Defining Your Review's Purpose and Scope
Before you can begin writing, you must clearly define the purpose and scope of your review. Are you providing a broad overview of a topic, or are you conducting a detailed systematic analysis to answer a specific clinical question? The type of review you write will determine your methodology.
Narrative vs. Systematic Reviews
- Narrative Reviews: Provide a broad overview of a topic, often based on the author's expertise. They are useful for introducing a subject but are more susceptible to bias and may not cover all relevant literature comprehensively.
- Systematic Reviews: Use transparent, reproducible methods to identify, select, and critically appraise all relevant research on a focused question. They aim to minimize bias and produce a more robust synthesis of evidence. A meta-analysis, a quantitative form of systematic review, may be used if the studies are sufficiently similar for statistical combination.
Formulating the Research Question
For a systematic review, a well-defined research question is critical. The PICOS framework is a standard tool for structuring this question:
- P (Population/Participants): Who are you studying? (e.g., adults with type 2 diabetes)
- I (Intervention): What is the exposure or intervention? (e.g., consumption of whole grains)
- C (Comparison): What is the comparison group? (e.g., consumption of refined grains)
- O (Outcome): What are the measurable health outcomes? (e.g., changes in blood glucose levels)
- S (Study Design): What types of studies will you include? (e.g., randomized controlled trials)
The Research Phase: Finding and Appraising Evidence
This stage involves a meticulous search for all relevant literature. The goal is to be comprehensive and transparent to ensure the review is as unbiased as possible.
Conducting a Comprehensive Literature Search
- Select Databases: Use multiple reputable scientific databases relevant to nutrition, such as PubMed, Embase, and the Cochrane Library.
- Develop Search Strategy: Create a list of keywords and search terms based on your PICOS question. Use Boolean operators (AND, OR, NOT) to refine your search.
- Identify Sources: Search for primary sources (original research articles) and secondary sources (existing review articles). Also, consider grey literature from government reports or conference abstracts.
- Record Search Process: Document all databases, keywords, and search criteria used. This ensures your review is reproducible and transparent.
Screening and Selecting Studies
Using the inclusion and exclusion criteria you defined, you will screen the studies you identified in the previous step.
- Initial Screening: Review titles and abstracts to remove irrelevant articles.
- Full-Text Review: Obtain the full text of potentially relevant articles and assess them against your criteria for final inclusion.
Critically Appraising Study Quality
Not all studies are created equal. You must assess the methodological quality and risk of bias of each included study. For example, randomized controlled trials are often considered high-quality evidence, while observational studies may be subject to various biases. Tools from the Cochrane Collaboration or the Academy of Nutrition and Dietetics can aid in this process,.
Data Extraction
Extract key information from each study into a structured table. This can include:
- Author(s) and year
- Study design
- Participant characteristics (age, sex, health status)
- Intervention details (type, duration, dosage)
- Outcome measures
- Key findings
The Writing Phase: Synthesizing and Structuring the Article
Once your research is complete, you can begin to organize and write your review. This is where you transform your extracted data into a cohesive narrative, supported by evidence.
Structuring the Review
An effective review follows a logical flow:
- Introduction: Provides context and background, states the problem, and outlines the review's objective.
- Methods: For systematic reviews, this section details your search strategy, screening process, and critical appraisal methods transparently.
- Results/Body: This is the core of the review. It can be structured chronologically, by theme, or by methodology to synthesize findings from the included studies.
- Discussion: Interprets the results, highlights key findings, compares them with existing literature, discusses limitations, and suggests implications for practice or future research.
- Conclusion: Briefly summarizes the main points and overall impact of the review.
Narrative vs. Systematic Review: A Comparison
| Feature | Narrative Review | Systematic Review | 
|---|---|---|
| Research Question | Broad, general topic exploration | Focused, specific question (e.g., PICOS) | 
| Search Strategy | Unsystematic, based on author knowledge | Explicit, reproducible search terms and criteria | 
| Bias | High potential for selection and reporting bias | Attempts to minimize bias through transparent methods | 
| Study Quality | May not involve rigorous critical appraisal | Mandatory critical appraisal of included studies | 
| Reproducibility | Not easily replicable | Highly reproducible, requires detailed reporting | 
| Primary Use | General overviews, introducing a topic | Evidence-based recommendations, informing policy | 
Conclusion
Writing a comprehensive nutrition review is an invaluable exercise in evidence-based practice. By following a structured and transparent process, from defining the research question to critically appraising and synthesizing the evidence, you can produce a high-quality review that contributes meaningfully to the field of nutritional science. Whether it's a narrative summary or a rigorous systematic analysis, a well-written review is a crucial tool for informing clinical practice and advancing public health. For further guidance on the systematic review process, resources like the PRISMA guidelines can be highly beneficial.