Skip to content

Beriberi: What Disease is Caused by Polished Rice in Human Diet?

3 min read

Historically, beriberi was a major health problem in East Asian countries where diets consisted largely of polished white rice, which lacks essential nutrients. This serious nutritional disorder, known as beriberi, is caused by a severe deficiency of vitamin B1, also called thiamine. The refining process strips rice of its nutrient-rich outer layers, leading to this dangerous condition.

Quick Summary

A diet high in polished white rice can cause beriberi, a disease stemming from thiamine (vitamin B1) deficiency. Polishing removes crucial nutrients, impacting the nervous system (dry beriberi) or cardiovascular system (wet beriberi). Early treatment with thiamine supplements can prevent severe and potentially fatal complications. Modern fortification has reduced its prevalence, though risks persist in certain populations.

Key Points

  • Polished Rice Lacks Thiamine: The refining process that produces white rice strips the grain of its bran and germ, which contain the vital nutrient vitamin B1 (thiamine).

  • Beriberi is the Resulting Disease: A diet dependent on this polished rice leads to beriberi, a severe thiamine deficiency affecting the nervous and cardiovascular systems.

  • Symptoms Manifest in Two Forms: Beriberi can appear as 'dry beriberi,' causing nerve damage and muscle weakness, or 'wet beriberi,' leading to cardiovascular issues like fluid retention and heart failure.

  • Prevention is Dietary: The best prevention is consuming a balanced diet rich in thiamine, either from whole grains like brown rice or from fortified foods.

  • Early Treatment is Crucial: With timely treatment using thiamine supplements, symptoms can often be reversed. However, chronic deficiency can lead to permanent damage.

  • Risk Groups Still Exist: Although rare in developed nations due to food fortification, at-risk groups include individuals with alcohol use disorder, bariatric surgery patients, and those in food-insecure regions.

In This Article

Understanding the Link Between Polished Rice and Beriberi

For centuries, polished white rice has been a staple in diets around the world, particularly in Asia. The process of polishing removes the outer husk, bran, and germ to create a smoother, more appealing white grain with a longer shelf life. However, this refining process also strips away most of the rice's vitamins and minerals, including a significant amount of thiamine (vitamin B1). This loss of a vital nutrient is the direct cause of the deficiency disease known as beriberi.

The Discovery and History of Beriberi

In the late 19th century, scientists in the Dutch East Indies (now Indonesia) like Christiaan Eijkman observed that chickens fed a diet of polished rice developed a beriberi-like illness, while those fed unpolished rice remained healthy. This pivotal observation laid the groundwork for the discovery of vitamins. Later, in 1912, Casimir Funk proposed the existence of 'vitamines,' which were specific factors in food essential for health. The isolation of thiamine from rice bran confirmed the link and led to the eventual eradication of large-scale beriberi outbreaks through dietary changes and food fortification.

The Mechanisms of Thiamine Deficiency

Thiamine is a water-soluble vitamin critical for converting food into energy and for maintaining proper nervous and cardiovascular system function. When a diet consists predominantly of thiamine-deficient polished rice, the body's thiamine stores become depleted over time, leading to beriberi. The deficiency affects cellular metabolism, particularly in tissues with high energy demands like the nerves and heart, resulting in the various forms of the disease.

Types of Beriberi and Their Symptoms

Beriberi manifests in two primary forms, depending on which bodily systems are most affected.

  • Dry Beriberi: This form primarily impacts the nervous system. Symptoms include peripheral neuropathy, which is damage to the nerves outside the brain and spinal cord. This can cause:
    • Numbness or tingling in the hands and feet
    • Muscle weakness or loss of muscle function, especially in the lower legs
    • Pain
    • Difficulty walking and lack of coordination
    • Mental confusion or memory loss in severe cases
  • Wet Beriberi: This form is characterized by damage to the cardiovascular system. It is a medical emergency that can lead to heart failure if left untreated. Symptoms include:
    • Shortness of breath, particularly during physical activity or when lying down
    • Rapid heart rate (tachycardia)
    • Swelling (edema) in the lower legs and feet
    • An enlarged heart

The Role of Rice Processing and Modern Prevention

The difference in nutritional value between polished and unpolished rice is stark. Polished rice removes the bran and germ, losing essential nutrients, while unpolished rice (brown rice) retains these layers, keeping its nutritional profile intact.

Aspect Polished White Rice Unpolished (Brown) Rice
Thiamine (Vitamin B1) Significantly lower due to refining Much higher, retained in the bran and germ
Fiber Content Very low High, promoting digestive health
Glycemic Index (GI) High, causing rapid blood sugar spikes Lower, leading to more gradual blood sugar release
Nutrients Lost Fiber, B vitamins, iron, magnesium All natural nutrients are retained
Shelf Life Longer due to removal of oil-rich germ Shorter, as oils can go rancid if not stored correctly
Cooking Time Faster Longer

In modern times, beriberi is rare in countries with food fortification programs where thiamine is added back into refined grains. However, the disease can still affect at-risk populations, including individuals with alcohol use disorder, those with certain medical conditions affecting nutrient absorption, and people reliant on unenriched grains in undernourished regions.

Treatment and Long-Term Outlook

Treatment for beriberi involves replacing the body's thiamine stores, usually with oral or intravenous thiamine supplements. With prompt and early intervention, many of the symptoms, including heart damage and nervous system impairment, can be reversed. However, if the deficiency is severe and has caused long-term damage, some symptoms may persist. Continued intake of a balanced, thiamine-rich diet is essential for long-term prevention.

Conclusion

For those relying on a diet of polished white rice, the risk of developing beriberi, a dangerous thiamine deficiency, is significant. The refining process, while improving texture and shelf life, removes the crucial vitamin B1 found in the outer layers of the grain. While public health efforts have largely reduced the threat in many parts of the world, awareness of this nutritional link remains critical, especially for vulnerable populations. Choosing whole grains like brown rice or ensuring consumption of fortified foods can prevent this debilitating and potentially fatal disease. For more information on maintaining a balanced diet, consult reliable health resources like the Harvard T.H. Chan School of Public Health Nutrition Source.

Frequently Asked Questions

Polished rice causes beriberi because the milling and polishing processes strip the rice grain of its outer layers (bran and germ), where vitamin B1 (thiamine) is concentrated. A diet based predominantly on this nutrient-deficient rice can lead to a severe lack of thiamine in the body.

Wet beriberi primarily affects the heart and circulatory system, causing symptoms such as rapid heart rate, fluid buildup (edema), and potential heart failure. Dry beriberi, on the other hand, affects the nervous system, leading to nerve damage, muscle weakness, and paralysis in the legs and arms.

Modern enriched white rice has thiamine and other nutrients added back after processing, which significantly reduces the risk of beriberi. However, if someone's diet consists exclusively of unenriched white rice, the risk remains high. A varied diet with other sources of thiamine is always recommended.

Early symptoms of beriberi can be vague and include fatigue, irritability, poor memory, loss of appetite, and weight loss. Progression can lead to more specific neurological or cardiovascular symptoms depending on the type.

To prevent thiamine deficiency, one should eat a balanced diet that includes foods rich in thiamine. Good sources include whole grains (like brown rice), legumes, seeds, nuts, pork, fish, and fortified cereals and breads.

Beriberi is rare in developed countries with food fortification programs. However, it can still affect vulnerable populations, such as individuals with chronic alcohol abuse, bariatric surgery patients, or those in regions with limited food access.

The primary treatment for beriberi is the administration of thiamine supplements, which can be given orally or intravenously depending on the severity of the deficiency. A balanced, nutritious diet is also essential for a full recovery and to prevent recurrence.

References

  1. 1
  2. 2
  3. 3
  4. 4
  5. 5

Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.