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Where is Citrulline Found? Natural Sources and Health Benefits

4 min read

While the body can synthesize citrulline, the amino acid is most notably found in abundance in watermelon, from which it derives its name, Citrullus. Discover where is citrulline found and how incorporating these foods into your diet can support improved blood flow and exercise performance.

Quick Summary

Citrulline, a non-essential amino acid, is predominantly found in the fruit watermelon but also occurs in other cucurbit family vegetables like cucumbers and squash. Dietary intake supports nitric oxide production, which enhances blood flow and may improve cardiovascular and athletic health.

Key Points

  • Watermelon is King: Watermelon is by far the most abundant natural source of citrulline, and its name, Citrullus, is derived from it.

  • Rind is Rich: The rind of the watermelon often contains higher concentrations of citrulline than the flesh, especially when compared on a dry weight basis.

  • Cucurbit Family Sources: Other foods in the same family as watermelon, including cucumbers, squash, and other melons, also contain citrulline in smaller amounts.

  • Indirect Nitric Oxide Booster: The body converts citrulline into arginine, which is then used to produce nitric oxide, a compound that relaxes blood vessels and improves blood flow.

  • Health and Performance Benefits: Increased dietary citrulline can support cardiovascular health by lowering blood pressure and enhance athletic performance and recovery through improved circulation.

In This Article

The Primary Source: Watermelon

Watermelon is unequivocally the most significant natural food source of L-citrulline. In fact, the amino acid's name is derived from the Latin word for watermelon, Citrullus. Not all watermelons are created equal when it comes to citrulline content, as concentration can vary based on the specific type, ripeness, and even the part of the fruit. Yellow-fleshed varieties, for instance, may contain higher concentrations than red-fleshed ones on a dry weight basis.

Watermelon parts and citrulline levels

  • Flesh: The sweet red or yellow pulp is rich in citrulline, though some studies suggest the rind has even higher concentrations when measured by dry weight.
  • Rind: The often-discarded white part of the watermelon, between the skin and the flesh, is an excellent source of citrulline and often richer than the flesh. Watermelon rind pickle is one way to consume this part of the fruit.
  • Skin: The outermost green peel also contains citrulline, along with other bioactive compounds and antioxidants.

Other Cucurbitaceae Family Members

Since watermelon belongs to the Cucurbitaceae family, other members of this plant family are also known to contain citrulline, though in much lower concentrations. Incorporating a variety of these foods can still contribute to your overall intake.

List of other cucurbit sources

  • Cucumbers: A refreshing, water-filled food that contains some citrulline, though significantly less than watermelon.
  • Squash: Both summer squash (like zucchini) and winter squash (like pumpkin) contain trace amounts of citrulline.
  • Melons: Other melons, such as casaba and cantaloupe, are also sources of the amino acid. Mouse melon (or Mexican sour cucumber) and horned melon are other examples.
  • Bitter Gourd: Also known as bitter melon, this vegetable contains citrulline, with the highest concentration found in the fleshy covering of its seeds.

Other Dietary Sources

Beyond the cucurbit family, certain other foods can provide smaller amounts of citrulline. However, for a meaningful increase in dietary citrulline, focusing on watermelon is the most effective approach.

Foods containing lower amounts of citrulline

  • Nuts: Specific types of nuts, like peanuts and walnuts, have been reported to contain some citrulline.
  • Legumes: Legumes such as chickpeas are also a minor source.
  • Onions and Garlic: These common ingredients can also contribute small amounts.
  • Meat: Some meat products contain citrulline as well.

Comparison of Citrulline Content in Selected Foods

To put the concentration levels into perspective, here is a comparison of citrulline content across different food categories. Note that values can vary based on variety, ripeness, and preparation.

Food Source Relative Citrulline Content Notes
Watermelon Flesh Highest Can vary significantly by variety and ripeness.
Watermelon Rind Highest (by dry weight) Often higher than the flesh on a concentrated basis.
Cucumber Low to Moderate Still contains notable amounts, though far less than watermelon.
Pumpkin Low A modest source of the amino acid.
Nuts Trace Contribution is minor compared to cucurbits.
Legumes (Chickpeas) Trace Can add to overall intake but not a primary source.

How Dietary Citrulline Benefits Your Body

Citrulline's primary function in the body is its conversion into another amino acid, L-arginine, in the kidneys. This process is crucial because L-arginine is a precursor to nitric oxide (NO), a powerful vasodilator.

Increased nitric oxide production offers several health benefits:

  • Improved Blood Flow: By relaxing and widening blood vessels, nitric oxide promotes better circulation throughout the body.
  • Enhanced Exercise Performance: This improved blood flow delivers more oxygen and nutrients to muscles, which can enhance endurance, increase strength performance, and help with recovery.
  • Cardiovascular Health: Better blood flow and reduced blood pressure are key benefits, particularly for individuals with pre-hypertension.
  • Erectile Function: Enhanced blood flow can help improve symptoms of mild erectile dysfunction.

Enhancing Your Citrulline Intake

Incorporating more citrulline-rich foods into your diet is a straightforward process. Here are a few practical ways:

  • Make Watermelon a Staple: Add watermelon to your salads, smoothies, or enjoy it chilled on its own. Don't forget about the rind—try pickling it or blending it into a smoothie with the flesh.
  • Blend a Melon Medley: Combine watermelon with other melons like cantaloupe and casaba for a refreshing, citrulline-boosting fruit salad.
  • Add More Cucurbits: Include cucumbers in your salads and sandwiches, and enjoy squash and pumpkins in soups and roasted dishes throughout the year.
  • Snack on Nuts: Incorporate peanuts and other nuts into your daily snacking routine for a small but consistent dose of citrulline.

Conclusion: Making Citrulline Part of a Healthy Diet

In summary, while our bodies produce some citrulline, the most significant source is dietary, with watermelon taking the top spot. Other members of the Cucurbitaceae family, including cucumbers, squash, and other melons, also contribute to a lesser extent. By increasing your intake of these foods, you can naturally boost nitric oxide production, which supports improved blood flow, cardiovascular health, and athletic performance. Making informed dietary choices can effectively increase your natural citrulline levels and contribute to overall well-being. For more detailed research on this amino acid, consider resources like a comprehensive review on L-citrulline and its impact on health.

Frequently Asked Questions

The best natural source of citrulline is watermelon. Its flesh and rind contain the highest concentrations among known dietary sources.

Yes, citrulline is found in the flesh, rind, and even the skin of the watermelon. The rind often contains a higher concentration than the flesh.

For those seeking therapeutic doses, supplements may be more consistent, but for general health, food sources like watermelon are effective and also provide other nutrients. High doses should be discussed with a doctor.

Yes, consuming citrulline-rich foods increases the body's conversion of citrulline into L-arginine, which is a key precursor to nitric oxide.

No, while cucumbers contain citrulline, the concentration is substantially lower than in watermelon.

Eating citrulline-rich foods can improve blood flow, support cardiovascular health, and enhance athletic performance and recovery by boosting nitric oxide production.

Other foods containing citrulline include other melons (like casaba and cantaloupe), squash, pumpkin, bitter gourd, and trace amounts can also be found in certain nuts and legumes.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.