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Who Should Not Consume Cacao? Understanding Risks and Precautions

5 min read

According to a 2024 review, high-cacao products can contain heavy metals like lead and cadmium, which can pose health issues, especially for children. For this reason and others, there are specific groups of people who should not consume cacao or should do so with great caution.

Quick Summary

This article outlines potential contraindications and risks associated with consuming cacao, including drug interactions, caffeine sensitivity, and gastrointestinal concerns. It details why certain individuals, such as those with heart conditions, anxiety disorders, or specific medical conditions, should avoid or limit their intake.

Key Points

  • Heart and Cardiovascular Issues: Individuals with serious heart conditions or high blood pressure should exercise caution due to cacao's stimulating and vasodilating properties.

  • Medication Interactions: People on antidepressants (MAOIs, SSRIs), blood thinners, and certain stimulants should avoid cacao due to potentially dangerous interactions.

  • Gastrointestinal Sensitivity: Cacao can worsen symptoms for those with GERD, IBS, and other digestive issues by relaxing the lower esophageal sphincter.

  • Pregnancy and Breastfeeding: High consumption is unsafe due to caffeine and heavy metal content, which can affect the fetus and infant. Moderation is key, with medical consultation advised.

  • Caffeine Sensitivity: Those sensitive to stimulants like caffeine may experience nervousness, anxiety, or sleep disturbances from cacao's milder but still present stimulating compounds.

  • Heavy Metal Exposure: Cacao products, especially dark chocolate, can contain heavy metals like lead and cadmium, posing risks to children and pregnant women.

  • Migraine Triggers: Some people who are prone to migraines find that cacao can be a trigger, possibly due to tyramine or histamine sensitivity.

In This Article

Cacao, often celebrated as a superfood, contains powerful compounds that offer numerous health benefits, from antioxidants to mood-enhancing neurotransmitters. However, its potent effects also mean it is not suitable for everyone. Certain medical conditions, medication use, and individual sensitivities can make cacao consumption risky. Understanding these potential contraindications is crucial for safely enjoying its benefits.

Medical Conditions and Cacao Consumption

For individuals with pre-existing medical conditions, the compounds in cacao can interact with or exacerbate symptoms. Consulting a healthcare professional before incorporating cacao into your diet is always recommended, especially if you have a history of chronic illness.

Heart Conditions

Cacao contains theobromine and caffeine, which are stimulants that affect the cardiovascular system. While theobromine generally offers a gentler effect than caffeine, it can still be problematic for people with serious heart problems or irregular heartbeats. The vasodilating effect of cacao can also quickly drop blood pressure, which may cause complications for those with very high blood pressure.

Gastrointestinal Issues

If you suffer from digestive problems, cacao can worsen your symptoms. For example, cacao can relax the lower esophageal sphincter (LES), the muscle that prevents stomach acid from flowing back into the esophagus, which is a known trigger for gastroesophageal reflux disease (GERD). The caffeine in cacao can also worsen diarrhea and other symptoms associated with Irritable Bowel Syndrome (IBS), especially in large quantities.

Anxiety Disorders

Since cacao contains stimulants like caffeine and theobromine, large amounts can potentially worsen anxiety disorders. While some find cacao's mood-boosting compounds like serotonin to be beneficial, those with a sensitivity to stimulants may experience increased nervousness, restlessness, or agitation.

Bleeding Disorders

Cacao can slow blood clotting, and consuming a lot of it might increase the risk of bleeding and bruising in individuals with bleeding disorders. This effect should be a key consideration for anyone with such conditions or who is on medication that affects blood clotting.

Diabetes

Some evidence suggests that cacao can raise blood sugar levels and interfere with blood sugar control, which is a concern for people with diabetes. Monitoring blood sugar levels closely is essential if you have diabetes and choose to consume cacao.

Kidney Disease and Gout

Cacao is noted for containing purine compounds. For individuals with kidney disease and gout, consuming cacao is not recommended as these compounds can lead to the accumulation of uric acid in the body, which can further aggravate their condition.

Migraine Sufferers

For some individuals prone to migraines, chocolate and pure cacao can be a trigger. Although the evidence is mixed and some research suggests cacao may have protective effects, those who know chocolate is a personal trigger should be cautious. Histamine and tyramine sensitivity can play a significant role here.

Medication and Supplement Interactions

Interactions between cacao and certain medications can be severe, potentially altering the drug's effectiveness or causing adverse reactions. Always consult your doctor or pharmacist if you are on medication before consuming cacao.

Antidepressants (MAOIs & SSRIs)

Individuals taking monoamine oxidase inhibitors (MAOIs) should avoid cacao, as the tyramine in cacao can cause a sudden, dangerous spike in blood pressure known as a hypertensive crisis. For those on selective serotonin reuptake inhibitors (SSRIs), the serotonin-enhancing effects of cacao, combined with the medication, may increase the risk of serotonin syndrome, a potentially life-threatening condition.

Blood Thinners

As cacao can slow blood clotting, combining it with anticoagulant or antiplatelet drugs (like warfarin or aspirin) may increase the risk of bruising and bleeding. Close monitoring and medical consultation are necessary.

Stimulant Drugs

Combining cacao with other stimulants, such as ephedrine, ADHD medication, or certain asthma medications, can cause over-stimulation of the heart and nervous system, leading to dangerous heart problems and high blood pressure.

Diabetes Medications

Cacao's potential to affect blood sugar means it can interfere with diabetes medications. Metformin, for instance, has a documented interaction with the caffeine in cacao.

Other Interactions

Cacao's caffeine content can interact with numerous other medications, including birth control pills, certain antibiotics (quinolones), and asthma medications like theophylline. The stimulant can also increase eye pressure, making it risky for those with glaucoma. Before a cardiac stress test, consuming cacao should be stopped at least 24 hours prior, as it can block the effects of test medications like adenosine and dipyridamole.

Comparing Cacao to Other Products

Cacao vs. Coffee vs. Processed Chocolate

Feature Cacao (Pure) Coffee (Brewed) Milk Chocolate (Processed)
Caffeine Content Low to moderate (12-35 mg/serving) High (80-135 mg/serving) Very low (5-25 mg/serving)
Theobromine Content High Trace amounts Present, but less than cacao
Stimulant Effects Gentle, sustained energy boost Quick, intense, and often jittery Minimal
Antioxidants Very high (Flavanols) Present, but varies Lower due to processing
Sugar/Additives Minimal (when raw) None (when black) High
Heavy Metals Potential risk, depending on source Minimal Potential risk
Digestive Impact Can worsen GERD/IBS Can exacerbate digestive issues Can worsen GERD/IBS

Specific Populations: Pregnancy, Breastfeeding, and Children

Pregnancy

While moderate amounts are often considered possibly safe, high consumption of cacao during pregnancy is potentially unsafe. The caffeine crosses the placenta, and high doses are linked to low birth weight, premature delivery, and miscarriage. Additionally, excessive polyphenols in the third trimester have been shown to affect fetal circulation in some studies. The potential presence of heavy metals like lead and cadmium is another serious concern.

Breastfeeding

Large amounts of cacao are possibly unsafe during breastfeeding due to the caffeine content, which passes into breast milk. This can cause irritability and frequent bowel movements in the infant. Therefore, limiting intake is advisable.

Children

Children, especially young children, are more susceptible to potential issues from heavy metals like lead and cadmium that may be present in cacao, particularly in high-cacao products. Given the developmental risks, limiting children's intake is a prudent measure.

Precautions for Safer Consumption

  1. Consult a Professional: If you have any health concerns, are pregnant, breastfeeding, or on medication, speak with a doctor before consuming cacao.
  2. Start with Small Doses: If you are new to cacao, begin with a small amount (around 10-20g) to assess your sensitivity.
  3. Choose High-Quality Products: Opt for brands that test for heavy metals like lead and cadmium to minimize risk.
  4. Avoid Evening Consumption: The stimulant effects of theobromine can disrupt sleep patterns, so it's best to consume cacao earlier in the day.
  5. Monitor Your Body's Response: Pay close attention to any adverse reactions like headaches, digestive upset, or increased anxiety and adjust your intake accordingly.

Conclusion

Cacao offers a wealth of potential health benefits, but its potent compounds mean it's not a universal health panacea. Individuals with heart conditions, gastrointestinal disorders, and anxiety issues, as well as those on certain medications, should approach cacao with caution. Pregnant and breastfeeding individuals and young children also face particular risks. By understanding who should not consume cacao and taking sensible precautions, you can make an informed decision about whether it is a safe addition to your diet. The key lies in moderation, awareness of your body's specific needs, and professional medical advice when in doubt. For additional information on medication interactions, WebMD offers a comprehensive guide.

Frequently Asked Questions

If you are on monoamine oxidase inhibitors (MAOIs) or selective serotonin reuptake inhibitors (SSRIs), you should avoid consuming cacao. The amino acid tyramine in cacao can cause dangerous blood pressure spikes with MAOIs, while its serotonin-enhancing effects can risk serotonin syndrome with SSRIs.

Yes, large amounts of cacao can potentially worsen anxiety disorders due to its stimulant content, including caffeine and theobromine. The effect is highly individual, so those with anxiety or stimulant sensitivity should start with small doses or avoid it entirely.

Cacao should be consumed in moderation, and with caution, during pregnancy and breastfeeding. The caffeine and potential heavy metal content can pose risks to the fetus or infant. High doses are possibly unsafe, and a lower intake is generally recommended.

Cacao can cause or worsen symptoms of GERD and acid reflux because its compounds, including methylxanthine, can relax the lower esophageal sphincter. This allows stomach acid to flow back into the esophagus, leading to heartburn.

Yes, cacao can slow blood clotting. If you are taking anticoagulant or antiplatelet drugs (blood thinners), combining them with cacao could increase the risk of bruising and bleeding. It is vital to consult your doctor.

Some cacao products, particularly dark chocolate, can contain heavy metals like lead and cadmium. This is a significant concern, especially for pregnant women and young children, due to potential developmental and nervous system issues.

Yes, while research is mixed, anecdotal evidence suggests that cacao can trigger migraines in some sensitive individuals. This may be related to compounds like tyramine, histamine, or caffeine. Migraine sufferers should monitor their personal response carefully.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.