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Why do I feel bad when I take magnesium?

4 min read

According to the National Institutes of Health, over half of Americans consume less than the recommended amount of magnesium through their diet. However, some individuals report they feel bad when I take magnesium, experiencing unpleasant side effects that can make supplementation a challenge.

Quick Summary

The discomfort from magnesium can result from excessive dosage, the specific form used, underlying health conditions, or taking it on an empty stomach. Understanding these factors and making simple adjustments, like switching forms or lowering the dose, can often resolve the issue.

Key Points

  • Dosage Matters: Taking more than 350 mg of supplemental magnesium at once significantly increases the risk of diarrhea, nausea, and cramping.

  • Form Influences Side Effects: Poorly absorbed forms like magnesium oxide are more likely to cause digestive upset, whereas chelated forms like glycinate are gentler on the stomach.

  • Empty Stomach Irritation: Taking magnesium on an empty stomach can trigger nausea and other gastrointestinal issues. Taking it with food can minimize this risk.

  • Underlying Conditions are a Factor: Kidney disease or other GI issues can affect how your body processes magnesium, increasing the potential for negative side effects.

  • Check for Medication Interactions: Magnesium can interfere with the absorption of antibiotics and other drugs, making professional medical advice necessary.

  • Lifestyle Adjustments Help: Optimizing your diet with magnesium-rich foods and splitting your dose can resolve many issues without stopping supplementation entirely.

In This Article

The Root Causes: Why Magnesium Can Make You Feel Bad

Magnesium is a vital mineral involved in more than 300 biochemical reactions in the human body, playing a crucial role in nerve and muscle function, blood pressure regulation, and energy production. Despite its importance, some people experience negative reactions when taking supplements. The reasons for this discomfort can be complex, ranging from the type of magnesium used to a person’s individual physiology. Recognizing the root cause is the first step toward finding a solution that works for you.

High Dosage and Magnesium Toxicity

One of the most common reasons for feeling unwell is simply taking too much magnesium. While your kidneys can efficiently excrete excess magnesium from food, high doses from supplements can overwhelm your system. Side effects typically start with gastrointestinal distress, such as nausea, diarrhea, and abdominal cramping. The Tolerable Upper Intake Level (UL) for supplemental magnesium is 350 mg for adults. Consuming doses higher than this, especially with certain laxative forms, significantly increases the risk of side effects. In very rare and extreme cases, very high doses can lead to hypermagnesemia, or magnesium toxicity, which causes more severe symptoms like lethargy, low blood pressure, muscle weakness, and an irregular heartbeat.

Different Forms and Bioavailability

Not all magnesium supplements are created equal. The compound that elemental magnesium is bound to dramatically affects its bioavailability (how well your body absorbs it) and its impact on your digestive system. Poorly absorbed forms can remain in your intestine, pulling water into the bowel and causing a laxative effect. Magnesium oxide, for instance, has low bioavailability and is more likely to cause gastrointestinal issues. In contrast, well-absorbed chelated forms, like magnesium glycinate, are gentler on the stomach.

Taking Magnesium on an Empty Stomach

Taking any supplement without food can irritate a sensitive stomach, and magnesium is no exception. For some individuals, the concentrated dose of minerals on an empty stomach can lead to nausea and stomach pain. Taking your supplement with a meal can help buffer this effect and reduce the chance of digestive upset.

Underlying Health Conditions

Certain pre-existing health issues can increase your sensitivity to magnesium or impair your body’s ability to process it correctly. Individuals with kidney problems, for example, are at a higher risk of hypermagnesemia because their kidneys cannot efficiently filter out excess magnesium. Gastrointestinal disorders like Crohn’s disease or celiac disease can also affect how magnesium is absorbed and tolerated. If you have a known health condition, it is crucial to consult your doctor before starting any supplementation.

Medication Interactions

Magnesium can interact with various medications, altering their effectiveness or causing adverse effects. It can decrease the absorption of certain antibiotics, and its blood pressure-lowering effect can be amplified when taken with calcium channel blockers. Always discuss all your medications with a healthcare provider before adding a magnesium supplement to your routine.

How to Prevent or Manage Side Effects

If you find that magnesium makes you feel bad, there are several steps you can take to mitigate the issue:

  • Reduce your dose: Many people can tolerate a lower, more frequent dose better than a single high dose.
  • Take with food: This is one of the simplest and most effective ways to reduce stomach discomfort.
  • Switch supplement forms: Choose a more bioavailable, gentler form like glycinate over forms known to have a strong laxative effect, such as oxide.
  • Space out your dosage: Consider taking smaller doses throughout the day instead of one large one.

Comparison of Common Magnesium Supplement Forms

Magnesium Form Bioavailability Common Uses Likelihood of Side Effects
Magnesium Oxide Low Constipation, antacid High (laxative effect)
Magnesium Citrate High Constipation, supplements Moderate (can cause diarrhea)
Magnesium Glycinate High Anxiety, sleep, relaxation Low (gentle on stomach)
Magnesium Malate High Muscle function, energy Low (well-tolerated)

Natural Sources of Magnesium

Before turning to supplements, many people can increase their magnesium intake through diet. Magnesium is naturally present in a variety of healthy foods. Incorporating more of these into your meals can help you meet your daily needs without the risk of supplemental side effects. Good food sources include:

  • Leafy Greens: Spinach and kale are excellent sources.
  • Nuts and Seeds: Almonds, pumpkin seeds, and chia seeds are especially rich in magnesium.
  • Whole Grains: Brown rice, oats, and whole wheat are good options.
  • Legumes: Black beans, lentils, and chickpeas are great additions.
  • Dark Chocolate: A delicious way to boost your magnesium intake in moderation.

Conclusion

Experiencing unpleasant side effects like digestive upset after taking magnesium supplements is a common and often fixable problem. While magnesium is an essential mineral for overall health, the form, dosage, and timing of supplementation can significantly influence how your body reacts. Adjusting your regimen by taking a lower dose, switching to a more bioavailable form like glycinate, or taking it with food can often alleviate discomfort. For persistent issues, or if you have a pre-existing medical condition, consulting a healthcare professional is the best course of action to determine the right approach for your needs and ensure safe supplementation. For general nutritional information, authoritative resources like the Office of Dietary Supplements at the National Institutes of Health provide valuable insights.


Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult a healthcare professional before starting any new supplement regimen.

Frequently Asked Questions

Forms with high bioavailability, such as magnesium glycinate, magnesium malate, and magnesium taurate, are less likely to cause digestive issues because they are absorbed more efficiently by the body.

While magnesium deficiency has been linked to migraines and headaches, a sudden spike in intake or an excessive dose could potentially cause headaches in some individuals. Magnesium toxicity is also associated with headaches.

The best time depends on your personal goals and how you react. Some prefer taking it at night for relaxation, while others take it in the morning for consistent levels. Taking it with food is more important than timing for many people.

Diarrhea is a common side effect of magnesium supplements, especially with poorly absorbed forms like oxide or high doses of citrate. Unabsorbed magnesium draws water into the intestines, acting as a laxative.

The Tolerable Upper Intake Level (UL) for supplemental magnesium in adults is 350 mg per day. It is recommended not to exceed this without a doctor's supervision.

Magnesium can have a blood pressure-lowering effect. If you are already on blood pressure medication, taking high doses of magnesium could potentially cause your blood pressure to drop too low, especially with certain supplement types. Consult your doctor first.

Signs of a magnesium overdose (hypermagnesemia) can include nausea, diarrhea, low blood pressure, muscle weakness, fatigue, lethargy, and an irregular heartbeat. Seek medical attention if you experience these symptoms.

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.