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What protein source has the highest biological value?

4 min read

While whole eggs have long been considered the benchmark for protein quality with a Biological Value (BV) of 100, modern processed whey protein isolate can actually achieve an even higher relative score. This measurement determines how efficiently the body uses the protein consumed for growth and maintenance.

Quick Summary

The biological value (BV) measures a protein's efficiency for body use. The highest BV sources are whey protein isolate and eggs, which provide a complete amino acid profile.

Key Points

  • Eggs are the Traditional Benchmark: Whole chicken eggs have historically been considered the gold standard for protein quality, with a Biological Value (BV) of 100.

  • Whey Protein Surpasses Eggs in BV: Processed whey protein isolate can achieve a higher relative BV score (over 100) due to its rapid absorption and specific amino acid profile.

  • BV Measures Efficiency, not Quantity: Biological Value quantifies how efficiently the body utilizes the absorbed protein for bodily functions like growth and repair.

  • Combining Plant Proteins Boosts BV: Plant-based protein sources can be combined strategically to compensate for missing amino acids, thereby creating a more complete and high-BV protein.

  • Whole Eggs Offer More Than Just Protein: The entire egg, including the yolk, provides additional micronutrients and factors that offer benefits beyond the protein alone, such as increased muscle synthesis.

  • Diverse Protein Intake is Optimal: For overall health, incorporating a variety of high-quality protein sources, both animal and plant-based, is the most effective approach.

In This Article

What Is Biological Value?

Biological Value (BV) is a metric used to measure the efficiency of protein utilization by the human body. It is a ratio that quantifies the amount of protein absorbed from food that is retained and used by the body for growth and repair. A protein with a higher BV is considered more 'complete' because it contains all nine essential amino acids in the right proportions needed for bodily functions. The concept assumes that protein is the sole nitrogen source and is calculated based on nitrogen intake versus nitrogen excretion. While raw figures might be presented, the standard scale often uses whole egg protein as the reference point, giving it a score of 100.

The Top Contenders: Eggs vs. Whey Protein

For decades, the humble chicken egg was the gold standard for protein quality, a perfect example of a complete protein with a BV of 100. It was the benchmark against which all other protein sources were measured, praised for its ideal amino acid composition. However, advances in food science have introduced supplements that can surpass this benchmark, notably whey protein isolate.

Why Whey Can Score Higher

Whey protein, a byproduct of cheese production, contains a fast-digesting profile of amino acids, especially the branched-chain amino acids (BCAAs) important for muscle synthesis. The processing that creates whey protein isolate results in a product with a superior relative BV, sometimes reported as high as 154, because it is more readily absorbed and utilized by the body. This rapid absorption makes it a favorite for post-workout recovery. While eggs offer a more sustained release of amino acids, whey is engineered for quick utilization.

The Case for Whole Eggs

Despite whey's higher potential BV score, whole eggs offer unique nutritional benefits. The yolk contains valuable micronutrients, healthy fats, and other factors that can enhance muscle protein synthesis. While egg whites are a great source of pure protein, consuming the whole egg provides a broader spectrum of nutrients that contribute to overall health. Whole eggs represent a complete, natural food source, while whey is a processed supplement. The choice between the two often comes down to specific dietary goals and timing. For instance, consuming whole eggs has been shown to stimulate greater myofibrillar protein synthesis than egg whites alone.

High Biological Value Protein Comparison

Several other foods are considered high-BV protein sources. Animal-based proteins, in general, provide a more complete amino acid profile than most plant-based options. The following table ranks some common sources by their approximate Biological Value, using the standard 100-point scale based on eggs.

Protein Source Approximate Biological Value (BV)
Whey Protein Isolate 104+
Whole Egg 100
Cow's Milk 91
Human Milk 95
Fish 83
Beef 80
Soybeans 74
Casein 77
Quinoa 83
Rice 56

The Importance of Protein Complementarity

For those relying on plant-based diets, achieving high biological value is still possible through a strategy called protein complementarity. This involves combining different protein sources, each with a different limiting amino acid, within the same meal or throughout the day. By pairing foods, you can create a complete protein profile that rivals animal sources.

Examples of complementary protein pairings:

  • Rice and beans: Rice is low in the amino acid lysine, while beans are low in methionine. Combined, they form a complete protein source.
  • Peanut butter on whole-grain bread: The grains provide methionine, while the legumes (peanuts) supply lysine.
  • Hummus and pita bread: The chickpeas in hummus complement the wheat in the pita bread.
  • Lentils and rice: A classic combination in many cultures that provides a balanced amino acid profile.
  • Potatoes and eggs: Some combinations can achieve exceptionally high BVs, such as potatoes and eggs, with one study finding a BV of 136 for this combination.

Beyond Biological Value: Other Metrics for Protein Quality

While BV is a useful tool, it has limitations. It doesn't account for how well the protein is digested and absorbed, only how much of the absorbed protein is retained. Other, more modern metrics have emerged to address these shortcomings, such as the Protein Digestibility Corrected Amino Acid Score (PDCAAS) and the Digestible Indispensable Amino Acid Score (DIAAS).

  • PDCAAS: Corrects the amino acid score for digestibility, setting a benchmark of 1.0. High-quality proteins like whey, casein, and egg all score 1.0, though this can make distinguishing the absolute best sources difficult.
  • DIAAS: Considered a more accurate and advanced metric, it addresses limitations of PDCAAS by focusing on the digestibility of individual amino acids in the small intestine. Whey protein isolate often scores higher on the DIAAS scale compared to other sources.

Ultimately, understanding these different measures provides a more comprehensive view of protein quality. For most people with a varied diet, a combination of high-BV and complementary protein sources will ensure adequate intake of all essential amino acids. High-quality protein from natural food sources like eggs and milk remain an excellent choice for general health and muscle support, while supplements like whey protein offer a convenient and highly bioavailable option for athletes or individuals with specific needs.

Conclusion

While the chicken egg is historically celebrated as the protein source with the highest biological value, modern science shows that processed whey protein isolate can actually surpass it on a relative scale. However, relying solely on a single metric can be misleading. Whole eggs offer a powerful, nutrient-dense package that supports overall health and muscle synthesis. For optimal nutrition, a diverse intake of high-quality proteins from sources like eggs, dairy, and lean meats—or strategically combined plant proteins—is most effective. Both eggs and whey protein offer distinct advantages depending on an individual's dietary goals, but the concept of BV solidifies their status at the pinnacle of protein quality.

For more in-depth information on the health benefits of egg protein, including its role in muscle synthesis and combating malnutrition, you can read more in the National Institutes of Health article on egg protein.

Frequently Asked Questions

Biological value (BV) is a measure of protein quality that indicates how efficiently the body uses the absorbed protein for growth and maintenance. A higher BV means the protein contains a better balance of essential amino acids for the body's needs.

BV is often measured on a scale where egg protein is set as the reference standard of 100. Whey protein isolate is so efficiently absorbed and utilized that its relative BV can exceed this traditional benchmark, sometimes rated as high as 154.

Animal proteins generally have a higher BV because they are 'complete' proteins, containing all essential amino acids in the right proportions. However, combining different plant protein sources throughout the day can create a complete amino acid profile, effectively increasing their overall BV.

Besides eggs and whey, other animal protein sources with high biological values include milk, fish, and lean beef. Their scores typically fall in the 80-95 range, making them highly efficient for the body.

For immediate post-workout recovery, fast-absorbing whey protein is often preferred. However, whole eggs provide a more sustained amino acid release and a broader nutrient profile from the yolk, which also supports muscle synthesis. Both are excellent choices depending on your timing and dietary preferences.

Protein complementarity is the practice of combining two or more plant protein sources with different limiting amino acids within the same meal or day. This ensures that the body receives all essential amino acids, increasing the overall protein quality of the meal.

No, biological value is an older metric with limitations. Newer, more comprehensive methods include the Protein Digestibility Corrected Amino Acid Score (PDCAAS) and the Digestible Indispensable Amino Acid Score (DIAAS). DIAAS is currently considered the most accurate measure.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.