beneficial for bone density, though further study is needed.

Factors that Influence Calcium Absorption

Choosing the right form is just one piece of the puzzle. Several other factors influence how effectively the body absorbs and utilizes calcium.

  • Vitamin D Status: Vitamin D is crucial for calcium absorption. It acts as a hormone, signaling the gut to absorb calcium. A deficiency in vitamin D can significantly impair calcium uptake, regardless of the form consumed.
  • Dosage and Timing: The body can only absorb a limited amount of calcium at a time. Taking more than 500 mg of elemental calcium in a single dose can decrease absorption efficiency. It is best to split larger doses throughout the day.
  • Dietary Intake: Other dietary components can interfere with absorption. For instance, phytates found in whole grains and legumes can bind to calcium, as can oxalates in certain green vegetables like spinach. High sodium intake can also increase calcium excretion.
  • Age and Health Conditions: Calcium absorption naturally declines with age. Additionally, conditions like inflammatory bowel disease (IBD) or celiac disease can hinder nutrient absorption in the gut.

Conclusion

Calcium citrate and calcium citrate malate are notable for their superior absorption, especially for those with low stomach acid or sensitive digestion. Calcium citrate is a reliable choice for effective, gentle supplementation, while calcium citrate malate may offer even higher bioavailability. Calcium carbonate remains a cost-effective option for those who can tolerate it well and remember to take it with food. Optimal absorption depends on proper dosing (ideally 500 mg or less at a time), timing, and adequate vitamin D intake. It's recommended to consult a healthcare provider to determine the best form and dosage for individual needs.

Choosing a calcium supplement - Harvard Health

Frequently Asked Questions

Calcium citrate is often recommended for older adults because stomach acid production naturally decreases with age, and this form absorbs effectively without needing a highly acidic environment.

For most healthy people, obtaining sufficient calcium from a balanced diet is possible through dairy products, leafy greens like kale and bok choy, and fortified foods. Supplements are typically for filling gaps where dietary intake is insufficient.

While excessive calcium intake from supplements can increase the risk of kidney stones in some individuals, research suggests that calcium citrate malate may not worsen the problem. Getting calcium from food is considered safer regarding cardiovascular and kidney risks.

For optimal absorption of calcium carbonate, you should always take it with food. The stomach acid produced during a meal helps break down the supplement for better uptake.

You should check the label for the amount of elemental calcium, the serving size, and whether it contains vitamin D for enhanced absorption. Look for seals of quality from organizations like USP.

Yes, calcium supplements can interfere with the absorption of certain medications, including antibiotics and some blood pressure medications. It's important to consult a healthcare provider or pharmacist about potential interactions.

Studies suggest that calcium citrate malate may offer better absorption compared to standard calcium citrate, especially in individuals with low vitamin D. Its high solubility and bioavailability make it an excellent choice for maximum uptake.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.